{"id":10280,"date":"2022-10-20T01:52:11","date_gmt":"2022-10-19T17:52:11","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=10280"},"modified":"2022-10-20T01:52:11","modified_gmt":"2022-10-19T17:52:11","slug":"kobe-jozes-team-published-research-in-journal-of-heterocyclic-chemistry-in-1974-54346-19-9","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=10280","title":{"rendered":"Kobe, Joze&#8217;s team published research in Journal of Heterocyclic Chemistry  in 1974 | 54346-19-9"},"content":{"rendered":"<p>Kobe, Joze; Robins, Roland K.; O&#8217;Brien, Darrell E. published the artcile< Synthesis and chemical reactions of certain pyrazolo[1,5-a]-1,3,5-triaziness>,  <a href=\"https:\/\/www.ambeed.com\/products\/54346-19-9.html\">Product Details of C6H5ClN4S<\/a>,  the main research area is  pyrazolotriazine; adenine analog pyrazolotriazine; hypoxanthine analog pyrazolotriazine; xanthine analog pyrazolotriazine; substitution pyrazolotriazine.<\/p>\n<p>3-Aminopyrazole was used to prepare pyrazolo[1,5-a]-1,3,5-triazines. 4-Chloro-2-methylthiopyrazolo[1,5-a]-1,3,5-triazine was prepared and used for studies of nucleophilic displacement reactions; both the Cl and MeS groups may be displaced by nucleophiles. Adenine, hypoxanthine, and xanthine analogs of the pyrazolo[1,5-a]-1,3,5-triazine ring were prepared similarly. Electrophilic substitution occurs at C-8. The Me group was introduced at C-4 by a novel ring opening and closing of the triazine ring.<\/p>\n<p>Journal of Heterocyclic Chemistry published new progress about Substitution reaction. 54346-19-9 belongs to class pyrazoles-derivatives, and the molecular formula is C6H5ClN4S, <a href=\"https:\/\/www.ambeed.com\/products\/54346-19-9.html\">Product Details of C6H5ClN4S<\/a>.<\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Journal of Heterocyclic Chemistry published new progress about Substitution reaction. 54346-19-9 belongs to class pyrazoles-derivatives, and the molecular formula is C6H5ClN4S, <a href=\"https:\/\/www.ambeed.com\/products\/54346-19-9.html\">Product Details of C6H5ClN4S<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[751,131],"tags":[716],"class_list":["post-10280","post","type-post","status-publish","format-standard","hentry","category-54346-19-9","category-pyrazoles-derivatives","tag-m-w200-250"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Kobe, Joze&#039;s team published research in Journal of Heterocyclic Chemistry in 1974 | 54346-19-9 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Kobe, Joze; Robins, Roland K.; O&#039;Brien, Darrell E. published the artcile&lt; Synthesis and chemical reactions of certain pyrazolo[1,5-a]-1,3,5-triaziness&gt;, Product Details of C6H5ClN4S, the main research area is pyrazolotriazine; adenine analog pyrazolotriazine; hypoxanthine analog pyrazolotriazine; xanthine analog pyrazolotriazine; substitution pyrazolotriazine.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=10280\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Kobe, Joze&#039;s team published research in Journal of Heterocyclic Chemistry in 1974 | 54346-19-9 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Kobe, Joze; Robins, Roland K.; O&#039;Brien, Darrell E. published the artcile&lt; Synthesis and chemical reactions of certain pyrazolo[1,5-a]-1,3,5-triaziness&gt;, Product Details of C6H5ClN4S, the main research area is pyrazolotriazine; 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Robins, Roland K.; O'Brien, Darrell E. published the artcile< Synthesis and chemical reactions of certain pyrazolo[1,5-a]-1,3,5-triaziness>, Product Details of C6H5ClN4S, the main research area is pyrazolotriazine; adenine analog pyrazolotriazine; hypoxanthine analog pyrazolotriazine; xanthine analog pyrazolotriazine; substitution pyrazolotriazine.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10280#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=10280\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10280#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Kobe, Joze&#8217;s team published research in Journal of Heterocyclic Chemistry in 1974 | 54346-19-9\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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