{"id":10518,"date":"2022-10-21T07:00:22","date_gmt":"2022-10-20T23:00:22","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=10518"},"modified":"2022-10-21T07:00:22","modified_gmt":"2022-10-20T23:00:22","slug":"drikermann-deniss-team-published-research-in-synlett-cas-192701-73-8","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=10518","title":{"rendered":"Drikermann, Denis&#8217;s team published research in Synlett | CAS: 192701-73-8"},"content":{"rendered":"<p>The author of \u300aIntramolecular Cyclization of Vinyldiazoacetates as a Versatile Route to Substituted Pyrazoles\u300b were Drikermann, Denis; Kerndl, Valerie; Goerls, Helmar; Vilotijevic, Ivan. And the article was published in Synlett in . <a href=\"https:\/\/www.ambeed.com\/products\/192701-73-8.html\">Category: pyrazoles-derivatives<\/a> The author mentioned the following in the article:<\/p>\n<p>Vinyldiazo compounds undergo a thermal electrocyclization to form pyrazoles in yields of up to 95%. The reactions are operationally simple, use readily available starting materials, require no intervention of a catalyst, and enable the synthesis of mono-, di- and tri-substituted pyrazoles. With the ability to produce highly substituted pyrazoles and the flexibility in installing various types of substituents, this method constitutes a new entry to this valuable heterocyclic scaffold and may be of interest to all branches of the chem. industry. In addition to this study using Methyl 3-(p-tolyl)-1H-pyrazole-5-carboxylate, there are many other studies that have used Methyl 3-(p-tolyl)-1H-pyrazole-5-carboxylate(cas: 192701-73-8<a href=\"https:\/\/www.ambeed.com\/products\/192701-73-8.html\">Category: pyrazoles-derivatives<\/a>) was used in this study.<\/p>\n<p>Methyl 3-(p-tolyl)-1H-pyrazole-5-carboxylate(cas: 192701-73-8) belongs to pyrazoles. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, monoamine oxidase inhibitory, anti-inflammatory, antipyretic, neuroleptic, anticonvulsant, antiarrhythmic, sedative, muscle relaxant, antidiabetic and antibacterial activities. <a href=\"https:\/\/www.ambeed.com\/products\/192701-73-8.html\">Category: pyrazoles-derivatives<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Methyl 3-(p-tolyl)-1H-pyrazole-5-carboxylate(cas: 192701-73-8) belongs to pyrazoles. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, monoamine oxidase inhibitory, anti-inflammatory, antipyretic, neuroleptic, anticonvulsant, antiarrhythmic, sedative, muscle relaxant, antidiabetic and antibacterial activities. <a href=\"https:\/\/www.ambeed.com\/products\/192701-73-8.html\">Category: pyrazoles-derivatives<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[516,131],"tags":[129],"class_list":["post-10518","post","type-post","status-publish","format-standard","hentry","category-192701-73-8","category-pyrazoles-derivatives","tag-200-300"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Drikermann, Denis&#039;s team published research in Synlett | CAS: 192701-73-8 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"The author of \u300aIntramolecular Cyclization of Vinyldiazoacetates as a Versatile Route to Substituted Pyrazoles\u300b were Drikermann, Denis; Kerndl, Valerie; Goerls, Helmar; Vilotijevic, Ivan. 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