{"id":10607,"date":"2022-10-27T02:48:23","date_gmt":"2022-10-26T18:48:23","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=10607"},"modified":"2022-10-27T02:48:23","modified_gmt":"2022-10-26T18:48:23","slug":"mazaher-haji-agha-elnaz-team-published-research-in-physics-and-chemistry-of-liquids-in-2021-2075-46-9","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=10607","title":{"rendered":"Mazaher Haji Agha, Elnaz team published research in Physics and Chemistry of Liquids  in 2021 | 2075-46-9"},"content":{"rendered":"<p>Pyrazoles and pyrimidines have diverse biological and pharmacological activities.  2075-46-9, formula is C3H3N3O2, Name is  4-Nitro-1H-pyrazole.  There are a number of antimicrobial compounds containing pyrazole moiety as the core unit. <a href=\"https:\/\/www.ambeed.com\/products\/2075-46-9.html\">Application In Synthesis of  2075-46-9<\/a>.<\/p>\n<p>Mazaher Haji Agha, Elnaz;Barzegar-Jalali, Mohammad;Mirheydari, Seyyedeh Narjes;Adibkia, Khosro;Martinez, Fleming;Jouyban, Abolghasem research published \u300a Trained models for solubility prediction of drugs in acetonitrile + water mixtures at various temperatures\u300b, the research content is summarized as follows. The trained versions of Jouyban-Acree and modified Wilson models are proposed to predict the drug&#8217;s solubility in {acetonitrile + water} solutions at different temperatures To obtain a full predictive model, the Abraham solvation and Hansen solubility parameters of solutes representing the interaction between components are combined with the proposed models. The solubility data of 12 drugs are fitted by these models. The overall average relative deviation percent (%ARD) values for the back-calculated solubility of drugs in aqueous acetonitrile solutions are 18.3-52.3 for the proposed models. The generally trained models provide acceptable estimation of the solubility of drugs and can be helpful in the pharmaceutical sciences.<\/p>\n<p><a href=\"https:\/\/www.ambeed.com\/products\/2075-46-9.html\">Application In Synthesis of  2075-46-9<\/a>, 4-Nitro-1H-pyrazole, also known as 4-Nitropyrazole, is a useful research compound. Its molecular formula is C3H3N3O2 and its molecular weight is 113.08 g\/mol. The purity is usually 95%.<\/p>\n<p>4-Nitropyrazole, is a building block for the synthesis of various pharmaceutical compounds, including inhibitors, and therapeutic agents. It can be used for the synthesis of highly selective, brain-penetrant aminopyrazole LRRK2 Inhibitor, as a potentially viable treatment for Parkinson&#8217;s disease., 2075-46-9.<\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p><a href=\"https:\/\/www.ambeed.com\/products\/2075-46-9.html\">Application In Synthesis of  2075-46-9<\/a>, 4-Nitro-1H-pyrazole, also known as 4-Nitropyrazole, is a useful research compound. Its molecular formula is C3H3N3O2 and its molecular weight is 113.08 g\/mol. The purity is usually 95%.<\/p>\n<p>4-Nitropyrazole, is a building block for the synthesis of various pharmaceutical compounds, including inhibitors, and therapeutic agents. It can be used for the synthesis of highly selective, brain-penetrant aminopyrazole LRRK2 Inhibitor, as a potentially viable treatment for Parkinson&#8217;s disease., 2075-46-9.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[152,131],"tags":[732],"class_list":["post-10607","post","type-post","status-publish","format-standard","hentry","category-2075-46-9","category-pyrazoles-derivatives","tag-m-w100-150"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Mazaher Haji Agha, Elnaz team published research in Physics and Chemistry of Liquids in 2021 | 2075-46-9 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Pyrazoles and pyrimidines have diverse biological and pharmacological activities. 2075-46-9, formula is C3H3N3O2, Name is 4-Nitro-1H-pyrazole. 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