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An article The selective condensation of pyrazolones to isatins in aqueous medium WOS:000515447100005 published article about HENRY NITROALDOL REACTIONS; ORGANIC-SYNTHESIS; ON-WATER; DERIVATIVES; ANTIPYRINE; ALCOHOLS; HETEROCYCLES; CHEMISTRY; CYCLIZATION; EFFICIENT in [Zhang, Yong; Nie, Long-Jun; Luo, Lang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing] Garman Normal Univ, Key Lab Organopharmaceut Chem, Ganzhou 341000, Peoples R China in 2020, Cited 69. Computed Properties of C11H12N2O. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0

The selective condensation of pyrazolones with isatins using water as the reaction medium is presented. This strategy provides an environmentally benign synthetic route to synthesize various potentially bioactive pyrazolone substituted oxindoles. (C) 2020 Elsevier Ltd. All rights reserved.

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Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
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Recommanded Product: 86-92-0. Welcome to talk about 86-92-0, If you have any questions, you can contact Zhang, Y; Nie, LJ; Luo, L; Mao, JX; Liu, JX; Xu, GH; Chen, DL; Luo, HQ or send Email.

I found the field of Chemistry very interesting. Saw the article The selective condensation of pyrazolones to isatins in aqueous medium published in 2020. Recommanded Product: 86-92-0, Reprint Addresses Zhang, Y; Luo, HQ (corresponding author), Garman Normal Univ, Key Lab Organopharmaceut Chem, Ganzhou 341000, Peoples R China.. The CAS is 86-92-0. Through research, I have a further understanding and discovery of 3-Methyl-1-p-tolyl-5-pyrazolone

The selective condensation of pyrazolones with isatins using water as the reaction medium is presented. This strategy provides an environmentally benign synthetic route to synthesize various potentially bioactive pyrazolone substituted oxindoles. (C) 2020 Elsevier Ltd. All rights reserved.

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Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

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Welcome to talk about 86-92-0, If you have any questions, you can contact Ibrahim, HM; Behbehani, H or send Email.. Application In Synthesis of 3-Methyl-1-p-tolyl-5-pyrazolone

Authors Ibrahim, HM; Behbehani, H in AMER CHEMICAL SOC published article about C-H; BIOLOGICAL EVALUATION; PHOTOREDOX CATALYSIS; IN-VITRO; ALPHA-GLUCOSIDASE; PYRAZOLE; DERIVATIVES; POTENT; INHIBITORS; DESIGN in [Ibrahim, Hamada Mohamed; Behbehani, Haider] Kuwait Univ, Fac Sci, Chem Dept, POB 5969, Safat 13060, Kuwait; [Ibrahim, Hamada Mohamed] Fayoum Univ, Fac Sci, Chem Dept, POB 63514, Al Fayyum, Egypt in 2019, Cited 99. Application In Synthesis of 3-Methyl-1-p-tolyl-5-pyrazolone. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0

A novel, metal catalyst-free, and efficient method has been developed for the synthesis of (pyrazol-4-ylidene) pyridine derivatives. The process involves dehydrogenative coupling of 1-amino-2-imino-pyridines with 1-aryl-5pyrazolone derivatives utilizing O-2 as the sole oxidant. The new method benefits from a high atom economy, efficiency, and substrate scope, as well as the simplicity of reaction and product purification procedures.

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Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

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Welcome to talk about 86-92-0, If you have any questions, you can contact Zhang, QD; Zhao, BL; Li, BY; Du, DM or send Email.. Computed Properties of C11H12N2O

Computed Properties of C11H12N2O. In 2019 ORG BIOMOL CHEM published article about CHIRAL SQUARAMIDE; MICHAEL ADDITION; DERIVATIVES; INHIBITORS; PYRAZOLIN-5-ONES; CONSTRUCTION; PYRAZOLONES in [Zhang, Qing-Da; Zhao, Bo-Liang; Li, Bing-Yu; Du, Da-Ming] Beijing Inst Technol, Sch Chem & Chem Engn, 5 South Zhongguancun St, Beijing 100081, Peoples R China in 2019, Cited 28. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0.

An enantioselective Mannich reaction between 3-fluorooxindoles and pyrazolinone ketimines has been developed for the construction of amino-pyrazolone-oxindoles containing stereogenic C-F units. Based on this new protocol that allows for the generation of two adjacent tetrasubstituted stereocenters, a variety of structurally diverse fluorinated amino-pyrazolone-oxindoles were obtained in good to excellent yields with excellent diastereoselectivities and enantioselectivities (up to 98% yield, >20 : 1 dr and >99% ee). What’s more, good yield and high stereoselectivities were obtained in the gram-scale reaction.

