{"id":1009,"date":"2020-11-12T10:53:29","date_gmt":"2020-11-12T02:53:29","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=1009"},"modified":"2020-11-12T10:53:29","modified_gmt":"2020-11-12T02:53:29","slug":"brief-introduction-of-1-methyl-1h-pyrazole-5-carbaldehyde","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=1009","title":{"rendered":"Brief introduction of 1-Methyl-1H-pyrazole-5-carbaldehyde"},"content":{"rendered":"

Adding a certain compound to certain chemical reactions, such as: 27258-33-9, name is 1-Methyl-1H-pyrazole-5-carbaldehyde, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 27258-33-9, 27258-33-9<\/a><\/p>\n

General procedure: Method B [34]: The reaction mixture of aldehyde (4 mmol), acetone (116 mg, 2 mmol) and K2CO3 (1.1 g, 4 mmol) in the mixed solvent of toluene-ethanol-water (10 mL 4.0 mL 2.0 mL) was stirred at 70 C for 12 h. After cooling down to room temperature, the solvent was evaporated in vacuo. The resulting residue was partitioned between dichloromethane and water. The aqueous phase was further extracted with dichloromethane twice. The combined organic extracts were rinsed with brine and dried over anhydrous magnesium sulfate. The organic solvent was removed under vacuum to give a residue, which was purified by preparativeTLC (5% methanol in dichloromethane) or column chromatography(2% methanol in dichloromethane).<\/p>\n

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Methyl-1H-pyrazole-5-carbaldehyde, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"excerpt":{"rendered":"

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Methyl-1H-pyrazole-5-carbaldehyde, other downstream synthetic routes, hurry up and to see.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[160,131],"tags":[126],"class_list":["post-1009","post","type-post","status-publish","format-standard","hentry","category-27258-33-9","category-pyrazoles-derivatives","tag-m-w100-200"],"yoast_head":"\nBrief introduction of 1-Methyl-1H-pyrazole-5-carbaldehyde<\/title>\n<meta name=\"description\" content=\"Adding a certain compound to certain chemical reactions, such as: 27258-33-9, name is 1-Methyl-1H-pyrazole-5-carbaldehyde, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 27258-33-9, 27258-33-9\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=1009\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Brief introduction of 1-Methyl-1H-pyrazole-5-carbaldehyde\" \/>\n<meta property=\"og:description\" content=\"Adding a certain compound to certain chemical reactions, such as: 27258-33-9, name is 1-Methyl-1H-pyrazole-5-carbaldehyde, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/en.cravatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Brief introduction of 1-Methyl-1H-pyrazole-5-carbaldehyde","description":"Adding a certain compound to certain chemical reactions, such as: 27258-33-9, name is 1-Methyl-1H-pyrazole-5-carbaldehyde, belongs to pyrazoles-derivatives compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. 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