Discover the magic of the C11H12N2O

Name: 3-Methyl-1-p-tolyl-5-pyrazolone. Welcome to talk about 86-92-0, If you have any questions, you can contact Akbari, F; Didehban, K; Farhang, M or send Email.

An article Solubility of solid intermediate of pharmaceutical compounds in pure organic solvents using semi-empirical models WOS:000507620300035 published article about MAGNESIUM-DL-ASPARTATE; P-TOLUIC ACID; MIXING PROPERTIES; ACTIVITY-COEFFICIENT; NRTL-SAC; 313.15 K; PREDICTION; INGREDIENTS; PARAMETERS in [Akbari, Falamarz] Eram Inst Higher Educ, Dept Chem, POB 71957-46733, Shiraz, Iran; [Didehban, Khadijeh; Farhang, Mona] Payame Noor Univ, Dept Chem, POB 19395-3697, Tehran, Iran in 2020, Cited 35. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0. Name: 3-Methyl-1-p-tolyl-5-pyrazolone

A new semi-theoretical equation is suggested for correlation of solid-liquid solubility data with temperature. The (solid + liquid) equilibrium for Terephthaldialdehyde, 4-Nitro-o-phennylenediamine, 2,4-dihydro- 5-methyl-2(4-methylphenyl)-3H-pyrazol-3-one (also named 1-(p-toly1)-3-methyl-5pyrazolone (PTMP)), 2-Amino-5-methylthiazole and 5-chloro-1-methyl-4-nitroimidazole in 18 solvents is correlated with semi-empirical models at temperatures T = 273.15 – 318.15 K under a pressure of 101.2 kPa. Moreover, a modified Apelblat model, lambda h model, Wilson model, NRTL model, new flexible equation as Akbari, Dideban and Farhang model (ADF) and for first time the modified Scatchard-Hildebrand equation were utilized to calculate the experiment values. The performance of both ADF and modified Scatchard-Hildebrand equation have been checked by calculating the solubility data with the AARD% of 1.3808% (for 775 data points) and 0.65% (for 100 data points), respectively. The Wilson model is applied to estimate the mixing Gibbs energy, mixing enthalpy, mixing entropy, activity coefficient (ln gamma(infinity)(1)) and reduced excess enthalpy (H-I(E,infinity)) at infinitesimal concentration were calculated.

Name: 3-Methyl-1-p-tolyl-5-pyrazolone. Welcome to talk about 86-92-0, If you have any questions, you can contact Akbari, F; Didehban, K; Farhang, M or send Email.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

What Kind of Chemistry Facts Are We Going to Learn About 86-92-0

Welcome to talk about 86-92-0, If you have any questions, you can contact Wu, GX; Xu, HH; Liu, ZR; Liu, YH; Yang, X; Zhang, XL; Huang, Y or send Email.. Safety of 3-Methyl-1-p-tolyl-5-pyrazolone

An article Asymmetric Organocatalysis Combined with Palladium Catalysis: Synergistic Effect on Enantioselective Mannich/alpha-Allylation Sequential Reactions of Pyrazolones in Constructing Vicinal Quaternary Stereocenters WOS:000489200100005 published article about ALLYLIC DEAROMATIZATION REACTION; STEREOCONTROLLED CONSTRUCTION; MICHAEL ADDITION; ALKYLATION; ACID; PYRAZOLIN-5-ONES; PYRAZOL-5-ONES; ALCOHOLS; BEARING in [Wu, Gengxin; Xu, Haohan; Liu, Ziran; Liu, Yonghong; Yang, Xiang; Huang, Yan] Xinjiang Univ, Coll Chem & Chem Engn, Key Lab Oil & Gas Fine Chem, Minist Educ & Xinjiang Uyghur Autonomous Reg, Urumqi 830000, Xinjiang, Peoples R China; [Zhang, Xulong] Xinjiang Uygur Autonomous Reg Prod Qual Supervis, Urumqi 830000, Xinjiang, Peoples R China in 2019, Cited 46. Safety of 3-Methyl-1-p-tolyl-5-pyrazolone. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0

In this letter, an efficient one-pot asymmetric sequential reaction is achieved by organo/transition metal relay catalysis in constructing two consecutive C-C bonds, which involves enantioselective amino squaramide catalytic Mannich-type addition of pyrazolones to isatin-derived ketimines and a subsequent palladium catalyzed diastereoselective allylic alkylation of pyrazolones with allylic acetates. An array of novel pyrazolone-aminooxindole-propylene structural motifs are obtained in a high level of yield and with excellent enantio- and diastereoselectivity (up to 95% yield, >20:1 dr, >99% ee). This methodology features the formation of vicinal quarternary carbon-stereocenters, and the second all-carbon tetrasubstituted stereogenic center is induced by joint action of the achiral palladium catalysis and the chiral environment generated from the Mannich step. Moreover, the usefulness of this methodology is highlighted by converting the allylic product into the carbonyl compound.

Welcome to talk about 86-92-0, If you have any questions, you can contact Wu, GX; Xu, HH; Liu, ZR; Liu, YH; Yang, X; Zhang, XL; Huang, Y or send Email.. Safety of 3-Methyl-1-p-tolyl-5-pyrazolone

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Machine Learning in Chemistry about C11H12N2O

COA of Formula: C11H12N2O. Bye, fridends, I hope you can learn more about C11H12N2O, If you have any questions, you can browse other blog as well. See you lster.

Recently I am researching about CHIRAL SQUARAMIDE; MICHAEL ADDITION; DERIVATIVES; INHIBITORS; PYRAZOLIN-5-ONES; CONSTRUCTION; PYRAZOLONES, Saw an article supported by the National Natural Science Foundation of China (NSFC)National Natural Science Foundation of China (NSFC) [21272024]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Zhang, QD; Zhao, BL; Li, BY; Du, DM. The CAS is 86-92-0. Through research, I have a further understanding and discovery of 3-Methyl-1-p-tolyl-5-pyrazolone. COA of Formula: C11H12N2O

An enantioselective Mannich reaction between 3-fluorooxindoles and pyrazolinone ketimines has been developed for the construction of amino-pyrazolone-oxindoles containing stereogenic C-F units. Based on this new protocol that allows for the generation of two adjacent tetrasubstituted stereocenters, a variety of structurally diverse fluorinated amino-pyrazolone-oxindoles were obtained in good to excellent yields with excellent diastereoselectivities and enantioselectivities (up to 98% yield, >20 : 1 dr and >99% ee). What’s more, good yield and high stereoselectivities were obtained in the gram-scale reaction.

COA of Formula: C11H12N2O. Bye, fridends, I hope you can learn more about C11H12N2O, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

The important role of 3-Methyl-1-p-tolyl-5-pyrazolone

SDS of cas: 86-92-0. Welcome to talk about 86-92-0, If you have any questions, you can contact Zhang, QD; Zhao, BL; Li, BY; Du, DM or send Email.

Recently I am researching about CHIRAL SQUARAMIDE; MICHAEL ADDITION; DERIVATIVES; INHIBITORS; PYRAZOLIN-5-ONES; CONSTRUCTION; PYRAZOLONES, Saw an article supported by the National Natural Science Foundation of China (NSFC)National Natural Science Foundation of China (NSFC) [21272024]. Published in ROYAL SOC CHEMISTRY in CAMBRIDGE ,Authors: Zhang, QD; Zhao, BL; Li, BY; Du, DM. The CAS is 86-92-0. Through research, I have a further understanding and discovery of 3-Methyl-1-p-tolyl-5-pyrazolone. SDS of cas: 86-92-0

An enantioselective Mannich reaction between 3-fluorooxindoles and pyrazolinone ketimines has been developed for the construction of amino-pyrazolone-oxindoles containing stereogenic C-F units. Based on this new protocol that allows for the generation of two adjacent tetrasubstituted stereocenters, a variety of structurally diverse fluorinated amino-pyrazolone-oxindoles were obtained in good to excellent yields with excellent diastereoselectivities and enantioselectivities (up to 98% yield, >20 : 1 dr and >99% ee). What’s more, good yield and high stereoselectivities were obtained in the gram-scale reaction.

SDS of cas: 86-92-0. Welcome to talk about 86-92-0, If you have any questions, you can contact Zhang, QD; Zhao, BL; Li, BY; Du, DM or send Email.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

What unique challenges do researchers face in 3-Methyl-1-p-tolyl-5-pyrazolone

Quality Control of 3-Methyl-1-p-tolyl-5-pyrazolone. Welcome to talk about 86-92-0, If you have any questions, you can contact Akbari, F; Didehban, K; Farhang, M or send Email.

Quality Control of 3-Methyl-1-p-tolyl-5-pyrazolone. In 2020 EUR J PHARM SCI published article about MAGNESIUM-DL-ASPARTATE; P-TOLUIC ACID; MIXING PROPERTIES; ACTIVITY-COEFFICIENT; NRTL-SAC; 313.15 K; PREDICTION; INGREDIENTS; PARAMETERS in [Akbari, Falamarz] Eram Inst Higher Educ, Dept Chem, POB 71957-46733, Shiraz, Iran; [Didehban, Khadijeh; Farhang, Mona] Payame Noor Univ, Dept Chem, POB 19395-3697, Tehran, Iran in 2020, Cited 35. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0.

A new semi-theoretical equation is suggested for correlation of solid-liquid solubility data with temperature. The (solid + liquid) equilibrium for Terephthaldialdehyde, 4-Nitro-o-phennylenediamine, 2,4-dihydro- 5-methyl-2(4-methylphenyl)-3H-pyrazol-3-one (also named 1-(p-toly1)-3-methyl-5pyrazolone (PTMP)), 2-Amino-5-methylthiazole and 5-chloro-1-methyl-4-nitroimidazole in 18 solvents is correlated with semi-empirical models at temperatures T = 273.15 – 318.15 K under a pressure of 101.2 kPa. Moreover, a modified Apelblat model, lambda h model, Wilson model, NRTL model, new flexible equation as Akbari, Dideban and Farhang model (ADF) and for first time the modified Scatchard-Hildebrand equation were utilized to calculate the experiment values. The performance of both ADF and modified Scatchard-Hildebrand equation have been checked by calculating the solubility data with the AARD% of 1.3808% (for 775 data points) and 0.65% (for 100 data points), respectively. The Wilson model is applied to estimate the mixing Gibbs energy, mixing enthalpy, mixing entropy, activity coefficient (ln gamma(infinity)(1)) and reduced excess enthalpy (H-I(E,infinity)) at infinitesimal concentration were calculated.

Quality Control of 3-Methyl-1-p-tolyl-5-pyrazolone. Welcome to talk about 86-92-0, If you have any questions, you can contact Akbari, F; Didehban, K; Farhang, M or send Email.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Chemical Properties and Facts of 3-Methyl-1-p-tolyl-5-pyrazolone

Quality Control of 3-Methyl-1-p-tolyl-5-pyrazolone. Welcome to talk about 86-92-0, If you have any questions, you can contact Wu, GX; Xu, HH; Liu, ZR; Liu, YH; Yang, X; Zhang, XL; Huang, Y or send Email.

An article Asymmetric Organocatalysis Combined with Palladium Catalysis: Synergistic Effect on Enantioselective Mannich/alpha-Allylation Sequential Reactions of Pyrazolones in Constructing Vicinal Quaternary Stereocenters WOS:000489200100005 published article about ALLYLIC DEAROMATIZATION REACTION; STEREOCONTROLLED CONSTRUCTION; MICHAEL ADDITION; ALKYLATION; ACID; PYRAZOLIN-5-ONES; PYRAZOL-5-ONES; ALCOHOLS; BEARING in [Wu, Gengxin; Xu, Haohan; Liu, Ziran; Liu, Yonghong; Yang, Xiang; Huang, Yan] Xinjiang Univ, Coll Chem & Chem Engn, Key Lab Oil & Gas Fine Chem, Minist Educ & Xinjiang Uyghur Autonomous Reg, Urumqi 830000, Xinjiang, Peoples R China; [Zhang, Xulong] Xinjiang Uygur Autonomous Reg Prod Qual Supervis, Urumqi 830000, Xinjiang, Peoples R China in 2019, Cited 46. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0. Quality Control of 3-Methyl-1-p-tolyl-5-pyrazolone

In this letter, an efficient one-pot asymmetric sequential reaction is achieved by organo/transition metal relay catalysis in constructing two consecutive C-C bonds, which involves enantioselective amino squaramide catalytic Mannich-type addition of pyrazolones to isatin-derived ketimines and a subsequent palladium catalyzed diastereoselective allylic alkylation of pyrazolones with allylic acetates. An array of novel pyrazolone-aminooxindole-propylene structural motifs are obtained in a high level of yield and with excellent enantio- and diastereoselectivity (up to 95% yield, >20:1 dr, >99% ee). This methodology features the formation of vicinal quarternary carbon-stereocenters, and the second all-carbon tetrasubstituted stereogenic center is induced by joint action of the achiral palladium catalysis and the chiral environment generated from the Mannich step. Moreover, the usefulness of this methodology is highlighted by converting the allylic product into the carbonyl compound.

Quality Control of 3-Methyl-1-p-tolyl-5-pyrazolone. Welcome to talk about 86-92-0, If you have any questions, you can contact Wu, GX; Xu, HH; Liu, ZR; Liu, YH; Yang, X; Zhang, XL; Huang, Y or send Email.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Extracurricular laboratory: Synthetic route of 86-92-0

COA of Formula: C11H12N2O. Bye, fridends, I hope you can learn more about C11H12N2O, If you have any questions, you can browse other blog as well. See you lster.

Zhang, Y; Nie, LJ; Luo, L; Mao, JX; Liu, JX; Xu, GH; Chen, DL; Luo, HQ in [Zhang, Yong; Nie, Long-Jun; Luo, Lang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing] Garman Normal Univ, Key Lab Organopharmaceut Chem, Ganzhou 341000, Peoples R China published The selective condensation of pyrazolones to isatins in aqueous medium in 2020, Cited 69. COA of Formula: C11H12N2O. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0.

The selective condensation of pyrazolones with isatins using water as the reaction medium is presented. This strategy provides an environmentally benign synthetic route to synthesize various potentially bioactive pyrazolone substituted oxindoles. (C) 2020 Elsevier Ltd. All rights reserved.

COA of Formula: C11H12N2O. Bye, fridends, I hope you can learn more about C11H12N2O, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Archives for Chemistry Experiments of 3-Methyl-1-p-tolyl-5-pyrazolone

Bye, fridends, I hope you can learn more about C11H12N2O, If you have any questions, you can browse other blog as well. See you lster.. Recommanded Product: 3-Methyl-1-p-tolyl-5-pyrazolone

Zhang, QD; Zhao, BL; Li, BY; Du, DM in [Zhang, Qing-Da; Zhao, Bo-Liang; Li, Bing-Yu; Du, Da-Ming] Beijing Inst Technol, Sch Chem & Chem Engn, 5 South Zhongguancun St, Beijing 100081, Peoples R China published Squaramide-catalyzed asymmetric Mannich reactions between 3-fluorooxindoles and pyrazolinone ketimines in 2019, Cited 28. Recommanded Product: 3-Methyl-1-p-tolyl-5-pyrazolone. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0.

An enantioselective Mannich reaction between 3-fluorooxindoles and pyrazolinone ketimines has been developed for the construction of amino-pyrazolone-oxindoles containing stereogenic C-F units. Based on this new protocol that allows for the generation of two adjacent tetrasubstituted stereocenters, a variety of structurally diverse fluorinated amino-pyrazolone-oxindoles were obtained in good to excellent yields with excellent diastereoselectivities and enantioselectivities (up to 98% yield, >20 : 1 dr and >99% ee). What’s more, good yield and high stereoselectivities were obtained in the gram-scale reaction.

Bye, fridends, I hope you can learn more about C11H12N2O, If you have any questions, you can browse other blog as well. See you lster.. Recommanded Product: 3-Methyl-1-p-tolyl-5-pyrazolone

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Why do aromatic interactions matter of compound:3-Methyl-1-p-tolyl-5-pyrazolone

COA of Formula: C11H12N2O. About 3-Methyl-1-p-tolyl-5-pyrazolone, If you have any questions, you can contact Shaikh, I; Jadeja, RN; Patel, R or concate me.

In 2020 POLYHEDRON published article about DNA-BINDING; PLASMODIUM-FALCIPARUM; COPPER(II) COMPLEXES; CU(II) COMPLEXES; DERIVATIVES; ANTICANCER; BINARY in [Shaikh, Irfan; Jadeja, R. N.] Maharaja Sayajirao Univ Baroda, Fac Sci, Dept Chem, Vadodara 390002, India; [Patel, Rajesh] Veer Narmad South Gujarat Univ, Dept Biosci, Surat 395007, India in 2020, Cited 33. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0. COA of Formula: C11H12N2O

Three novel mixed ligand Zn(II) complexes {complex 1 = [Zn(L1)(2)(bpy)], complex 2 = [Zn(L2)(2)(bPY)], complex 3 = [Zn(L2)(2)(phen)], where bpy = 2,2′-bipyridine and phen = 1,10-phenanthroline} of 4-(4-chlorobenzoyl)-2-(3-chlorophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one (HL1) and 4-(4-chlorobenzoyl)-5-methyl-2-(p-tolyl)-2,4-dihydro-3H-pyrazol-3-one (HL2) were synthesized and characterized by H-1 and C-13 NMR, FTIR, TG-DTA, UV-Vis, elemental analysis, molar conductance and single crystal X-ray structure determination. Based on analytical and spectroscopic techniques, all the three Zn(II) complexes were found to have a distorted octahedral geometry. The ligands and the complexes were screened for antimalarial activity against plasmodium falciparum. The zinc(II) complexes showed greater antimalarial activity than their parent ligands. (C) 2020 Elsevier Ltd. All rights reserved.

COA of Formula: C11H12N2O. About 3-Methyl-1-p-tolyl-5-pyrazolone, If you have any questions, you can contact Shaikh, I; Jadeja, RN; Patel, R or concate me.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Simple exploration of 86-92-0

Welcome to talk about 86-92-0, If you have any questions, you can contact Zhang, QD; Zhao, BL; Li, BY; Du, DM or send Email.. Quality Control of 3-Methyl-1-p-tolyl-5-pyrazolone

An article Squaramide-catalyzed asymmetric Mannich reactions between 3-fluorooxindoles and pyrazolinone ketimines WOS:000477986000013 published article about CHIRAL SQUARAMIDE; MICHAEL ADDITION; DERIVATIVES; INHIBITORS; PYRAZOLIN-5-ONES; CONSTRUCTION; PYRAZOLONES in [Zhang, Qing-Da; Zhao, Bo-Liang; Li, Bing-Yu; Du, Da-Ming] Beijing Inst Technol, Sch Chem & Chem Engn, 5 South Zhongguancun St, Beijing 100081, Peoples R China in 2019, Cited 28. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0. Quality Control of 3-Methyl-1-p-tolyl-5-pyrazolone

An enantioselective Mannich reaction between 3-fluorooxindoles and pyrazolinone ketimines has been developed for the construction of amino-pyrazolone-oxindoles containing stereogenic C-F units. Based on this new protocol that allows for the generation of two adjacent tetrasubstituted stereocenters, a variety of structurally diverse fluorinated amino-pyrazolone-oxindoles were obtained in good to excellent yields with excellent diastereoselectivities and enantioselectivities (up to 98% yield, >20 : 1 dr and >99% ee). What’s more, good yield and high stereoselectivities were obtained in the gram-scale reaction.

Welcome to talk about 86-92-0, If you have any questions, you can contact Zhang, QD; Zhao, BL; Li, BY; Du, DM or send Email.. Quality Control of 3-Methyl-1-p-tolyl-5-pyrazolone

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics