Tag: M.W=0-100

Name: 3,5-Dimethyl-1H-pyrazole. In 2020.0 MOL CATAL published article about HIGHLY EFFICIENT SYNTHESIS; X-RAY STRUCTURE; BENZOFURAN DERIVATIVES; ARYLBORONIC ACIDS; ROOM-TEMPERATURE; WATER OXIDATION; PHENOLS; LIGAND; COMPLEXES; ETHYLENE in [Marais, Lindie; Vosloo, Hermanus C. M.; Swarts, Andrew J.] North West Univ, Focus Area Chem Resource Beneficiat, Catalysis & Synth Res Grp, 11 Hoffman St, ZA-2520 Potchefstroom, South Africa in 2020.0, Cited 49.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.

A catalyst system comprising of pyrazolylpyridineamine/Cu(I)/CsOH is reported. for the hydroxylation of aryl iodides and bromides with moderate to outstanding yields, without the use of an inert atmosphere. A comprehensive parameter optimisation study established optimum component concentrations: [Cu(MeCN)(4)]BF4 and 2-(1H-pyrazol-1-yl)-N-(pyridine-2-ylmethyl)ethan-1-amine (L01) (2 mol %), substrate (1 mmol), CsOH (4 mmol) and DMSO:H2O (1:1, 3 mL). Monitoring substrate conversion as a function of time revealed an induction period of 90 min, which could be eliminated through the initial in situ formation of the proposed [(L01)Cu-OH] intermediate. Eliminating the induction period resulted in complete conversion within one hour, with turnover numbers exceeding that of the benchmark catalyst system operating at an optimal catalyst loading of 0.05 mol %.

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Pyrazole – Wikipedia,
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An article Effective and Reversible Carbon Dioxide Insertion into Cerium Pyrazolates WOS:000510194800001 published article about METAL-ORGANIC FRAMEWORK; CYCLOHEXENE OXIDE; ALTERNATING COPOLYMERIZATION; REDUCTIVE DISPROPORTIONATION; STRUCTURAL-CHARACTERIZATION; BETA-DIKETIMINATO; CYCLIC CARBONATES; CO2 INSERTION; COMPLEXES; CAPTURE in [Bayer, Uwe; Werner, Daniel; Maichle-Moessmer, Caecilia; Anwander, Reiner] Eberhard Karls Univ Tubingen, Inst Anorgan Chem, Morgenstelle 18, D-72076 Tubingen, Germany in 2020.0, Cited 90.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. Category: pyrazoles-derivatives

The homoleptic pyrazolate complexes [Ce-4(III)(Me(2)pz)(12)] and [Ce-IV(Me(2)pz)(4)](2) quantitatively insert CO2 to give [Ce-4(III)(Me(2)pzCO(2))(12)] and [Ce-IV(Me(2)pzCO(2))(4)], respectively (Me(2)pz=3,5-dimethylpyrazolato). This process is reversible for both complexes, as observed by in situ IR and NMR spectroscopy in solution and by TGA in the solid state. By adjusting the molar ratio, one molecule of CO2 per [Ce-IV(Me(2)pz)(4)] complex could be inserted to give trimetallic [Ce-3(Me(2)pz)(9)(Me(2)pzCO(2))(3)(thf)]. Both the cerous and ceric insertion products catalyze the formation of cyclic carbonates from epoxides and CO2 under mild conditions. In the absence of epoxide, the ceric catalyst is prone to reduction by the co-catalyst tetra-n-butylammonium bromide (TBAB).

Welcome to talk about 67-51-6, If you have any questions, you can contact Bayer, U; Werner, D; Maichle-Mossmer, C; Anwander, R or send Email.. Category: pyrazoles-derivatives

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Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

I found the field of Materials Science very interesting. Saw the article Tumor microenvironment and NIR laser dual-responsive release of berberine 9-O-pyrazole alkyl derivative loaded in graphene oxide nanosheets for chemo-photothermal synergetic cancer therapy published in 2020.0. Application In Synthesis of 3,5-Dimethyl-1H-pyrazole, Reprint Addresses Liu, YF (corresponding author), Cent South Univ, Coll Chem & Chem Engn, Dept Pharmaceut Engn, Changsha 410083, Hunan, Peoples R China.; Liu, ZB (corresponding author), Cent South Univ, Xiangya Sch Pharmaceut Sci, 172 Tongzipo Rd, Changsha 410013, Hunan, Peoples R China.; Liu, ZB (corresponding author), Cent South Univ, Mol Imaging Res Ctr, Changsha 410008, Hunan, Peoples R China.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole

A berberine 9-O-pyrazole alkyl derivative, a chemical compound (called B3) previously synthesized by our group, shows anti-cancer activity. However, B3 lacks targeting cytotoxicity to cancer cells, leading to obvious toxic side effects on normal cells. To solve this problem, here, we prepared a drug delivery system, namely, AS1411-GO/B3 for tumor targeting, in which nano-graphene oxide (GO) sheets were employed as the drug carrier, and the aptamer AS1411 was conjugated onto GO for tumor targeting. GO also had a photothermal effect, which helped the release of B3 from GO as well as the thermal cytotoxicity to cells. We found that the release of B3 could respond to acid conditions, indicating that the tumor intracellular environment could promote the release of B3, thus allowing it to perform chemotherapy effects. This system could also release B3 in response to photothermal heating, moreover, combined photothermal therapy and chemotherapy to improve the anticancer activity was achieved. This AS1411-GO/B3 platform with chemo-photothermal synergetic therapy provides a very promising treatment for tumors.

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Pyrazole – Wikipedia,
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Product Details of 67-51-6. Authors Horiuchi, S; Tanaka, S; Moon, S; Sakuda, E; Ito, A; Arikawa, Y; Umakoshi, K in AMER CHEMICAL SOC published article about in [Horiuchi, Shinnosuke; Tanaka, Seiya; Moon, Sangjoon; Sakuda, Eri; Arikawa, Yasuhiro; Umakoshi, Keisuke] Nagasaki Univ, Grad Sch Engn, Div Chem & Mat Sci, Nagasaki 8528521, Japan; [Ito, Akitaka] Kochi Univ Technol, Grad Sch Engn, Kami, Kochi 7821502, Japan in 2021.0, Cited 52.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6

The synthesis and photophysical properties of the heteropolynuclear Pt-Ag complex having cyclometalated rollover bipyridine ligands (bpy*) and bridging pyrazolato ligands are reported. The Pt2Ag2 complex was synthesized by two step reactions from a Pt(II) complex precursor having the rollover bpy* ligand, [Pt(bpy*)(dmso)Cl], with 3,5-dimethylpyrazole (Me(2)pzH) and a subsequent replacement of NH protons in the Me(2)pzH moieties with the Ag(I) ion. The Pt2Ag2 complex exists as a mixture of U- and Z-shaped isomers in solution, whose structures were clearly determined by single-crystal X-ray structural analyses. NMR studies using the single crystals revealed rapid isomerization of the Pt2Ag2 complexes in solution, although the Pt2Ag2 structures were supported effectively by the multiple metal-metal interactions. Furthermore, the Pt2Ag2 framework can capture a Ag(I) ion during the U-Z isomerization to afford a Pt2Ag3 core with the formation of Pt. Ag dative bonds. The Pt2Ag3 complex showed further aggregation to form a dimer structure in the presence of coordinating solvent via the crystallization process. The formation of Pt. Ag dative bonds significantly changes the emission energy from the Pt2Ag2 complex, while the emission spectra of U- and Z-isomers of Pt2Ag2 complex almost coincide with each other and their emissive properties are very similar. The density functional theory (DFT) and time-dependent DFT (TD-DFT) calculations revealed the effects of additional Ag(I) ion on the photophysical properties of the heteropolynuclear Pt-Ag complexes bearing the rollover bpy* ligands.

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Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

I found the field of Chemistry; Materials Science very interesting. Saw the article Recovery of scratch deformation formed on crosslinked polyorganosiloxane films published in 2019.0. Category: pyrazoles-derivatives, Reprint Addresses Kumano, N (corresponding author), Toyota Cent Res & Dev Labs Inc, Nagakute, Aichi 4801192, Japan.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole

As consumers generally desire longer lasting scratch-free coatings, scratch resistance has become one of the most important properties of automotive coatings. Surface scratches that deform a coating but do not break it can recover over time, eventually even becoming invisible to the human eye. This phenomenon arises from elastic plastic behavior and is called self-recover?. This paper mainly focuses on the recovery of scratch deformations. Conventional coatings with low glass transition temperature (Tg) have fast recovery characteristics, like rubbers, but cannot attain sufficient hardness. Therefore, it is difficult to simultaneously improve both scratch recovery characteristics and hardness in conventional coatings such as 2 K urethane coatings consisting of acrylic polyols because both arise from the same causes as the mobility of the main chain of the coating. Herein, we explore the remarkable improvement of scratch recovery characteristics without sacrificing hardness by using a base resin with a siloxane main chain instead of a carbon-carbon main chain such as that of an acrylic polyol. We demonstrate that crosslinked polyorganosilsesquioxane coatings (Si-films) achieve both hardness suitable for automobile coatings and improved scratch recovery characteristics superior to those of conventional coatings (C-films). Si-films demonstrated 20% better elastic recovery index than C-films, and the Si-films recovered about twice as fast as the C-films. Scratch deformations on the Si-films almost disappeared after 15 min, even at room temperature, while C-films were needed over 24 days. Thus, coatings based on a siloxane main chain may offer dramatically improved self-recovery.

Category: pyrazoles-derivatives. Welcome to talk about 67-51-6, If you have any questions, you can contact Kumano, N; Mori, K; Kato, M or send Email.

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Pyrazole – Wikipedia,
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Authors Zhang, FL; Zhou, PC; Zhang, SL; Li, YY; Zhang, QF; Guo, WL; Huang, J; Wang, WY; Dong, Z; Wei, B; Wei, DH; Cao, GX; Zhai, B in ELSEVIER published article about in [Zhang, Fuli; Zhang, Shulin; Li, Yuanyang; Zhang, Quanfeng; Guo, Wenlong; Huang, Jing; Wang, Wenyu; Dong, Zhen; Cao, Guangxiu; Zhai, Bin] Shangqiu Normal Univ, Coll Chem & Chem Engn, Engn Tech Res Ctr Optoelect Funct Mat Henan Prov, Key Lab Biomol Recognit & Sensing Henan Prov, Shangqiu 476000, Peoples R China; [Zhou, Pengchao; Wei, Bin] Shanghai Univ, Sch Mechatron Engn & Automat, Key Lab Adv Display & Syst Applicat, Minist Educ, Shanghai 200072, Peoples R China; [Wei, Donghui] Zhengzhou Univ, Coll Chem & Mol Engn, Zhengzhou 450001, Peoples R China in 2021.0, Cited 66.0. HPLC of Formula: C5H8N2. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6

In this work, we report three deep-blue emitting cationic iridium complexes Ir1-Ir3 with 2′,6′-difluoro-2,3′-bipyridine cyclometalated ligand and pyrazole-type ancillary ligands. Synthesis, crystal structure, photophysical and electrochemical properties of Ir1-Ir3 are studied in detail. Ir1-Ir3 exhibit efficient phosphorescence emissions at 439, 438 and 437 nm with CIE 1931 coordinates of (0.14, 0.12), (0.14, 0.12) and (0.14, 0.13), and luminescence quantum yields of 0.35, 0.27 and 0.50 in CH2Cl2 solutions, respectively, which are among the highest levels of ever reported cationic iridium(III) complexes emitting deep-blue light. High luminescence quantum yields, excellent color purity and short lifetimes demonstrates the great potential of Ir1-Ir3 for lightemitting electrochemical cells (LECs) and solution-processable organic light-emitting diodes (OLEDs) as efficient blue emitters.

Welcome to talk about 67-51-6, If you have any questions, you can contact Zhang, FL; Zhou, PC; Zhang, SL; Li, YY; Zhang, QF; Guo, WL; Huang, J; Wang, WY; Dong, Z; Wei, B; Wei, DH; Cao, GX; Zhai, B or send Email.. HPLC of Formula: C5H8N2

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Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Product Details of 67-51-6. I found the field of Chemistry; Crystallography very interesting. Saw the article Nickel (II) and cobalt (II) complexes with bidentate nitrogen-sulfur donor pyrazole derivative ligands: Syntheses, characterization, X-ray structure, electrochemical studies, and antibacterial activity published in 2020.0, Reprint Addresses Soltani, B (corresponding author), Azarbaijan Shahid Madani Univ, Fac Sci, Dept Chem, POB 53714-161, Tabriz, Iran.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole.

The synthesis, characterization, antibacterial activity and cyclic voltammetry of bidentate N,S donor pyrazole derivative ligands abbreviated as Na(EtNCSPz) (1), Na(PhNCSPz) (2), Na(PhNCSPz(me2)) (3), Na (PhNCSPz(me3)) (4) and their metal complexes with Ni(II) and Co(II) metal ions are reported, where Pz = pyrazole, Pz(me2) = 3,5-dimethylpyrazole and Pz(me3) = 3,4,5-trimethylpyrazole. All of the synthesized ligands and complexes have been characterized by physicochemical and spectroscopic methods and the crystal structures of [Ni(EtNCSPz)(2)] (1a) and [Ni(PhNCSPz(Me3))(2)] (4a) have been determined by X-ray diffraction analysis. The X-ray crystal structure of both the complexes describe a square planar coordination geometry. The electrochemical studies show that the synthesized complex is an electrochemically active species, furthermore, substitution electron donating groups on the ligands shift the reduction and oxidation potentials to negative values. Antibacterial activity results indicate these complexes possess high activity against gram-positive and gram-negative bacteria compare to the free ligands. (C) 2020 Elsevier Ltd. All rights reserved.

Welcome to talk about 67-51-6, If you have any questions, you can contact Soltani, B; Ghorbanpour, M; Ziegler, CJ; Ebadi-Nahari, M; Mohammad-Rezaei, R or send Email.. Product Details of 67-51-6

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Pyrazole – Wikipedia,
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Safety of 3,5-Dimethyl-1H-pyrazole. Fosu, SC; Hambira, CM; Chen, AD; Fuchs, JR; Nagib, DA in [Fosu, Stacy C.; Chen, Andrew D.; Nagib, David A.] Ohio State Univ, Dept Chem & Biochem, Columbus, OH 43210 USA; [Hambira, Chido M.; Fuchs, James R.] Ohio State Univ, Coll Pharm, Div Med Chem & Pharmacognosy, Columbus, OH 43210 USA published Site-Selective C-H Functionalization of (Hetero)Arenes via Transient, Non-symmetric lodanes in 2019.0, Cited 51.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.

A strategy for C-H functionalization of arenes and heteroarenes has been developed to allow site-selective incorporation of various anions, including Cl, Br, OMs, OTs, and OTf. This approach is enabled by in situ generation of reactive, non-symmetric iodanes by combining anions and bench-stable Phl(OAc)(2). The utility of this mechanism is demonstrated via para-selective chlorination of medicinally relevant arenes, as well as site-selective C-H chlorination of heteroarenes. Spectroscopic, computational, and competition experiments describe the unique nature, reactivity, and selectivity of these transient, unsymmetrical iodanes.

Safety of 3,5-Dimethyl-1H-pyrazole. Bye, fridends, I hope you can learn more about C5H8N2, If you have any questions, you can browse other blog as well. See you lster.

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An article 1,6-Aza-Michael addition of para-quinone methides with N-heterocycles catalyzed by Zn(OTf)(2): A regioselective approach to N-diarylmethyl-substituted heterocycles WOS:000546923400005 published article about ASYMMETRIC 1,6-CONJUGATE ADDITION; AZA-MICHAEL ADDITION; STEREOSELECTIVE-SYNTHESIS; COUPLING REACTIONS; EASY ACCESS; CARBAZOLES; 1,6-HYDROPHOSPHONYLATION; ADDITION/AROMATIZATION; 1,6-ADDITION; ALKYLATION in [Guin, Soumitra; Saha, Hemonta K.; Patel, Ashvani K.; Gudimella, Santosh K.; Biswas, Subhankar; Samanta, Sampak] Indian Inst Technol Indore, Discipline Chem, Simrol 453552, Madhya Pradesh, India in 2020.0, Cited 77.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. Formula: C5H8N2

An efficient Zn(OTf)(2)-catalyzed regioselective C-N bond making reaction between a bunch of aryl/heteroaryl-substituted para-quinone methides as ideal 1,6-acceptors and various aromatic/non-aromatic aza-heterocycles bearing N-H moiety namely carbazoles, pyrazoles, indazole, benzotriazole and saccharin is reported. This 1,6-aza-Michael technique delivers predominantly NI-diarylmethyl-substituted heterocyclic scaffolds bearing a valuable phenolic moiety in good to high yields with an excellent regioselectivity. Furthermore, this LUMO lowering catalytic system allows different kinds of useful functionalities and excels with broad substrates under mild conditions. Importantly, our control experiments suggested that N2-adducts of indazole, benzotriazole and 3-methyl pyrazole as minor isomers were progressively converted into N1-adducts during the reaction via a retro-aza-Michael reaction triggered by Zn(OTf)(2), offering excellent regioselectivities of the products. (C) 2020 Elsevier Ltd. All rights reserved.

Welcome to talk about 67-51-6, If you have any questions, you can contact Guin, S; Saha, HK; Patel, AK; Gudimella, SK; Biswas, S; Samanta, S or send Email.. Formula: C5H8N2

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Authors Paudel, J; Pokhrel, A; Kirk, ML; Li, FF in AMER CHEMICAL SOC published article about ELECTRONIC-STRUCTURE CONTRIBUTIONS; SULFITE OXIDASE; ACTIVE-SITE; DIOXOMOLYBDENUM(VI) COMPLEXES; DIOXO-MO(VI) COMPLEX; DIOXYGEN ACTIVATION; CRYSTAL-STRUCTURE; CIS-DIOXO; LIGANDS; MODEL in [Paudel, Jaya; Li, Feifei] New Mexico State Univ, Dept Chem & Biochem, Las Cruces, NM 88003 USA; [Pokhrel, Amrit; Kirk, Martin L.] Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA in 2019.0, Cited 89.0. Quality Control of 3,5-Dimethyl-1H-pyrazole. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6

We report the syntheses, crystal structures, and characterization of the novel cis-dioxomolybdenum(VI) complexes [Tpm*(MoO2Cl)-O-VI](MoO2Cl3) (1) and [Tpm*(MoO2Cl)-O-VI](ClO4) (2), which are supported by the charge-neutral tris(3,5-dimethyl-1-pyrazolyl)methane (Tpm*) ligand. A comparison between isostructural [Tpm*(MoO2Cl)-O-VI](+) and Tp*(MoO2Cl)-O-VI [Tp* = hydrotris(3,5-dimethyl-1-pyrazolyl)borate] reveals the effects of one unit of overall charge difference on their spectroscopic and electrochemical properties, geometric and electronic structures, and O-atom-transfer (OAT) reactivities, providing new insight into pyranopterin molybdoenzyme OAT reactivity. Computational studies of these molecules indicate that the delocalized positive charge lowers the lowest unoccupied molecular orbital (LUMO) energy of cationic [Tpm*MoO2Cl](+) relative to Tp*MoO2Cl. Despite their virtually identical geometric structures revealed by crystal structures, the Mo-VI/Mo-V redox potential of 2 is increased by 350 mV relative to that of Tp*(MoO2Cl)-O-VI. This LUMO stabilization also contributes to an increased effective electrophilicity of [Tp*MoO2Cl](+) relative to that of Tp*MoO2Cl, resulting in a more favorable resonant interaction between the molydenum complex LUMO and the highest occupied molecular orbital (HOMO) of the PPh3 substrate. This leads to a greater thermodynamic driving force, an earlier transition state, and a lowered activation barrier for the orbitally controlled first step of the OAT reaction in the Tpm* system relative to the Tp* system. An Eyring plot analysis shows that this initial step yields an O Mo-IV-OPPh3 intermediate via an associative transition state, and the reaction is similar to 500-fold faster for 2 than for Tp*MoO2Cl. The second step of the OAT reaction entails solvolysis of the O Mo-IV-OPPh3 intermediate to afford the solvent-substituted Mo-IV product and is 750-fold faster for the Tpm* system at -15 degrees C compared to the Tp* system. The observed rate enhancement for the second step is ascribed to a switch of the reaction mechanism from a dissociative pathway for the Tp* system to an alternative associative pathway for the Tpm* system. This is due to a more Lewis acidic Mo-IV center in the Tpm* system.

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Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics