{"id":10049,"date":"2022-10-14T03:55:15","date_gmt":"2022-10-13T19:55:15","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=10049"},"modified":"2022-10-14T03:55:15","modified_gmt":"2022-10-13T19:55:15","slug":"haydl-alexander-ms-team-published-research-in-angewandte-chemie-international-edition-in-2015-13808-65-6","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=10049","title":{"rendered":"Haydl, Alexander M&#8217;s team published research in Angewandte Chemie, International Edition  in 2015 | 13808-65-6"},"content":{"rendered":"<p>Haydl, Alexander M.; Xu, Kun; Breit, Bernhard published the artcile< Regio- and Enantioselective Synthesis of N-Substituted Pyrazoles by Rhodium-Catalyzed Asymmetric Addition to Allenes>,  <a href=\"https:\/\/www.ambeed.com\/products\/13808-65-6.html\">Application In Synthesis of  13808-65-6<\/a>,  the main research area is  pyrazole terminal alkene addition rhodium catalyst; allylated pyrazole asym preparation; allenes; allylic compounds; asymmetric catalysis; heterocycles; rhodium.<\/p>\n<p>The rhodium-catalyzed asym. N-selective coupling of pyrazole derivatives with terminal allenes gives access to enantioenriched secondary and tertiary allylic pyrazoles, i.e. I, which can be employed for the synthesis of medicinally important targets. The reaction tolerates a large variety of functional groups and labeling experiments gave insights into the reaction mechanism. This new methodol. was further applied in a highly efficient synthesis of JAK 1\/2 inhibitor (R)-ruxolitinib.<\/p>\n<p>Angewandte Chemie, International Edition published new progress about Addition reaction catalysts, stereoselective. 13808-65-6 belongs to class pyrazoles-derivatives, and the molecular formula is C9H7BrN2, <a href=\"https:\/\/www.ambeed.com\/products\/13808-65-6.html\">Application In Synthesis of  13808-65-6<\/a>.<\/p>\n<p>Referemce:<br \/><a href=\"https:\/\/en.wikipedia.org\/wiki\/Pyrazole\">Pyrazole &#8211; Wikipedia<\/a>,<br \/><a href=\"https:\/\/www.sciencedirect.com\/topics\/chemistry\/pyrazoles\">Pyrazoles &#8211; an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Angewandte Chemie, International Edition published new progress about Addition reaction catalysts, stereoselective. 13808-65-6 belongs to class pyrazoles-derivatives, and the molecular formula is C9H7BrN2, <a href=\"https:\/\/www.ambeed.com\/products\/13808-65-6.html\">Application In Synthesis of  13808-65-6<\/a>.<\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[480,131],"tags":[716],"class_list":["post-10049","post","type-post","status-publish","format-standard","hentry","category-13808-65-6","category-pyrazoles-derivatives","tag-m-w200-250"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v24.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Haydl, Alexander M&#039;s team published research in Angewandte Chemie, International Edition in 2015 | 13808-65-6 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"Haydl, Alexander M.; Xu, Kun; Breit, Bernhard published the artcile&lt; Regio- and Enantioselective Synthesis of N-Substituted Pyrazoles by Rhodium-Catalyzed Asymmetric Addition to Allenes&gt;, Application In Synthesis of 13808-65-6, the main research area is pyrazole terminal alkene addition rhodium catalyst; allylated pyrazole asym preparation; allenes; allylic compounds; asymmetric catalysis; heterocycles; rhodium.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=10049\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Haydl, Alexander M&#039;s team published research in Angewandte Chemie, International Edition in 2015 | 13808-65-6 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"Haydl, Alexander M.; Xu, Kun; Breit, Bernhard published the artcile&lt; Regio- and Enantioselective Synthesis of N-Substituted Pyrazoles by Rhodium-Catalyzed Asymmetric Addition to Allenes&gt;, Application In Synthesis of 13808-65-6, the main research area is pyrazole terminal alkene addition rhodium catalyst; allylated pyrazole asym preparation; allenes; allylic compounds; asymmetric catalysis; heterocycles; rhodium.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=10049\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-10-13T19:55:15+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10049\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10049\",\"name\":\"Haydl, Alexander M's team published research in Angewandte Chemie, International Edition in 2015 | 13808-65-6 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-10-13T19:55:15+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"Haydl, Alexander M.; Xu, Kun; Breit, Bernhard published the artcile< Regio- and Enantioselective Synthesis of N-Substituted Pyrazoles by Rhodium-Catalyzed Asymmetric Addition to Allenes>, Application In Synthesis of 13808-65-6, the main research area is pyrazole terminal alkene addition rhodium catalyst; allylated pyrazole asym preparation; allenes; allylic compounds; asymmetric catalysis; heterocycles; rhodium.\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10049#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=10049\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10049#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Haydl, Alexander M&#8217;s team published research in Angewandte Chemie, International Edition in 2015 | 13808-65-6\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. 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