Month: April 2022

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Catalytic nucleophilic activation of acetonitrile via a cooperative catalysis of cationic Ru complex, DBU, and NaPF6, published in 2007-08-27, which mentions a compound: 17190-29-3, Name is 3-Hydroxy-3-phenylpropanenitrile, Molecular C9H9NO, Recommanded Product: 17190-29-3.

The development of an efficient catalytic system for the direct addition of acetonitrile under mild amine basic conditions is described. A cooperative catalysis of CpRu complex, DBU, and NaPF6 enables chemoselective and catalytic generation of nucleophiles from barely acidic acetonitrile, which is integrated into the addition to aldehydes, imines, and activated ketones. Mechanistic investigations revealed that the three catalyst components work together to achieve high catalytic efficiency.

There are many compounds similar to this compound(17190-29-3)Recommanded Product: 17190-29-3. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Highly regioselective conversion of epoxides to β-hydroxy nitriles using metal(II) Schiff base complexes as new catalysts under mild conditions, published in 2013-01-25, which mentions a compound: 17190-29-3, mainly applied to hydroxy nitrile preparation; regioselective ring opening epoxide metal Schiff base catalyst, COA of Formula: C9H9NO.

Epoxides undergo efficient ring opening with potassium cyanide in acetonitrile in the presence of metal Schiff base complexes as catalysts. This method was carried out under neutral and mild conditions with both high yields and high regioselectivity within a short period of time. Thus, several β-hydroxy nitriles, useful intermediates for the synthesis of biol. active mols., were easily obtained at room temperature

There are many compounds similar to this compound(17190-29-3)COA of Formula: C9H9NO. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Kitson, Russell R. A.; Moody, Christopher J. published an article about the compound: (1,10-Phenanthroline)(trifluoromethyl)copper(I)( cas:1300746-79-5,SMILESS:F[C-](F)([Cu+]1[N]2=C3C4=[N]1C=CC=C4C=CC3=CC=C2)F ).Electric Literature of C13H8CuF3N2. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:1300746-79-5) through the article.

The toxicity associated with the geldanamycin (I) family of benzoquinone ansamycins when used as heat shock protein-90 inhibitor mol. therapeutics is ameliorated by substitution at the 19-position. The resulting 19-substituted derivatives have greater potential for success in oncol. clin. trials and for other medicinal purposes such as the treatment of neurodegenerative conditions. Having overcome hurdles associated with the sensitivity and complexity of these mols., through a variety of synthetic approaches, the synthesis of a series of 19-substituted geldanamycin derivatives is reported herein using optimized Stille and Suzuki coupling reactions. Further compounds were accessible via copper-mediated coupling and nucleophilic addition reactions. He new compounds are of significant medicinal interest, in view of their significantly reduced toxicity previously observed for this class of substrate compared to their 19-unsubstituted counterparts that have been evaluated in the clinic.

There are many compounds similar to this compound(1300746-79-5)Electric Literature of C13H8CuF3N2. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Nickel-Catalyzed Ligand-Free Hiyama Coupling of Aryl Bromides and Vinyltrimethoxysilane, published in 2021-10-31, which mentions a compound: 52287-51-1, Name is 6-Bromo-2,3-dihydrobenzo[b][1,4]dioxine, Molecular C8H7BrO2, Formula: C8H7BrO2.

Authors herein disclose the first Ni-catalyzed Hiyama coupling of aryl halides with vinylsilanes. This protocol uses cheap, nontoxic, and stable vinyltrimethoxysilane as the vinyl donor, proceeds under mild and ligand-free conditions, furnishing a diverse variety of styrene derivatives in high yields with excellent functional group compatibility.

There are many compounds similar to this compound(52287-51-1)Formula: C8H7BrO2. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Korsager, Signe; Taaning, Rolf H.; Lindhardt, Anders T.; Skrydstrup, Troels published the article 《Reductive Carbonylation of Aryl Halides Employing a Two-Chamber Reactor: A Protocol for the Synthesis of Aryl Aldehydes Including 13C- and D-Isotope Labeling》. Keywords: palladium catalyst reductive carbonylation aryl iodide bromide fluorenecarbonyl chloride; isotope labeling aryl aldehyde.They researched the compound: 6-Bromo-2,3-dihydrobenzo[b][1,4]dioxine( cas:52287-51-1 ).HPLC of Formula: 52287-51-1. Aromatic heterocyclic compounds can be divided into two categories: single heterocyclic and fused heterocyclic. In addition, there is a lot of other information about this compound (cas:52287-51-1) here.

A protocol has been developed for conducting the palladium-catalyzed reductive carbonylation of aryl iodides and bromides using 9-methylfluorene-9-carbonyl chloride (COgen) as a source of externally delivered carbon monoxide in a sealed two-chamber system (COware), and potassium formate as the in situ hydride source. The method is tolerant to a wide number of functional groups positioned on the aromatic ring, and it can be exploited for the isotope labeling of the aldehyde group. Hence, reductive carbonylations run with 13COgen provide a facile access to 13C-labeled aromatic aldehydes, whereas with DCO2K, the aldehyde is specifically labeled with deuterium. Two examples of double isotopic labeling are also demonstrated. Finally, the method was applied to the specific carbon-13 labeling of the β-amyloid binding compound, florbetaben.

There are many compounds similar to this compound(52287-51-1)HPLC of Formula: 52287-51-1. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 3-Hydroxy-3-phenylpropanenitrile( cas:17190-29-3 ) is researched.Recommanded Product: 17190-29-3.Jinzaki, Takaaki; Arakawa, Mitsuru; Kinoshita, Hidenori; Ichikawa, Junji; Miura, Katsukiyo published the article 《Nucleophilic Addition of α-(Dimethylsilyl)nitriles to Aldehydes and Ketones》 about this compound( cas:17190-29-3 ) in Organic Letters. Keywords: beta hydroxynitrile preparation alpha dimethylsilylnitrile aldehyde ketone nucleophilic addition; nucleophilic addition dimethylsilylnitrile metal salt promoter catalyst. Let’s learn more about this compound (cas:17190-29-3).

α-Alkylated (dimethylsilyl)acetonitriles (Me2HSiCR3R4CN) react spontaneously with aldehydes in DMSO to give β-hydroxynitriles in good to high yields. The addition to ketones is effectively promoted by using MgCl2 or CaCl2. (Dimethylsilyl)acetonitrile (Me2HSiCH2CN) shows lower reactivity than the α-alkylated analogs. However, the parent reagent adds efficiently to aldehydes and ketones under catalysis by AcOLi or MgCl2.

There are many compounds similar to this compound(17190-29-3)Recommanded Product: 17190-29-3. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Recommanded Product: 3-Hydroxy-3-phenylpropanenitrile. Aromatic heterocyclic compounds can also be classified according to the number of heteroatoms contained in the heterocycle: single heteroatom, two heteroatoms, three heteroatoms and four heteroatoms. Compound: 3-Hydroxy-3-phenylpropanenitrile, is researched, Molecular C9H9NO, CAS is 17190-29-3, about The Knoevenagel reaction in electrochemically activated solvents. Author is Feroci, M.; Orsini, M.; Sotgiu, G.; Inesi, A..

The electrochem. activation of organic solvents HS (CH3CN, CH3CH2CN, DMF, DMSO) containing Et4NPF6 as supporting electrolyte (i.e. their electrolysis under galvanostatic control) allows to induce in these solutions, in the absence of any catalyst, the Knoevenagel condensation between CH-acid CH2(CN)2 (1) and carbonylic substrates. Reaction products were isolated in good yields 97-48%. The progress of the Knoevenagel condensation is affected by Q (number of Faradays per mol of 1 supplied to the electrodes) and, moderately, by the nature of the solvents. The rates of the single steps are compared by elementary voltammetric anal.

There are many compounds similar to this compound(17190-29-3)Recommanded Product: 3-Hydroxy-3-phenylpropanenitrile. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Enhancing Reaction Kinetics of Sulfur-Containing Species in Li-S Batteries by Quantum Dot-Level Tin Oxide Hydroxide Catalysts, published in 2021-05-24, which mentions a compound: 814-94-8, mainly applied to reaction kinetic sulfur lithium battery quantum dot catalyst, COA of Formula: C2O4Sn.

The application of Li-S batteries is hampered by some unresolved issues, including the severe polysulfides shuttle effects and sluggish reaction kinetics. Hence, we designed and prepared tin oxide hydroxide quantum dots (TOH) anchored on a honeycomb porous carbon (HPC) matrix as multifunctional sulfur hosts, and deeply studied the enhancement of TOH on the reaction kinetics of Li-S battery referred to as the apparent activation energy, Li+ ion diffusion coefficient, and reaction barrier. It is proved by d. functional theory that the HPC@TOH hosts have a higher binding energy to polysulfides than the simplex carbon matrix. Meanwhile, the catalytic TOH can decrease the surface active energy of the redox reaction and accelerate the conversion of sulfur-containing species. Consequently, by means of the synergistic effects of phys. capture and chem. adsorption together with catalytic conversion, the comprehensive performances of Li-S batteries are distinctly promoted. In particular, a Li-S battery using HPC@TOH as a host delivers a good reversible specific capacity of 1342.95 mAh g-1 at 0.1 C. Moreover, with the current increased to 1 C, it shows a relatively satisfactory specific capacity of 918.05 mAh g-1. After 400 cycles, a competitive specific capacity of 688.54 mAh g-1 can still be maintained with a very low fading rate of 0.06% per cycle. Most importantly, when the sulfur area loading reaches as high as 4.25 mg cm-2 and electrolyte/sulfur ratio is controlled to be as low as 7μL mg-1, and the Li-S battery using HPC @TOH as a host can still cycle steadily more than 50 cycles at 0.2 C. Therefore, this work provides an effective manner to boost the comprehensive performance of Li-S batteries by virtue of optimizing and designing the host material with synergistic effects of phys. capture, chem. adsorption, and catalytic conversion.

There are many compounds similar to this compound(814-94-8)COA of Formula: C2O4Sn. if you want to know more, you can check out my other articles. I hope it will help you，maybe you’ll find some useful information.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: (1,10-Phenanthroline)(trifluoromethyl)copper(I)( cas:1300746-79-5 ) is researched.Product Details of 1300746-79-5.Dibrell, Sara E.; Maser, Michael R.; Reisman, Sarah E. published the article 《SeO2-Mediated Oxidative Transposition of Pauson-Khand Products》 about this compound( cas:1300746-79-5 ) in Journal of the American Chemical Society. Keywords: bicyclic cyclopentenone oxidative transposition selenium dioxide mediated. Let’s learn more about this compound (cas:1300746-79-5).

Oxidative transpositions of bicyclic cyclopentenones I [R1 = Me, Ph, n-hexyl, 3-pyridyl, etc.; R2 = H, Me; R3 = H, Me, Ph; R32 = (CH2)5, CH2CH2NBocCH2CH2; X = O, NBoc, C(CO2Et)2, C(CO2i-Pr)2] mediated by selenium dioxide (SeO2) has been disclosed. Treatment of Pauson-Khand (PKR) reaction products I with SeO2 in the presence or absence of water furnished the corresponding di- and trioxidized cyclopentenones II and III [from I (R2 = H)], resp. Mechanistic investigations revealed multiple competing oxidation pathways that depend on substrate identity and water concentration Functionalization of the oxidized products via cross-coupling methods demonstrated their synthetic utility. These transformations allows rapid access to oxidatively transposed cyclopentenones from simple PKR products.

I hope my short article helps more people learn about this compound((1,10-Phenanthroline)(trifluoromethyl)copper(I))Product Details of 1300746-79-5. Apart from the compound(1300746-79-5), you can read my other articles to know other related compounds.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 6-Bromo-2,3-dihydrobenzo[b][1,4]dioxine(SMILESS: BrC1=CC=C2OCCOC2=C1,cas:52287-51-1) is researched.Synthetic Route of C4H6O4Pd. The article 《Synthesis of Axially Chiral 2,2′-Bisphosphobiarenes via a Nickel-Catalyzed Asymmetric Ullmann Coupling: General Access to Privileged Chiral Ligands without Optical Resolution》 in relation to this compound, is published in Journal of the American Chemical Society. Let’s take a look at the latest research on this compound (cas:52287-51-1).

The authors report an asym. homocoupling of ortho-(iodo)arylphosphine oxides and ortho-(iodo)arylphosphonates resulting in highly enantioenriched axially chiral bisphosphine oxides and bisphosphonates. These products are readily converted to enantioenriched biaryl bisphosphines without need for chiral auxiliaries or optical resolution This provides a practical route for the development of previously unstudied atroposelective biaryl bisphosphine ligands. The conditions also proved effective for asym. dimerization of other, nonphosphorus-containing aryl halides.

I hope my short article helps more people learn about this compound(6-Bromo-2,3-dihydrobenzo[b][1,4]dioxine)COA of Formula: C8H7BrO2. Apart from the compound(52287-51-1), you can read my other articles to know other related compounds.

Reference:
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics