Category: 67-51-6

Recently I am researching about POLYHALOGENATED NITROBUTADIENES; CHEMISTRY, Saw an article supported by the Belarusian Republican Foundation for Basic Research [X18M-023]. Published in MAIK NAUKA/INTERPERIODICA/SPRINGER in NEW YORK ,Authors: Kolesnyk, IA; Petkevich, SK; Tsaryk, AD; Kurman, PV; Potkin, VI. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole. Recommanded Product: 67-51-6

The reaction of 3,4,4-trichloro-1,1-bis(3,5-dimethyl-1H-pyrazol-1-yl)-2-nitrobuta-1,3-diene with 2-aminopyridine gave a polysubstituted pyrido[1,2-a]pyrimidine derivative with an aminopyridine residue in the 2-position, whereas heterocyclization of 3,4,4-trichloro-1,1-bis(1H-benzotriazol-1-yl)-2-nitrobuta-1,3-diene with substituted 2-aminopyridines afforded 2-(1H-berrzotriazol-1-yl)pyrido[1,2-a]pyrimidines. 2-(Morpholin-4-yl), 2-amino, and 2-(2-hydroxyethylamino) derivatives of polysubstituted pyrido[1,2-a]pyrimidines were synthesized, and those containing a 2-hydroxyethylamino group were converted to the corresponding 4,5-dichloro-1,2-thiazole-1-carboxylates. Specific features of heterocyclizations of benzotriazolyl and dimethylpyrazolyl derivatives of trichloronitro-1,3-butadiene to pyrimidine and pyrazole systems were revealed.

Recommanded Product: 67-51-6. Welcome to talk about 67-51-6, If you have any questions, you can contact Kolesnyk, IA; Petkevich, SK; Tsaryk, AD; Kurman, PV; Potkin, VI or send Email.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Recommanded Product: 3,5-Dimethyl-1H-pyrazole. I found the field of Chemistry; Science & Technology – Other Topics; Engineering very interesting. Saw the article Performance of Base and Noble Metals for Electrocatalytic Hydrogenation of Bio-Oil-Derived Oxygenated Compounds published in 2020.0, Reprint Addresses Gutierrez, OY; Holladay, JD (corresponding author), Pacific Northwest Natl Lab, Inst Integrated Catalysis, Energy & Environm Directorate, Richland, WA 99352 USA.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole.

Electrocatalytic hydrogenation is a particularly attractive approach for converting the most unstable compounds in biogenic feedstocks at ambient conditions without external H-2. Here, we synthesized a variety of carbon-supported transition metal catalysts and characterized their activity for the electrocatalytic hydrogenation of a series of model compounds and pyrolysis bio-oil. Carbonyl compounds, especially aromatic aldehydes, such as furfural and benzaldehyde, are particularly inclined to hydrogenation driven by an applied current. This was verified with pure solutions of the model compounds and with pyrolysis bio-oil, where we achieved stable and steady continuous operation on Pd. When optimal catalyst composition was chosen, the conversion of benzaldehyde shifted from alcohol production (e.g., on Pd and Cu) to dimerization (e.g., on Co, Ni, and Zn). Pd and Cu were shown to offer the best compromise between reaction rates and efficiency although, in general, base metals offer similar conversions but better efficiencies than noble metals. Thus, the present work offers foundational results and guidelines for choosing the optimal metal catalyst and the applied potential for processing organic feedstocks as a function of its composition.

Recommanded Product: 3,5-Dimethyl-1H-pyrazole. Welcome to talk about 67-51-6, If you have any questions, you can contact Andrews, E; Lopez-Ruiz, JA; Egbert, JD; Koh, K; Sanyal, U; Song, M; Li, DS; Karkamkar, AJ; Derewinski, MA; Holladay, J; Gutierrez, OY; Holladay, JD or send Email.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

An article Synthesis of Polysubstituted Pyridopyrimidines, Pyrimidines, and Pyrazoles Based on 1,1-Bis(1H-benzotriazol-1-yl)-and 1,1-Bis(3,5-dimethyl-1H-pyrazol-1-yl)-3,4,4-trichloro-2-nitrobuta-1,3-dienes WOS:000520467600004 published article about POLYHALOGENATED NITROBUTADIENES; CHEMISTRY in [Kolesnyk, I. A.; Petkevich, S. K.; Tsaryk, A. D.; Potkin, V. I.] Natl Acad Sci Belarus, Inst Phys Organ Chem, Minsk 220072, BELARUS; [Kurman, P. V.] Natl Acad Sci Belarus, Inst Bioorgan Chem, Minsk 220141, BELARUS in 2020.0, Cited 16.0. Quality Control of 3,5-Dimethyl-1H-pyrazole. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6

The reaction of 3,4,4-trichloro-1,1-bis(3,5-dimethyl-1H-pyrazol-1-yl)-2-nitrobuta-1,3-diene with 2-aminopyridine gave a polysubstituted pyrido[1,2-a]pyrimidine derivative with an aminopyridine residue in the 2-position, whereas heterocyclization of 3,4,4-trichloro-1,1-bis(1H-benzotriazol-1-yl)-2-nitrobuta-1,3-diene with substituted 2-aminopyridines afforded 2-(1H-berrzotriazol-1-yl)pyrido[1,2-a]pyrimidines. 2-(Morpholin-4-yl), 2-amino, and 2-(2-hydroxyethylamino) derivatives of polysubstituted pyrido[1,2-a]pyrimidines were synthesized, and those containing a 2-hydroxyethylamino group were converted to the corresponding 4,5-dichloro-1,2-thiazole-1-carboxylates. Specific features of heterocyclizations of benzotriazolyl and dimethylpyrazolyl derivatives of trichloronitro-1,3-butadiene to pyrimidine and pyrazole systems were revealed.

Welcome to talk about 67-51-6, If you have any questions, you can contact Kolesnyk, IA; Petkevich, SK; Tsaryk, AD; Kurman, PV; Potkin, VI or send Email.. Quality Control of 3,5-Dimethyl-1H-pyrazole

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

An article Space Craft-like Octanuclear Co(II)-Silsesquioxane Nanocages: Synthesis, Structure, Magnetic Properties, Solution Behavior, and Catalytic Activity for Hydroboration of Ketones WOS:000463462200062 published article about COORDINATION POLYMERS; SELECTIVE HYDROBORATION; MASS-SPECTROMETRY; METAL; ALDEHYDES; COMPLEXES; CARBONYL; COBALT; CLUSTERS; HYDROGENATION in [Liu, Ya-Nan; Wang, Wen-Guang; Tung, Chen-Ho; Sun, Di] Shandong Univ, State Key Lab Crystal Mat, Sch Chem & Chem Engn, Key Lab Colloid & Interface Chem,Minist Educ, Jinan 250100, Peoples R China; [Li, Yun-Wu; Sun, Di] Liaocheng Univ, Shandong Prov Key Lab Chem Energy Storage & Novel, Liaocheng 252000, Shandong, Peoples R China; [Li, Yun-Wu; Sun, Di] Liaocheng Univ, Sch Chem & Chem Engn, Liaocheng 252000, Shandong, Peoples R China; [Su, Hai-Feng] Xiamen Univ, Coll Chem & Chem Engn, State Key Lab Phys Chem Solid Surfaces, Xiamen 361005, Peoples R China; [Su, Hai-Feng] Xiamen Univ, Coll Chem & Chem Engn, Dept Chem, Xiamen 361005, Peoples R China; [Jaglicic, Zvonko] Univ Ljubljana, Fac Civil & Geodet Engn, Jamova 2, Ljubljana 1000, Slovenia; [Jaglicic, Zvonko] Univ Ljubljana, Inst Math Phys & Mech, Jamova 2, Ljubljana 1000, Slovenia; [Liu, Qing-Yun] Shandong Univ Sci & Technol, Coll Chem & Environm Engn, Qingdao 266590, Shandong, Peoples R China in 2019.0, Cited 97.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. Product Details of 67-51-6

Two novel space craft-like octanuclear Co(II)-silsesquioxane nanocages, {Co-8[(MeSiO2)(4)](2)(dmpz)(8)} (SD/Co8a) and {Co-8[(PhSiO2)(4)](2)(dmpz)(8)} (SD/Co8b) (SD = SunDi; Hdmpz = 3,5-dimethylpyrazole), have been constructed from two similar multidentate silsesquioxane ligands assisted with a pyrazole ligand. The Cob skeleton consists of eight tetrahedral Co(II) ions arranged in a ring and is further capped by two (MeSiO2)(4) ligands up and down. The auxiliary dmpz(-) ligands seal the ring finally. Electrospray ionization mass spectrometry revealed SD/Co8a and SD/Co8b are highly stable in CH2Cl2. Magnetic analysis implies that SD/Co8a announces antiferromagnetic interactions between Co(II) ions. Moreover, both of them display good homogeneous catalytic activity for hydroboration of ketones in the presence of pinacolborane under mild conditions.

Welcome to talk about 67-51-6, If you have any questions, you can contact Liu, YN; Su, HF; Li, YW; Liu, QY; Jaglicic, Z; Wang, WG; Tung, CH; Sun, D or send Email.. Product Details of 67-51-6

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Quality Control of 3,5-Dimethyl-1H-pyrazole. In 2020.0 J AM CHEM SOC published article about ARYL FLUORIDES; BOND FORMATION; AMINATION; ACTIVATION in [Pistritto, Vincent A.; Schutzbach-Horton, Megan E.; Nicewicz, David A.] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA in 2020.0, Cited 41.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.

Nucleophilic aromatic substitution (SNAr) is a classical reaction with well-known reactivity toward electron-poor fluoroarenes. However, electron-neutral and electron-rich fluoro(hetero)arenes are considerably underrepresented. Herein, we present a method for the nucleophilic defluorination of unactivated fluoroarenes enabled by cation radical-accelerated nucleophilic aromatic substitution. The use of organic photoredox catalysis renders this method operationally simple under mild conditions and is amenable to various nucleophile classes, including azoles, amines, and carboxylic acids. Select fluorinated heterocycles can be functionalized using this method. In addition, the late-stage functionalization of pharmaceuticals is also presented. Computational studies demonstrate that the site selectivity of the reaction is dictated by arene electronics.

Quality Control of 3,5-Dimethyl-1H-pyrazole. Bye, fridends, I hope you can learn more about C5H8N2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

An article Correlation between Equilibrium Constant and Stabilization Energy: A Combined Approach Based on Chemical Thermodynamics, Statistical Thermodynamics, and Density Functional Reactivity Theory WOS:000515216300008 published article about DFRT BASED APPROACH; BASIS-SET; NUCLEOBASES; UNDERSTAND; CLUSTERS; HARDNESS; BINDING; ADDUCT in [Hamid, Aabid; Roy, Ram Kinkar] Birla Inst Technol & Sci, Dept Chem, Pilani 333031, Rajasthan, India in 2020.0, Cited 28.0. Formula: C5H8N2. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6

In the present work, an attempt is made to establish the correlation between equilibrium constant and stabilization energy [Delta E-SE(AB)] generated from density functional reactivity theory (DFRT). The reactions chosen here are of type A + B (sic) AB (i.e., adduct formation type) between an electron acceptor, A, and an electron donor, B. The representative acceptors are methyltrioxorhenium (MTO) and substituted benzaldehydes whereas donors are 26 mono- and bidentate ligands (having N-donors) and semicarbazide. The trends of experimentally generated equilibrium constant (K) values match with those of Delta E-SE(AB) in most of the cases, both in gas phase as well as in solvent. Justification of this reliable correlation is provided analytically using the expressions of standard Gibbs free energy of reaction (i.e., Delta(r)G(theta)) and the stabilization energy expression generated by DFRT. A further analytical explanation (albeit not very rigorous) is provided through statistical thermodynamics showing how equilibrium constant (K) is related to Delta E-SE(AB) for reactions of the type A + B (sic) AB, where either A or B is a common species.

Formula: C5H8N2. Bye, fridends, I hope you can learn more about C5H8N2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Gogoi, A; Dutta, D; Verma, AK; Nath, H; Frontera, A; Guha, AK; Bhattacharyya, MK in [Gogoi, Anshuman; Dutta, Debajit; Nath, Hiren; Guha, Ankur K.; Bhattacharyya, Manjit K.] Cotton Univ, Dept Chem, Gauhati 781001, Assam, India; [Verma, Akalesh K.] Cotton Univ, Dept Zool, Cell & Biochem Technol Lab, Gauhati 781001, Assam, India; [Frontera, Antonio] Univ Illes Balears, Dept Quim, Crta Valldemossa Km 7-7, Palma De Mallorca 07122, Baleares, Spain published Energetically favorable anti-electrostatic hydrogen bonded cationic clusters in Ni(II) 3,5-dimethylpyrazole complexes: Anticancer evaluation and theoretical studies in 2019.0, Cited 94.0. Product Details of 67-51-6. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.

Two new Ni(II) coordination complexes of pyrazole and acetato ligands, involving nitrate and chloride counter anions, viz. [Ni(Hdmpz)(2)(CH3COO)(H2O)(3)]NO3 center dot 2H(2)O (1) and [Ni(Hdmpz)(2)(CH3COO)(H2O)(3)]Cl (2) (where Hdmpz = 3,5-dimethylpyrazole), have been synthesized in purely aqueous medium at room temperature. The complexes have been characterized by elemental analysis, FT-IR, electronic spectroscopy, PXRD, TGA and single crystal X-ray diffraction. The H-bonds established between the isostructural cationic [Ni(Hdmpz)(2)(CH3COO)(H2O)(3)](+) moieties of both complexes can be classified as anti-electrostatic H-bonds (AEHBs) and these have been studied using DFT calculations. Remarkably, in one case these AEHBs exhibit favorable interaction energies, thus indicating that the attractive nature of the H-bonds is able to compensate the pure electrostatic repulsion. The analyses of the cell viability results for the DL cell line show a significant concentration dependent decrease by compounds 1 and 2 with a negligible cytotoxic effect observed against normal cells (PBMC) in comparison to the cancer cells (DL). The cytotoxic activity of these compounds in DL cells occurs via apoptosis. Molecular docking and SAR analysis reveal that the compounds possess high binding affinities against most common cancer target proteins. (C) 2019 Elsevier Ltd. All rights reserved.

Product Details of 67-51-6. Welcome to talk about 67-51-6, If you have any questions, you can contact Gogoi, A; Dutta, D; Verma, AK; Nath, H; Frontera, A; Guha, AK; Bhattacharyya, MK or send Email.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Recommanded Product: 3,5-Dimethyl-1H-pyrazole. In 2020.0 ACTA CRYSTALLOGR E published article about COMPLEXES; CU(II); WELL in [Vynohradov, Oleksandr S.; Pavlenko, Vadim A.; Naumova, Dina D.; Partsevska, Sofiia, V] Taras Shevchenko Natl Univ Kyiv, Dept Chem, Volodymyrska Str 64-13, UA-01601 Kiev, Ukraine; [Shova, Sergiu] Poni Petru Inst Macromol Chem, Voda 41A, Iasi 700487, Romania; [Safarmamadov, Safarmamad M.] Tajik Natl Univ, Dept Chem, 17 Rudaki Ave, Dushanbe 734025, Tajikistan in 2020.0, Cited 22.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.

In the title bicyclic trinuclear pyrazolate aminoalcohol complex, [Cu-3(C5H7N2)(2)-(C6H14NO3)(2)]Br-2 center dot 1.5H(2)O, the central Cu atom lies on a center of symmetry and is involved in the formation of two five-membered rings. It has a coordination number of 4, is in a distorted tetrahedral environment and is connected by the bridging oxygen atoms of the deprotonated OH groups of different aminoalcohol groups, and by the N atoms of deprotonated dimethylpyrazole ligands. The peripheral Cu atom is in a trigonal-bipyramidal coordination environment formed by the nitrogen atom of the deprotonated bridging dimethylpyrazole unit, the bridging oxygen atom of the deprotonated OH group, two oxygen atoms of the protonated hydroxy groups and the nitrogen atom of triethanolamine. One of the C atoms and the Br- anion were found to be disordered over two positions with occupancy factors of 0.808 (9):0.192 (9) and 0.922 (3):0.078 (3), respectively.

Welcome to talk about 67-51-6, If you have any questions, you can contact Vynohradov, OS; Pavlenko, VA; Naumova, DD; Partsevska, SV; Shova, S; Safarmamadov, SM or send Email.. Recommanded Product: 3,5-Dimethyl-1H-pyrazole

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

An article Nickel(II) complexes with tripodal NNN ligands as homogenous and supported catalysts for ethylene oligomerization WOS:000456751700004 published article about BRANCHED POLYETHYLENE; FUNCTIONALIZED POLYOLEFINS; ALKYLALUMINUM COCATALYST; METAL-COMPLEXES; NITROGEN DONOR; AMINE LIGANDS; POLYMERIZATION; ALUMINUM; NMR; TEMPERATURE in [Tuskaev, Vladislav A.; Zubkevich, Sergei V.; Gagieva, Svetlana Ch.; Bulychev, Boris M.] Moscow MV Lomonosov State Univ, Chem Dept, Leninskie Gory 11, Moscow 119991, Russia; [Tuskaev, Vladislav A.; Kononova, Elena G.; Khrustalev, Victor N.; Zarubin, Dmitry N.] Russian Acad Sci, AN Nesmeyanov Inst Organoelement Cpds, Vavilov Str 28, Moscow 119991, Russia; [Saracheno, Daniele] Dimitri Mendeleev Univ Chem Technol Russia, Higher Coll Chem Russia, Miusskaya Sq 9, Moscow 125047, Russia; [Dorovatovskii, Pavel V.; Khrustalev, Victor N.] Natl Res Ctr, Kurchatov Inst, Moscow, Russia; [Khrustalev, Victor N.] Peoples Friendship Univ Russia RUDN, Moscow, Russia; [Kissin, Yury V.] Rutgers State Univ, Dept Chem & Chem Biol, 123 Bevier Rd, Piscataway, NJ 08854 USA in 2019.0, Cited 73.0. Recommanded Product: 67-51-6. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6

Four new coordination compounds of nickel (II) with derivatives of N,N-bis(pyrazol-1-ylmethyl)propylamine were synthesized; their composition and structure were confirmed with IR-spectroscopy and elemental analysis. The structures of products 13 and 15 were unambiguously established in an X-ray diffraction study. Compounds 13 and 15 crystallize in the orthorhombic space groups Pna2(1) and P2(1)2(1)2(1) correspondingly and represent a monomeric octahedral nickel complexes, that are typical for tridentate scorpion-type ligands. New method for immobilization of nickel complexes with derivatives of N,N-bis(pyrazol-1-ylmethyl)propylamine on silica gel modified with aminopropyl groups was proposed. The EXAFS/XANES analysis indicated that Ni atom in the supported complexes adopt almost octahedral geometry, being partly surrounded by nitrogen atoms from organic ligand and partly grafted to silica surface through silanol groups, with Br- in outer coordination sphere. Both the original and the supported complexes, when activated with Et2AlCl or Et3Al2Cl3, catalyze ethylene oligomerization with the predominant formation of butene isomers. Generally, the immobilized complexes show higher activity and better selectivity towards 1-butene formation.

Recommanded Product: 67-51-6. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Tuskaev, VA; Zubkevich, SV; Saracheno, D; Gagieva, SC; Dorovatovskii, PV; Kononova, EG; Khrustalev, VN; Zarubin, DN; Bulychev, BM; Kissin, YV or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

An article Energetically significant unconventional pi-pi contacts involving fumarate in a novel coordination polymer of Zn(II): In-vitro anticancer evaluation and theoretical studies WOS:000471754200001 published article about METAL-ORGANIC FRAMEWORKS; CRYSTAL-STRUCTURE; SUPRAMOLECULAR ASSOCIATION; STRUCTURAL-CHARACTERIZATION; LIGANDS SYNTHESIS; HOLE INTERACTION; ZINC-COMPLEXES; DNA-BINDING; PYRAZOLE; CU(II) in [Gogoi, Anshuman; Das, Amal; Bhattacharyya, Manjit K.] Cotton Univ, Dept Chem, Gauhati 781001, Assam, India; [Frontera, Antonio] Univ Illes Balears, Dept Quim, Crta Valldemossa Km 7-7, Palma De Mallorca 07122, Baleares, Spain; [Verma, Akalesh K.] Cotton Univ, Dept Zool, Cell & Biochem Technol Lab, Gauhati 781001, Assam, India in 2019.0, Cited 96.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. HPLC of Formula: C5H8N2

A new fumarato bridged Zn(II) coordination polymer viz. catena[mu-fumaratobis(3,5-dimethylpyrazole)zinc(II) trihydrate],{[Zn-2(mu-fum)(2)(Hdmpz)(4)]center dot 3H(2)O}(n) (1) (where, fum = fumarate, Hdmpz = 3,5-dimethylpyrazole) has been synthesized in purely aqueous medium at room temperature. The compound is structurally characterized by single crystal X-ray diffraction, FT-IR, electronic spectroscopy, PXRD and TGA. The zig-zag polymeric chain of 1 self assembles into a 2D supramolecular network via C-H center dot center dot center dot pi, C-H center dot center dot center dot C, N-H-center dot center dot center dot O and C-H center dot center dot center dot O interactions. Particularly relevant in 1, since in addition to the aforementioned non-covalent interactions, the electron rich pi-system of fumarate is involved in energetically significant unconventional pi-pi contacts with the electron poor pi-cloud of Hdmpz, which have been analyzed by DFT calculations and characterized using the non-covalent interaction (NCI) plot index. The strong H-bond agrees well with the MEP analysis since it is established between the H-bond donor involving NH group of Hdmpz and the H-bond acceptor involving O-atom of carboxylate moiety. The compound has been investigated for anticancer activities considering cell cytotoxicity, apoptosis and molecular docking as parameters in Dalton’s lymphoma (DL) malignant cancer cell line and results were compared with cisplatin (reference drug) under the same experimental conditions. Interestingly, negligible cytotoxic effect was observed against normal cells (PBMC) in comparison to the cancer cells (DL). The treatment of the compound caused appearance of apoptotic cells as evident by fluorescence based nuclear morphology study. The in silica study reveals that the compound interacts with the antiapoptotic proteins such as bcl-2, bcl-XL and Mcl-1 which may lead to apoptotic cell death.

HPLC of Formula: C5H8N2. Welcome to talk about 67-51-6, If you have any questions, you can contact Gogoi, A; Das, A; Frontera, A; Verma, AK; Bhattacharyya, MK or send Email.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics