{"id":10019,"date":"2022-10-13T03:04:34","date_gmt":"2022-10-12T19:04:34","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=10019"},"modified":"2022-10-13T03:04:34","modified_gmt":"2022-10-12T19:04:34","slug":"goble-stephen-d-s-team-published-research-in-bioorganic-medicinal-chemistry-letters-in-2010-cas-474432-62-7","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=10019","title":{"rendered":"Goble, Stephen D.’s team published research in Bioorganic & Medicinal Chemistry Letters in 2010 | CAS: 474432-62-7"},"content":{"rendered":"

HPLC of Formula: 474432-62-7<\/a>On March 15, 2010, Goble, Stephen D.; Wang, Liping; Howell, K. Lulu; Bansal, Alka; Berger, Richard; Brockunier, Linda; Di Salvo, Jerry; Feighner, Scott; Harper, Bart; He, Jiafang; Hurley, Amanda; Hreniuk, Donna; Parmee, Emma; Robbins, Michael; Salituro, Gino; Sanfiz, Anthony; Streckfuss, Eric; Watkins, Eloisa; Weber, Ann E.; Struthers, Mary; Edmondson, Scott D. published an article in Bioorganic & Medicinal Chemistry Letters. The article was \u300aHeterocyclic acetamide and benzamide derivatives as potent and selective \u03b23-adrenergic receptor agonists with improved rodent pharmacokinetic profiles\u300b. The article mentions the following:<\/p>\n

A series of amide derived \u03b23-adrenergic receptor (AR) agonists is described. The discovery and optimization of several series of compounds derived from 1 (I), is used to lay the SAR foundation for second generation \u03b23-AR agonists for the treatment of overactive bladder. In addition to this study using Pyrazolo[1,5-a]pyridine-7-carboxylic acid, there are many other studies that have used Pyrazolo[1,5-a]pyridine-7-carboxylic acid(cas: 474432-62-7HPLC of Formula: 474432-62-7<\/a>) was used in this study.<\/p>\n

Pyrazolo[1,5-a]pyridine-7-carboxylic acid(cas: 474432-62-7) belongs to pyrazoles. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, antipyretic, neuroleptic, anticonvulsant, antiarrhythmic, sedative, muscle relaxant, monoamine oxidase inhibitory, anti-inflammatory, antidiabetic and antibacterial activities. HPLC of Formula: 474432-62-7<\/a><\/p>\n

Referemce:
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

Pyrazolo[1,5-a]pyridine-7-carboxylic acid(cas: 474432-62-7) belongs to pyrazoles. Pyrazoles are commonly used scaffold molecules in drug discovery projects. The use of pyrazole derivatives is based on their analgesic, antipyretic, neuroleptic, anticonvulsant, antiarrhythmic, sedative, muscle relaxant, monoamine oxidase inhibitory, anti-inflammatory, antidiabetic and antibacterial activities. 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