Category: 14580-22-4

Malik, G. M. published the artcileSynthesis, characterization and dyeing properties of mono azo pyrazolone dyes based on 2-amino 5-methyl thiazole, Formula: C10H9ClN2O, the publication is International Journal of Chemistry (Mumbai, India) (2015), 4(3), 284-294, database is CAplus.

Different substituted monoazo pyrazolone dyes from N⁴-(5-methyl-1,3-thiazol-2-yl)-1,3-thiazole-2,4-diamine have been synthesized. The condensation of 5-Me 2-amino thiazole with chloroacetylchloride yielded 2-chloro-N-(5- methyl-1,3-thiazol-2-yl)acetamide which was reacted with thiourea at reflux temperature using methanol and cyclized to yield N⁴-(5-methyl-1,3-thiazol-2-yl)-1,3-thiazole-2,4-diamine. This was diazotized and coupled with various substituted pyrazolones to give a new series of pyrazolone dyes, which were characterized using elemental anal., UV, IR and 1H NMR spectra. Dyeing performance and fastness properties were evaluated by applying them on nylon and polyester fabrics.

International Journal of Chemistry (Mumbai, India) published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Formula: C10H9ClN2O.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Parmar, Narsidas J. published the artcileTriethylammonium acetate-mediated domino-Knoevenagel-hetero-Diels-Alder reaction: synthesis of some angular polyheterocycles, Computed Properties of 14580-22-4, the publication is Monatshefte fuer Chemie (2013), 144(6), 865-878, database is CAplus.

A solvent-cum catalyst, ionic liquid triethylammonium acetate-mediated one-pot procedure for the synthesis of some new angular benzopyrano[3,4-c]pyrano-fused pyrazoles, e.g., I, all of which incorporate a tertiary ring junction carbon, has been developed. The stereochem. of the products has been confirmed by single-crystal X-ray diffraction data.

Monatshefte fuer Chemie published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Computed Properties of 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Parmar, Narsidas J. published the artcileSolvent-free, one-pot synthesis and biological evaluation of some new dipyrazolo [3,4-b:4′,3′-e]pyranylquinolones and their precursors, Related Products of pyrazoles-derivatives, the publication is Medicinal Chemistry Research (2014), 23(1), 42-56, database is CAplus.

One-pot synthesis of 24 new compounds, belonging to three families; dipyrazolo[3,4-b:4′,3′-e]pyranylquinolones and its precursors (pyrazolonylidene)methylquinolones and 4,4′-[(quinolinyl)methylene]bispyrazols, has been achieved in the presence of catalyst tetrabutylammonium hydrogen sulfate (TBA-HS) in solvent-free conditions. In addition to assuring chromatog.-free product isolation, this method had also allowed the reaction to proceed in a regio-selective manner provided the temperature and amount of pyrazolone are varied. At 100 °C, while 1:1 mixture of aldehyde 3 and pyrazolone 4 underwent Knoevenagel condensation, same reactants taken in ratio of 1:2 mainly domino/Knoevenagel-Michael reaction. At 120 °C, however, the domino/Knoevenagel-Michael-adducts converted into cyclized product, highlighting a new domino/Knoevenagel-Michael-cyclization synthetic sequence. The structure of all heterocycles has been confirmed by mass, IR and NMR spectral data. Based on 2D NMR NOESY experiment, it was also confirmed that the formation of only Z’ configuration of Knoevenagel alkene took place in the transformation. All are good antitubercular agents as they were found to be active against M. tuberculosis H37RV, in addition to being found active against three Gram-pos. (Streptococcus pneumoniae, Clostridium tetani, Bacillus subtilis) and three Gram-neg. (Salmonella typhi, Vibrio cholerae, Escherichia coli) bacteria, resp.

Medicinal Chemistry Research published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Related Products of pyrazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Ozaki, Toyoko published the artcileSolvent extraction of zinc with 1-(2′-chlorophenyl)-3-methyl-4-aroyl-5-pyrazolones, Safety of 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, the publication is Analytica Chimica Acta (1989), 226(1), 187-92, database is CAplus.

1-(2′-Chlorophenyl)-3-methyl-4-aroyl-5-pyrazolone derivatives were synthesized and steric effects of the 2-chlorophenyl group on the acid dissociation constants and the solvent extraction reaction of Zn were studied. Steric effects on the synergic extraction of Zn with trioctylphosphine oxide were also examined

Analytica Chimica Acta published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Safety of 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Maurya, R. C. published the artcilePreparation and characterization of some novel cyanonitrosyl {CrNO}⁵ complexes of chromium involving biologically important 2-pyrazoline-5-one derivatives, Recommanded Product: 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, the publication is National Academy Science Letters (India) (1992), 15(9), 299-301, database is CAplus.

[Cr(NO)(CN)₂(L)₂(H₂O)] (L = 1-(2′-chlorophenyl)-, 1-(4′-tolyl)-, or 1-(4′-nitrophenyl)-, and 1-(4′-sulfophenyl)-3-methyl-2-pyrazolin-5-one) were isolated as solids by the interaction of K₃[Cr(NO)(CN)₅].H₂O with L. The complexes, which were characterized by elemental anal., magnetic measurements, molar conductances, TGA, ESR and IR spectral studies, contain chromium(I) in a low-spin d⁵-configuration. An octahedral structure is proposed for the complexes.

National Academy Science Letters (India) published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Recommanded Product: 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Zhang, Xin-Ke published the artcileIodine-catalyzed oxidative annulation: facile synthesis of pyrazolooxepinopyrazolones via methyl azaarene sp³ C-H functionalization, Synthetic Route of 14580-22-4, the publication is Organic & Biomolecular Chemistry (2022), 20(6), 1236-1242, database is CAplus and MEDLINE.

An iodine-catalyzed Me azaarene sp³ C-H functionalization has been developed for the synthesis of a seven-membered O-heterocyclic architecture containing three different heterocyclic aromatic hydrocarbons. This method can be applied to a wide range of substituted Me azaarenes and diverse 2,4-dihydro-3H-pyrazol-3-ones, and brings about the efficient preparation of 2,9-dihydrooxepino[2,3-c:6,5-c’]dipyrazol-3(7H)-ones in high yields with the merits of low catalyst loading, good functional group tolerance and metal-free conditions.

Organic & Biomolecular Chemistry published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C7H10BNO3, Synthetic Route of 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Ozaki, Toyoko published the artcileSolvent extraction of zinc with 1-(2′-chlorophenyl)-3-methyl-4-aroyl-5-pyrazolones, Safety of 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, the publication is Analytica Chimica Acta (1989), 226(1), 187-92, database is CAplus.

1-(2′-Chlorophenyl)-3-methyl-4-aroyl-5-pyrazolone derivatives were synthesized and steric effects of the 2-chlorophenyl group on the acid dissociation constants and the solvent extraction reaction of Zn were studied. Steric effects on the synergic extraction of Zn with trioctylphosphine oxide were also examined

Analytica Chimica Acta published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Safety of 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Maurya, R. C. published the artcilePreparation and characterization of some novel cyanonitrosyl {CrNO}⁵ complexes of chromium involving biologically important 2-pyrazoline-5-one derivatives, Recommanded Product: 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, the publication is National Academy Science Letters (India) (1992), 15(9), 299-301, database is CAplus.

[Cr(NO)(CN)₂(L)₂(H₂O)] (L = 1-(2′-chlorophenyl)-, 1-(4′-tolyl)-, or 1-(4′-nitrophenyl)-, and 1-(4′-sulfophenyl)-3-methyl-2-pyrazolin-5-one) were isolated as solids by the interaction of K₃[Cr(NO)(CN)₅].H₂O with L. The complexes, which were characterized by elemental anal., magnetic measurements, molar conductances, TGA, ESR and IR spectral studies, contain chromium(I) in a low-spin d⁵-configuration. An octahedral structure is proposed for the complexes.

National Academy Science Letters (India) published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Recommanded Product: 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Zhang, Xin-Ke published the artcileIodine-catalyzed oxidative annulation: facile synthesis of pyrazolooxepinopyrazolones via methyl azaarene sp³ C-H functionalization, Synthetic Route of 14580-22-4, the publication is Organic & Biomolecular Chemistry (2022), 20(6), 1236-1242, database is CAplus and MEDLINE.

An iodine-catalyzed Me azaarene sp³ C-H functionalization has been developed for the synthesis of a seven-membered O-heterocyclic architecture containing three different heterocyclic aromatic hydrocarbons. This method can be applied to a wide range of substituted Me azaarenes and diverse 2,4-dihydro-3H-pyrazol-3-ones, and brings about the efficient preparation of 2,9-dihydrooxepino[2,3-c:6,5-c’]dipyrazol-3(7H)-ones in high yields with the merits of low catalyst loading, good functional group tolerance and metal-free conditions.

Organic & Biomolecular Chemistry published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C7H10BNO3, Synthetic Route of 14580-22-4.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Li, Chengxi published the artcileChemo- and regioselective defluorinative annulation of (trifluoromethyl)alkenes with pyrazolones: synthesis and insecticidal activity of 6-fluoro-1,4-dihydropyrano[2,3-c]pyrazoles, Formula: C10H9ClN2O, the publication is Organic Chemistry Frontiers (2022), 9(17), 4692-4698, database is CAplus.

The chemo- and regioselective defluorinative [3 + 3] annulation of (trifluoromethyl)alkenes and pyrazolones was reported that gives rise to various useful 6-fluoro-1,4-dihydropyrano[2,3-c]pyrazoles I [R = Ph, 4-MeC₆H₄, 4-ClC₆H₄, etc.; R¹ = Ph, 3-MeC₆H₄, 4-ClC₆H₄, etc.; R² = Me, Et, Bn, etc.] in high yields. This reaction distinguished the different nucleophilic sites of pyrazolones and featured mild conditions, a broad substrate scope, and gram-scalability. A simple derivation of the obtained 6-fluoro-1,4-dihydropyrano[2,3-c]pyrazoles efficiently afforded diverse useful compounds Significantly, compound I [R = 4-F₃CC₆H₄, R¹ = 2-ClC₆H₄, R² = Me] exhibited up to 100% insecticidal activity against Plutella xylostella, which was a destructive pest worldwide. Mechanism studies indicated that this reaction proceeded via a chemo- and regioselective S_N2’/S_NV pathway and that the double defluorinative alkylation of pyrazolones with (trifluoromethyl)alkenes was completely inhibited.

Organic Chemistry Frontiers published new progress about 14580-22-4. 14580-22-4 belongs to pyrazoles-derivatives, auxiliary class Organic Pigment, name is 1-(2-Chlorophenyl)-3-methyl-5-pyrazolone, and the molecular formula is C10H9ClN2O, Formula: C10H9ClN2O.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics