{"id":10267,"date":"2022-10-19T01:47:22","date_gmt":"2022-10-18T17:47:22","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=10267"},"modified":"2022-10-19T01:47:22","modified_gmt":"2022-10-18T17:47:22","slug":"neunhoeffer-hanss-team-published-research-in-liebigs-annalen-der-chemie-in-1993-cas-15366-34-4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=10267","title":{"rendered":"Neunhoeffer, Hans&#8217;s team published research in Liebigs Annalen der Chemie in 1993 | CAS: 15366-34-4"},"content":{"rendered":"<p>\u300a1,2,3-Triazines. IV. Synthesis of 1,2,3-triazinecarboxylates\u300b was written by Neunhoeffer, Hans; Bopp, Ralf; Diehl, Werner. <a href=\"https:\/\/www.ambeed.com\/products\/15366-34-4.html\">Safety of Methyl 1H-pyrazole-3-carboxylate<\/a>This research focused ontriazine preparation; triazinecarboxylate preparation; rearrangement cyclopropenyl azide; pyrazolotriazinone preparation; ring expansion pyrazolamine alkoxycarbonyl; aminopyrazole alkoxycarbonyl ring enlargement. The article conveys some information:<\/p>\n<p>Some 1,2,3-triazinecarboxylates I ((R = Me, ethyl; R1 = aryl; R2 = aryl, trimethylsilyl) were prepared by rearrangement of intermediate (alkoxycarbonyl)cyclopropenyl azides II (same R, R1, R2) as well as by oxidation of 1-aminopyrazoles. Reaction of 1-aminopyrazole-5-carboxylates with tri-Et orthoformate and ammonia gave pyrazolo[3,2-f][1,2,4]triazin-4-ones. The results came from multiple reactions, including the reaction of Methyl 1H-pyrazole-3-carboxylate(cas: 15366-34-4<a href=\"https:\/\/www.ambeed.com\/products\/15366-34-4.html\">Safety of Methyl 1H-pyrazole-3-carboxylate<\/a>)<\/p>\n<p>Methyl 1H-pyrazole-3-carboxylate(cas: 15366-34-4) belongs to pyrazoles. Pyrazole derivatives have been reported to exhibit a wide range of applications in medicinal chemistry and pharmacology. A large number of drugs incorporating pyrazole structure have been utilized as partial agonists for nicotinic acid receptors, antidepressants, antimicrobial agents, antiviral agents, and antifungal agents solely or along with the combination of other structural motifs.<a href=\"https:\/\/www.ambeed.com\/products\/15366-34-4.html\">Safety of Methyl 1H-pyrazole-3-carboxylate<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Methyl 1H-pyrazole-3-carboxylate(cas: 15366-34-4) belongs to pyrazoles. Pyrazole derivatives have been reported to exhibit a wide range of applications in medicinal chemistry and pharmacology. A large number of drugs incorporating pyrazole structure have been utilized as partial agonists for nicotinic acid receptors, antidepressants, antimicrobial agents, antiviral agents, and antifungal agents solely or along with the combination of other structural motifs.<a href=\"https:\/\/www.ambeed.com\/products\/15366-34-4.html\">Safety of Methyl 1H-pyrazole-3-carboxylate<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[174,131],"tags":[128],"class_list":["post-10267","post","type-post","status-publish","format-standard","hentry","category-15366-34-4","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Neunhoeffer, Hans&#039;s team published research in Liebigs Annalen der Chemie in 1993 | CAS: 15366-34-4 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"\u300a1,2,3-Triazines. IV. Synthesis of 1,2,3-triazinecarboxylates\u300b was written by Neunhoeffer, Hans; Bopp, Ralf; Diehl, Werner. Safety of Methyl 1H-pyrazole-3-carboxylateThis research focused ontriazine preparation; triazinecarboxylate preparation; rearrangement cyclopropenyl azide; pyrazolotriazinone preparation; ring expansion pyrazolamine alkoxycarbonyl; aminopyrazole alkoxycarbonyl ring enlargement. The article conveys some information:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=10267\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Neunhoeffer, Hans&#039;s team published research in Liebigs Annalen der Chemie in 1993 | CAS: 15366-34-4 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"\u300a1,2,3-Triazines. IV. Synthesis of 1,2,3-triazinecarboxylates\u300b was written by Neunhoeffer, Hans; Bopp, Ralf; Diehl, Werner. Safety of Methyl 1H-pyrazole-3-carboxylateThis research focused ontriazine preparation; triazinecarboxylate preparation; rearrangement cyclopropenyl azide; pyrazolotriazinone preparation; ring expansion pyrazolamine alkoxycarbonyl; aminopyrazole alkoxycarbonyl ring enlargement. 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IV. Synthesis of 1,2,3-triazinecarboxylates\u300b was written by Neunhoeffer, Hans; Bopp, Ralf; Diehl, Werner. Safety of Methyl 1H-pyrazole-3-carboxylateThis research focused ontriazine preparation; triazinecarboxylate preparation; rearrangement cyclopropenyl azide; pyrazolotriazinone preparation; ring expansion pyrazolamine alkoxycarbonyl; aminopyrazole alkoxycarbonyl ring enlargement. 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