{"id":10176,"date":"2022-10-17T09:11:19","date_gmt":"2022-10-17T01:11:19","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=10176"},"modified":"2022-10-17T09:11:19","modified_gmt":"2022-10-17T01:11:19","slug":"micheli-fabrizios-team-published-research-in-bioorganic-medicinal-chemistry-in-2011-cas-20154-03-4","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=10176","title":{"rendered":"Micheli, Fabrizio&#8217;s team published research in Bioorganic &#038; Medicinal Chemistry in 2011 | CAS: 20154-03-4"},"content":{"rendered":"<p>In 2011,Micheli, Fabrizio; Cavanni, Paolo; Bettati, Michela; Bonanomi, Giorgio; Di Fabio, Romano; Fazzolari, Elettra; Marchioro, Carla; Roscic, Maja; Tarsi, Luca; Visentini, Filippo; Zonzini, Laura; Worby, Angela published \u300a1-Heteroaryl-6-(3,4-dichlorophenyl)-3-azabicyclo[4.1.0]heptane: Further insights into a class of triple re-uptake inhibitors\u300b.Bioorganic &#038; Medicinal Chemistry published the findings.<a href=\"https:\/\/www.ambeed.com\/products\/20154-03-4.html\">Recommanded Product: 3-(Trifluoromethyl)-1H-pyrazole<\/a> The information in the text is summarized as follows:<\/p>\n<p>Further exploration around the recently disclosed potent triple re-uptake inhibitor 6-(3,4-dichlorophenyl)-1-[(methyloxy)methyl]-3-azabicyclo[4.1.0]heptane led to the identification of a new series of potent triple re-uptake inhibitors endowed with good developability characteristics. The insertion of a further aryl moiety into the template allowed the titration&#8217; of the SERT\/NET\/DAT ratio leading to the identification of further tools in this important area. In the part of experimental materials, we found many familiar compounds, such as 3-(Trifluoromethyl)-1H-pyrazole(cas: 20154-03-4<a href=\"https:\/\/www.ambeed.com\/products\/20154-03-4.html\">Recommanded Product: 3-(Trifluoromethyl)-1H-pyrazole<\/a>)<\/p>\n<p>3-(Trifluoromethyl)-1H-pyrazole(cas: 20154-03-4) belongs to pyrazoles. Pyrazole derivatives have been reported to exhibit a wide range of applications in medicinal chemistry and pharmacology. A large number of drugs incorporating pyrazole structure have been utilized as partial agonists for nicotinic acid receptors, antidepressants, antimicrobial agents, antiviral agents, and antifungal agents solely or along with the combination of other structural motifs.<a href=\"https:\/\/www.ambeed.com\/products\/20154-03-4.html\">Recommanded Product: 3-(Trifluoromethyl)-1H-pyrazole<\/a><\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>3-(Trifluoromethyl)-1H-pyrazole(cas: 20154-03-4) belongs to pyrazoles. Pyrazole derivatives have been reported to exhibit a wide range of applications in medicinal chemistry and pharmacology. A large number of drugs incorporating pyrazole structure have been utilized as partial agonists for nicotinic acid receptors, antidepressants, antimicrobial agents, antiviral agents, and antifungal agents solely or along with the combination of other structural motifs.<a href=\"https:\/\/www.ambeed.com\/products\/20154-03-4.html\">Recommanded Product: 3-(Trifluoromethyl)-1H-pyrazole<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[205,131],"tags":[128],"class_list":["post-10176","post","type-post","status-publish","format-standard","hentry","category-20154-03-4","category-pyrazoles-derivatives","tag-100-200"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Micheli, Fabrizio&#039;s team published research in Bioorganic &amp; Medicinal Chemistry in 2011 | CAS: 20154-03-4 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"In 2011,Micheli, Fabrizio; Cavanni, Paolo; Bettati, Michela; Bonanomi, Giorgio; Di Fabio, Romano; Fazzolari, Elettra; Marchioro, Carla; Roscic, Maja; Tarsi, Luca; Visentini, Filippo; Zonzini, Laura; Worby, Angela published \u300a1-Heteroaryl-6-(3,4-dichlorophenyl)-3-azabicyclo[4.1.0]heptane: Further insights into a class of triple re-uptake inhibitors\u300b.Bioorganic &amp; Medicinal Chemistry published the findings.Recommanded Product: 3-(Trifluoromethyl)-1H-pyrazole The information in the text is summarized as follows:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=10176\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Micheli, Fabrizio&#039;s team published research in Bioorganic &amp; Medicinal Chemistry in 2011 | CAS: 20154-03-4 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"In 2011,Micheli, Fabrizio; Cavanni, Paolo; Bettati, Michela; Bonanomi, Giorgio; Di Fabio, Romano; Fazzolari, Elettra; Marchioro, Carla; Roscic, Maja; Tarsi, Luca; Visentini, Filippo; Zonzini, Laura; Worby, Angela published \u300a1-Heteroaryl-6-(3,4-dichlorophenyl)-3-azabicyclo[4.1.0]heptane: Further insights into a class of triple re-uptake inhibitors\u300b.Bioorganic &amp; Medicinal Chemistry published the findings.Recommanded Product: 3-(Trifluoromethyl)-1H-pyrazole The information in the text is summarized as follows:\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=10176\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-10-17T01:11:19+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10176\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10176\",\"name\":\"Micheli, Fabrizio's team published research in Bioorganic & Medicinal Chemistry in 2011 | CAS: 20154-03-4 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-10-17T01:11:19+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"In 2011,Micheli, Fabrizio; 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