{"id":10000,"date":"2022-10-13T03:03:51","date_gmt":"2022-10-12T19:03:51","guid":{"rendered":"https:\/\/www.pyrazoles-derivatives.com\/?p=10000"},"modified":"2022-10-13T03:03:51","modified_gmt":"2022-10-12T19:03:51","slug":"lakhey-nivruttis-team-published-research-in-journal-of-chemical-technology-and-biotechnology-in-2020-cas-930-36-9","status":"publish","type":"post","link":"https:\/\/www.pyrazoles-derivatives.com\/?p=10000","title":{"rendered":"Lakhey, Nivrutti’s team published research in Journal of Chemical Technology and Biotechnology in 2020 | CAS: 930-36-9"},"content":{"rendered":"

\u300aToxicity of azoles towards the anaerobic ammonium oxidation (anammox) process\u300b was written by Lakhey, Nivrutti; Li, Guangbin; Sierra-Alvarez, Reyes; Field, Jim A.. Computed Properties of C4H6N2<\/a> And the article was included in Journal of Chemical Technology and Biotechnology on April 30 ,2020. The article conveys some information:<\/p>\n

Azoles are an important class of compounds that are widely used as corrosion inhibitors in aircraft de-icing agents, cooling towers, semiconductor manufacturing and household dishwashing detergents. They also are important moieties in pharmaceutical drugs and fungicides. Azoles are widespread emerging contaminants occurring frequently in water bodies. Azole compounds can potentially cause inhibition towards key biol. processes in natural ecosystems and wastewater treatment processes. Of particular concern is the inhibition of azoles to the nitrification process (aerobic oxidation of ammonium). This study investigated the acute toxicity of azole compounds towards the anaerobic ammonia oxidation (anammox) process, which is an important environmental biotechnol. gaining traction for nutrient-nitrogen removal during wastewater treatment. In this study, using batch bioassay techniques, the anammox toxicity of eight commonly occurring azole compounds was evaluated. The results show that 1H-benzotriazole and 5-methyl-1H-benzotriazole had the highest inhibitory effect on the anammox process, causing 50% decrease in anammox activity (IC50) at concentrations of 19.6 and 17.8 mg L-1, resp. 1H-imidazole caused less severe toxicity with an IC50 of 79.4 mg L-1. The other azole compounds were either nontoxic (1H-pyrazole, 1H-1,2,4-triazole and 1-methyl-pyrazole) or at best mildly toxic (1H-benzotriazole-5-carboxylic acid and 3,5-dimethyl-1H-pyrazole) towards the anammox bacteria at the concentrations tested. This study showed that most azole compounds tested displayed mild to low or no toxicity towards the anammox bacteria. The anammox bacteria were found to be far less sensitive to azoles compared to nitrifying bacteria.1-Methylpyrazole(cas: 930-36-9Computed Properties of C4H6N2<\/a>) was used in this study.<\/p>\n

1-Methylpyrazole(cas: 930-36-9) belongs to pyrazoles. Pyrazole derivatives have been reported to exhibit a wide range of applications in medicinal chemistry and pharmacology. A large number of drugs incorporating pyrazole structure have been utilized as partial agonists for nicotinic acid receptors, antidepressants, antimicrobial agents, antiviral agents, and antifungal agents solely or along with the combination of other structural motifs.Computed Properties of C4H6N2<\/a><\/p>\n

Referemce:
Pyrazole – Wikipedia<\/a>,
Pyrazoles – an overview | ScienceDirect Topics<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

1-Methylpyrazole(cas: 930-36-9) belongs to pyrazoles. Pyrazole derivatives have been reported to exhibit a wide range of applications in medicinal chemistry and pharmacology. A large number of drugs incorporating pyrazole structure have been utilized as partial agonists for nicotinic acid receptors, antidepressants, antimicrobial agents, antiviral agents, and antifungal agents solely or along with the combination of other structural motifs.Computed Properties of C4H6N2<\/a><\/p>\n","protected":false},"author":8,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[245,131],"tags":[743],"class_list":["post-10000","post","type-post","status-publish","format-standard","hentry","category-930-36-9","category-pyrazoles-derivatives","tag-0-100"],"yoast_head":"\nLakhey, Nivrutti's team published research in Journal of Chemical Technology and Biotechnology in 2020 | CAS: 930-36-9 | pyrazoles-derivatives<\/title>\n<meta name=\"description\" content=\"\u300aToxicity of azoles towards the anaerobic ammonium oxidation (anammox) process\u300b was written by Lakhey, Nivrutti; Li, Guangbin; Sierra-Alvarez, Reyes; Field, Jim A.. Computed Properties of C4H6N2 And the article was included in Journal of Chemical Technology and Biotechnology on April 30 ,2020. The article conveys some information:\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.pyrazoles-derivatives.com\/?p=10000\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Lakhey, Nivrutti's team published research in Journal of Chemical Technology and Biotechnology in 2020 | CAS: 930-36-9 | pyrazoles-derivatives\" \/>\n<meta property=\"og:description\" content=\"\u300aToxicity of azoles towards the anaerobic ammonium oxidation (anammox) process\u300b was written by Lakhey, Nivrutti; Li, Guangbin; Sierra-Alvarez, Reyes; Field, Jim A.. Computed Properties of C4H6N2 And the article was included in Journal of Chemical Technology and Biotechnology on April 30 ,2020. The article conveys some information:\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.pyrazoles-derivatives.com\/?p=10000\" \/>\n<meta property=\"og:site_name\" content=\"pyrazoles-derivatives\" \/>\n<meta property=\"article:published_time\" content=\"2022-10-12T19:03:51+00:00\" \/>\n<meta name=\"author\" content=\"Jessica.F\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Jessica.F\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10000\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10000\",\"name\":\"Lakhey, Nivrutti's team published research in Journal of Chemical Technology and Biotechnology in 2020 | CAS: 930-36-9 | pyrazoles-derivatives\",\"isPartOf\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\"},\"datePublished\":\"2022-10-12T19:03:51+00:00\",\"author\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\"},\"description\":\"\u300aToxicity of azoles towards the anaerobic ammonium oxidation (anammox) process\u300b was written by Lakhey, Nivrutti; Li, Guangbin; Sierra-Alvarez, Reyes; Field, Jim A.. Computed Properties of C4H6N2 And the article was included in Journal of Chemical Technology and Biotechnology on April 30 ,2020. The article conveys some information:\",\"breadcrumb\":{\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10000#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/www.pyrazoles-derivatives.com\/?p=10000\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/?p=10000#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"\u9996\u9875\",\"item\":\"https:\/\/www.pyrazoles-derivatives.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Lakhey, Nivrutti’s team published research in Journal of Chemical Technology and Biotechnology in 2020 | CAS: 930-36-9\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#website\",\"url\":\"https:\/\/www.pyrazoles-derivatives.com\/\",\"name\":\"pyrazoles-derivatives\",\"description\":\"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1\",\"name\":\"Jessica.F\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g\",\"caption\":\"Jessica.F\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Lakhey, Nivrutti's team published research in Journal of Chemical Technology and Biotechnology in 2020 | CAS: 930-36-9 | pyrazoles-derivatives","description":"\u300aToxicity of azoles towards the anaerobic ammonium oxidation (anammox) process\u300b was written by Lakhey, Nivrutti; Li, Guangbin; Sierra-Alvarez, Reyes; Field, Jim A.. Computed Properties of C4H6N2 And the article was included in Journal of Chemical Technology and Biotechnology on April 30 ,2020. The article conveys some information:","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.pyrazoles-derivatives.com\/?p=10000","og_locale":"en_US","og_type":"article","og_title":"Lakhey, Nivrutti's team published research in Journal of Chemical Technology and Biotechnology in 2020 | CAS: 930-36-9 | pyrazoles-derivatives","og_description":"\u300aToxicity of azoles towards the anaerobic ammonium oxidation (anammox) process\u300b was written by Lakhey, Nivrutti; Li, Guangbin; Sierra-Alvarez, Reyes; Field, Jim A.. Computed Properties of C4H6N2 And the article was included in Journal of Chemical Technology and Biotechnology on April 30 ,2020. The article conveys some information:","og_url":"https:\/\/www.pyrazoles-derivatives.com\/?p=10000","og_site_name":"pyrazoles-derivatives","article_published_time":"2022-10-12T19:03:51+00:00","author":"Jessica.F","twitter_card":"summary_large_image","twitter_misc":{"Written by":"Jessica.F","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=10000","url":"https:\/\/www.pyrazoles-derivatives.com\/?p=10000","name":"Lakhey, Nivrutti's team published research in Journal of Chemical Technology and Biotechnology in 2020 | CAS: 930-36-9 | pyrazoles-derivatives","isPartOf":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#website"},"datePublished":"2022-10-12T19:03:51+00:00","author":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1"},"description":"\u300aToxicity of azoles towards the anaerobic ammonium oxidation (anammox) process\u300b was written by Lakhey, Nivrutti; Li, Guangbin; Sierra-Alvarez, Reyes; Field, Jim A.. Computed Properties of C4H6N2 And the article was included in Journal of Chemical Technology and Biotechnology on April 30 ,2020. The article conveys some information:","breadcrumb":{"@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=10000#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.pyrazoles-derivatives.com\/?p=10000"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/www.pyrazoles-derivatives.com\/?p=10000#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"\u9996\u9875","item":"https:\/\/www.pyrazoles-derivatives.com\/"},{"@type":"ListItem","position":2,"name":"Lakhey, Nivrutti’s team published research in Journal of Chemical Technology and Biotechnology in 2020 | CAS: 930-36-9"}]},{"@type":"WebSite","@id":"https:\/\/www.pyrazoles-derivatives.com\/#website","url":"https:\/\/www.pyrazoles-derivatives.com\/","name":"pyrazoles-derivatives","description":"Several pyrazole derivatives possess important pharmacological activities and they have been proved useful materials in drug research. Pyrazole derivatives play an important role in antitumor agents.","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.pyrazoles-derivatives.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/d9a9f27bed675392c6f363a01ffd49f1","name":"Jessica.F","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/www.pyrazoles-derivatives.com\/#\/schema\/person\/image\/","url":"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","contentUrl":"https:\/\/weavatar.com\/avatar\/2d1cec2a99eeaad5a5b217c9cdbfb610?s=96&d=mm&r=g","caption":"Jessica.F"}}]}},"_links":{"self":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/10000","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=10000"}],"version-history":[{"count":0,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=\/wp\/v2\/posts\/10000\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=10000"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=10000"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pyrazoles-derivatives.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=10000"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}