{"id":10263,"date":"2022-10-19T01:47:22","date_gmt":"2022-10-18T17:47:22","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=10263"},"modified":"2022-10-19T01:47:22","modified_gmt":"2022-10-18T17:47:22","slug":"alam-khyaruls-team-published-research-in-advanced-synthesis-catalysis-in-2016-cas-80537-07-1","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=10263","title":{"rendered":"Alam, Khyarul&#8217;s team published research in Advanced Synthesis &#038; Catalysis in 2016 | CAS: 80537-07-1"},"content":{"rendered":"<p>In 2016,Advanced Synthesis &#038; Catalysis included an article by Alam, Khyarul; Kim, Seong Min; Kim, Do Joong; Park, Jin Kyoon. <a href=\"https:\/\/www.ambeed.com\/products\/80537-07-1.html\">Application of 80537-07-1<\/a>. The article was titled \u300aDevelopment of Structurally Diverse N-Heterocyclic Carbene Ligands via Palladium-Copper-Catalyzed Decarboxylative Arylation of Pyrazolo[1,5-a]pyridine-3-carboxylic Acid\u300b. The information in the text is summarized as follows:<\/p>\n<p>A series of fused non-classical normal N-heterocyclic carbenes, Pyrpy-NHC precursors derived from pyrazolo[1,5-a]pyridines, has been prepared using palladium-copper-catalyzed decarboxylative arylation of pyrazolo[1,5-a]pyridine-3-carboxylic acid. Air-stable palladium and rhodium complexes of these ligands have been synthesized via mild transmetalation of Ag-Pyrpy-NHC. The structural properties of Rh(Pyrpy-NHC)(COD)Cl complexes were determined via X-ray anal. The measurement of the CO stretching frequencies of dicarbonyl Rh-Pyrpy-NHC complexes revealed that the electron donating strength of Pyrpy-NHC could be tuned by varying the substituents of the aryl group. A catalytic study of the Pd-Pyrpy-NHC complexes revealed promising activity in the Suzuki-Miyaura reaction under ambient atm. conditions. The experimental part of the paper was very detailed, including the reaction process of 2-Phenylpyrazolo[1,5-a]pyridine-3-carboxylic acid(cas: 80537-07-1<a href=\"https:\/\/www.ambeed.com\/products\/80537-07-1.html\">Application of 80537-07-1<\/a>)<\/p>\n<p>2-Phenylpyrazolo[1,5-a]pyridine-3-carboxylic acid(cas: 80537-07-1) belongs to pyrazoles. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, antipyretic, neuroleptic, anticonvulsant, antiarrhythmic, sedative, muscle relaxant, monoamine oxidase inhibitory, anti-inflammatory,  antidiabetic and antibacterial activities. <a href=\"https:\/\/www.ambeed.com\/products\/80537-07-1.html\">Application of 80537-07-1<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>2-Phenylpyrazolo[1,5-a]pyridine-3-carboxylic acid(cas: 80537-07-1) belongs to pyrazoles. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, antipyretic, neuroleptic, anticonvulsant, antiarrhythmic, sedative, muscle relaxant, monoamine oxidase inhibitory, anti-inflammatory,  antidiabetic and antibacterial activities. <a href=\"https:\/\/www.ambeed.com\/products\/80537-07-1.html\">Application of 80537-07-1<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[756,131],"tags":[129],"class_list":["post-10263","post","type-post","status-publish","format-standard","hentry","category-80537-07-1","category-pyrazoles-derivatives","tag-200-300"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Alam, Khyarul&#039;s team published research in Advanced Synthesis &amp; Catalysis in 2016 | CAS: 80537-07-1 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"In 2016,Advanced Synthesis &amp; Catalysis included an article by Alam, Khyarul; Kim, Seong Min; Kim, Do Joong; Park, Jin Kyoon. Application of 80537-07-1. The article was titled \u300aDevelopment of Structurally Diverse N-Heterocyclic Carbene Ligands via Palladium-Copper-Catalyzed Decarboxylative Arylation of Pyrazolo[1,5-a]pyridine-3-carboxylic Acid\u300b. The information in the text is summarized as follows:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=10263\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Alam, Khyarul&#039;s team published research in Advanced Synthesis &amp; Catalysis in 2016 | CAS: 80537-07-1 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"In 2016,Advanced Synthesis &amp; Catalysis included an article by Alam, Khyarul; Kim, Seong Min; Kim, Do Joong; Park, Jin Kyoon. Application of 80537-07-1. The article was titled \u300aDevelopment of Structurally Diverse N-Heterocyclic Carbene Ligands via Palladium-Copper-Catalyzed Decarboxylative Arylation of Pyrazolo[1,5-a]pyridine-3-carboxylic Acid\u300b. 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Application of 80537-07-1. The article was titled \u300aDevelopment of Structurally Diverse N-Heterocyclic Carbene Ligands via Palladium-Copper-Catalyzed Decarboxylative Arylation of Pyrazolo[1,5-a]pyridine-3-carboxylic Acid\u300b. 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Application of 80537-07-1. The article was titled \u300aDevelopment of Structurally Diverse N-Heterocyclic Carbene Ligands via Palladium-Copper-Catalyzed Decarboxylative Arylation of Pyrazolo[1,5-a]pyridine-3-carboxylic Acid\u300b. The information in the text is summarized as follows:","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=10263","og_locale":"en_US","og_type":"article","og_title":"Alam, Khyarul's team published research in Advanced Synthesis & Catalysis in 2016 | CAS: 80537-07-1 | pyrazoles-derivatives","og_description":"In 2016,Advanced Synthesis & Catalysis included an article by Alam, Khyarul; Kim, Seong Min; Kim, Do Joong; Park, Jin Kyoon. Application of 80537-07-1. 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