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Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

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An article Pd(ii)-Catalyzed alkyne annulation through allylic isomerization: synthesis of spiro-cyclopentadiene pyrazolones WOS:000653779300001 published article about PHOTOPHYSICAL PROPERTIES; ACTIVATION; FUNCTIONALIZATION; MECHANISM in [Changmai, Sumi; Sultana, Sabera; Gogoi, Sanjib] North East Inst Sci & Technol, CSIR, Chem Sci & Technol Div, Appl Organ Chem, Jorhat 785006, Assam, India; [Changmai, Sumi; Sultana, Sabera; Gogoi, Sanjib] AcSIR, Ghaziabad 201002, India; [Sarma, Bipul] Tezpur Univ, Dept Chem Sci, Tezpur 784028, Assam, India in 2021, Cited 30. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0. Application In Synthesis of 3-Methyl-1-p-tolyl-5-pyrazolone

The Pd(ii)-catalyzed activation of Csp(2)-H bond and double alkyne annulation which proceeds via allylic isomerization is reported for the first time. This reaction of antipyrines with alkynes provides an efficient synthetic route for the biologically important spiro-cyclopentadiene pyrazolones. In the presence of Lawesson’s reagent, this Pd(ii)-catalyzed annulation reaction affords another spiro-cyclopentadiene pyrazolone which displays very good fluorescence properties.

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Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

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Recently I am researching about C-H; BIOLOGICAL EVALUATION; PHOTOREDOX CATALYSIS; IN-VITRO; ALPHA-GLUCOSIDASE; PYRAZOLE; DERIVATIVES; POTENT; INHIBITORS; DESIGN, Saw an article supported by the Kuwait University [SC13/18]; [GS01/01]; [GS01/05]; [GS01/03]; [GS03/08]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Ibrahim, HM; Behbehani, H. The CAS is 86-92-0. Through research, I have a further understanding and discovery of 3-Methyl-1-p-tolyl-5-pyrazolone. Quality Control of 3-Methyl-1-p-tolyl-5-pyrazolone

A novel, metal catalyst-free, and efficient method has been developed for the synthesis of (pyrazol-4-ylidene) pyridine derivatives. The process involves dehydrogenative coupling of 1-amino-2-imino-pyridines with 1-aryl-5pyrazolone derivatives utilizing O-2 as the sole oxidant. The new method benefits from a high atom economy, efficiency, and substrate scope, as well as the simplicity of reaction and product purification procedures.

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Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

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Quality Control of 3-Methyl-1-p-tolyl-5-pyrazolone. Welcome to talk about 86-92-0, If you have any questions, you can contact Changmai, S; Sultana, S; Sarma, B; Gogoi, S or send Email.

Quality Control of 3-Methyl-1-p-tolyl-5-pyrazolone. In 2021 CHEM COMMUN published article about PHOTOPHYSICAL PROPERTIES; ACTIVATION; FUNCTIONALIZATION; MECHANISM in [Changmai, Sumi; Sultana, Sabera; Gogoi, Sanjib] North East Inst Sci & Technol, CSIR, Chem Sci & Technol Div, Appl Organ Chem, Jorhat 785006, Assam, India; [Changmai, Sumi; Sultana, Sabera; Gogoi, Sanjib] AcSIR, Ghaziabad 201002, India; [Sarma, Bipul] Tezpur Univ, Dept Chem Sci, Tezpur 784028, Assam, India in 2021, Cited 30. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0.

The Pd(ii)-catalyzed activation of Csp(2)-H bond and double alkyne annulation which proceeds via allylic isomerization is reported for the first time. This reaction of antipyrines with alkynes provides an efficient synthetic route for the biologically important spiro-cyclopentadiene pyrazolones. In the presence of Lawesson’s reagent, this Pd(ii)-catalyzed annulation reaction affords another spiro-cyclopentadiene pyrazolone which displays very good fluorescence properties.

Quality Control of 3-Methyl-1-p-tolyl-5-pyrazolone. Welcome to talk about 86-92-0, If you have any questions, you can contact Changmai, S; Sultana, S; Sarma, B; Gogoi, S or send Email.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

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Quality Control of 3-Methyl-1-p-tolyl-5-pyrazolone. Welcome to talk about 86-92-0, If you have any questions, you can contact Lu, H; Zhang, HX; Tan, CY; Liu, JY; Wei, H; Xu, PF or send Email.

Quality Control of 3-Methyl-1-p-tolyl-5-pyrazolone. Recently I am researching about N-HETEROCYCLIC CARBENE; ENANTIOSELECTIVE CONSTRUCTION; ORGANOCATALYSIS; PYRAZOLONES; ANNULATION; SCAFFOLDS; OXINDOLES; CATALYSIS, Saw an article supported by the NSFCNational Natural Science Foundation of China (NSFC) [21632003, 21871116, 21572087]; key program of Gansu province [17ZD2GC011]; 111 program from the MOE of P. R. China. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Lu, H; Zhang, HX; Tan, CY; Liu, JY; Wei, H; Xu, PF. The CAS is 86-92-0. Through research, I have a further understanding and discovery of 3-Methyl-1-p-tolyl-5-pyrazolone

A sequential and general strategy has been successfully developed for the synthesis of spiropyrazolone scaffolds. This intriguing transformation of the asymmetric multicomponent catalysis process was realized with the combination of Michael addition/chlorination/nucleophilic substitution in a one-pot sequence, giving rise to a series of spiropyrazolones with fully substituted cyclopropanes and spiro-dihydrobenzofurans containing continuous stereogenic centers in good yields with excellent stereoselectivities.

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Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

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An article One-Pot Asymmetric Synthesis of Spiropyrazolone-Linked Cyclopropanes and Benzofurans through a General Michael Addition/Chlorination/Nucleophilic Substitution Sequence WOS:000481979200038 published article about N-HETEROCYCLIC CARBENE; ENANTIOSELECTIVE CONSTRUCTION; ORGANOCATALYSIS; PYRAZOLONES; ANNULATION; SCAFFOLDS; OXINDOLES; CATALYSIS in [Lu, Hong; Zhang, Huan-Xin; Tan, Chang-Yin; Liu, Jin-Yu; Xu, Peng-Fei] Lanzhou Univ, Sch Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Gansu, Peoples R China; [Lu, Hong; Wei, Hao] Northwest Univ, Coll Chem & Mat Sci, Natl Demonstrat Ctr Expt Chem Educ, Key Lab Synthet & Nat Funct Mol Chem,Minist Educ, Xian 710127, Shaanxi, Peoples R China in 2019, Cited 45. SDS of cas: 86-92-0. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0

A sequential and general strategy has been successfully developed for the synthesis of spiropyrazolone scaffolds. This intriguing transformation of the asymmetric multicomponent catalysis process was realized with the combination of Michael addition/chlorination/nucleophilic substitution in a one-pot sequence, giving rise to a series of spiropyrazolones with fully substituted cyclopropanes and spiro-dihydrobenzofurans containing continuous stereogenic centers in good yields with excellent stereoselectivities.

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Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

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SDS of cas: 86-92-0. Welcome to talk about 86-92-0, If you have any questions, you can contact Wu, GX; Xu, HH; Liu, ZR; Liu, YH; Yang, X; Zhang, XL; Huang, Y or send Email.

SDS of cas: 86-92-0. Recently I am researching about ALLYLIC DEAROMATIZATION REACTION; STEREOCONTROLLED CONSTRUCTION; MICHAEL ADDITION; ALKYLATION; ACID; PYRAZOLIN-5-ONES; PYRAZOL-5-ONES; ALCOHOLS; BEARING, Saw an article supported by the National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [21462042, 21262036]. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Wu, GX; Xu, HH; Liu, ZR; Liu, YH; Yang, X; Zhang, XL; Huang, Y. The CAS is 86-92-0. Through research, I have a further understanding and discovery of 3-Methyl-1-p-tolyl-5-pyrazolone

In this letter, an efficient one-pot asymmetric sequential reaction is achieved by organo/transition metal relay catalysis in constructing two consecutive C-C bonds, which involves enantioselective amino squaramide catalytic Mannich-type addition of pyrazolones to isatin-derived ketimines and a subsequent palladium catalyzed diastereoselective allylic alkylation of pyrazolones with allylic acetates. An array of novel pyrazolone-aminooxindole-propylene structural motifs are obtained in a high level of yield and with excellent enantio- and diastereoselectivity (up to 95% yield, >20:1 dr, >99% ee). This methodology features the formation of vicinal quarternary carbon-stereocenters, and the second all-carbon tetrasubstituted stereogenic center is induced by joint action of the achiral palladium catalysis and the chiral environment generated from the Mannich step. Moreover, the usefulness of this methodology is highlighted by converting the allylic product into the carbonyl compound.

SDS of cas: 86-92-0. Welcome to talk about 86-92-0, If you have any questions, you can contact Wu, GX; Xu, HH; Liu, ZR; Liu, YH; Yang, X; Zhang, XL; Huang, Y or send Email.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics