{"id":10411,"date":"2022-10-21T05:01:18","date_gmt":"2022-10-20T21:01:18","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=10411"},"modified":"2022-10-21T05:01:18","modified_gmt":"2022-10-20T21:01:18","slug":"ma-hong-jus-team-published-research-in-pest-management-science-in-2015-cas-20154-03-4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=10411","title":{"rendered":"Ma, Hong-Ju’s team published research in Pest Management Science in 2015 | CAS: 20154-03-4"},"content":{"rendered":"

Recommanded Product: 20154-03-4<\/a>In 2015 ,\u300aDesign, synthesis and herbicidal evaluation of novel 4-(1H-pyrazol-1-yl)pyrimidine derivatives\u300b appeared in Pest Management Science. The author of the article were Ma, Hong-Ju; Zhang, Jian-Hua; Xia, Xiang-Dong; Kang, Jing; Li, Jian-Hong. The article conveys some information:<\/p>\n

A series of novel pyrazolylpyrimidine derivatives I (R1 = H, CH3; R2 = OCH2CH3, SCH3, SO2CH3, N(CH3)2, etc.; R3 = H, CH3; R4 = CF3; X = H, Cl) were designed and synthesized. The herbicidal activities of 30 pyrazolylpyrimidine derivatives were assessed. Nine compounds caused good herbicidal activity for Pennisetum alopecuroides L. Among them, I (R1 = H; R2 = NHCH2CH3; R3 = CH3; R4 = CF3; X = H) exhibited the strongest inhibitory activity against the root growth of P. alopecuroides, with an IC50 of 1.90 mg L-1. Compound I (R1 = CH3; R2 = prop-2-yn-1-yloxy; R3 = CH3; R4 = CF3; X = H) produced the highest inhibition of chlorophyll level in seedlings of P. alopecuroides (IC50 = 3.14 mg L-1). The structure-activity relationship indicated that the alkynyloxy group at the 6-position on the pyrimidine ring played a very important role for bleaching activities. When the alkynyloxy group was replaced by alkoxy, amino, alkylthio and alkylsulfonyl groups, the bleaching activities of the compounds were diminished. However, the compounds substituted by an amino at the 6-position of the pyrimidine ring exhibited excellent inhibition activities against weed root growth. In addition to this study using 3-(Trifluoromethyl)-1H-pyrazole, there are many other studies that have used 3-(Trifluoromethyl)-1H-pyrazole(cas: 20154-03-4Recommanded Product: 20154-03-4<\/a>) was used in this study.<\/p>\n

3-(Trifluoromethyl)-1H-pyrazole(cas: 20154-03-4) belongs to pyrazoles. Pyrazole derivatives have been reported to exhibit a wide range of applications in medicinal chemistry and pharmacology. A large number of drugs incorporating pyrazole structure have been utilized as partial agonists for nicotinic acid receptors, antidepressants, antimicrobial agents, antiviral agents, and antifungal agents solely or along with the combination of other structural motifs.Recommanded Product: 20154-03-4<\/a><\/p>\n

Referemce:
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

3-(Trifluoromethyl)-1H-pyrazole(cas: 20154-03-4) belongs to pyrazoles. Pyrazole derivatives have been reported to exhibit a wide range of applications in medicinal chemistry and pharmacology. A large number of drugs incorporating pyrazole structure have been utilized as partial agonists for nicotinic acid receptors, antidepressants, antimicrobial agents, antiviral agents, and antifungal agents solely or along with the combination of other structural motifs.Recommanded Product: 20154-03-4<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[205,131],"tags":[128],"class_list":["post-10411","post","type-post","status-publish","format-standard","hentry","category-20154-03-4","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"\nMa, Hong-Ju's team published research in Pest Management Science in 2015 | CAS: 20154-03-4 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Recommanded Product: 20154-03-4In 2015 ,\u300aDesign, synthesis and herbicidal evaluation of novel 4-(1H-pyrazol-1-yl)pyrimidine derivatives\u300b appeared in Pest Management Science. 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