Category: 67-51-6

Product Details of 67-51-6. I found the field of Chemistry very interesting. Saw the article Modular Design Strategy toward Second-Generation Tridentate Carbodiphosphorane N,C,N Ligands with a Central Four-Electron Carbon Donor Motif and Their Complexes published in 2021.0, Reprint Addresses Sundermeyer, J (corresponding author), Philipps Univ Marburg, Fachbereich Chem & Wissensch, Zentrum Mat, D-35043 Marburg, Germany.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole.

The reaction of sym-bis(P-chlorodiphenyl)-carbodiphosphorane (1) with difunctional nucleophiles leads to carbodiphosphoranes carrying two additional chelating N-donor functionalities. A proof of concept is demonstrated by the synthesis and characterization of sym-bis(3,5-dimethyl-1H-pyrazol-1-yl)-carbodiphosphorane (CDP((3,5-Me)Pz)(2), 2) and sym-bis(pyridin-2-yloxy)carbodiphosphorane (CDP(O-Py-2)(2), 3). Due to their superbasic central two-/four-electron carbon donor functionality, these neutral ligands are electronically flexible to act as neutral six-or eight-electron donors, as pincer ligand templates, or as two geminally metal bridging ligands. Their potential to form monoand dinuclear complexes involving two 6-ring or two 5-ring N,C-chelate ring motives has been explored. Complexes of 2 and 3 with fac-[M(CO)(3)] fragments (ls d(6); M = Cr, Mo, W) were used as spectroscopic probes. They reveal a strong sigma-donor and potential pi-donor ability of the central carbon donor pushing electron density for enhanced M-CO back-bonding into the metal d orbitals. DFT calculations consolidate this observation. Dinuclear and multinuclear d(10) Cu(I) complexes have been formed and structurally investigated upon treating these CDP ligands 2 and 3 with CuX (X = Cl, Br, I).

Product Details of 67-51-6. Welcome to talk about 67-51-6, If you have any questions, you can contact Klein, M; Sundermeyer, J or send Email.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Recently I am researching about DAIRY MANURE; PY-GC/MS; TG-FTIR; COMBUSTION; CONVERSION; BIOOIL; TEMPERATURE; MECHANISM; KINETICS; LIGNIN, Saw an article supported by the National Key R&D Program of China [2016YFE0201800]; National Natural Science Foundation of ChinaNational Natural Science Foundation of China (NSFC) [51878557]. COA of Formula: C5H8N2. Published in ELSEVIER in AMSTERDAM ,Authors: He, SR; Cao, CC; Wang, JL; Yang, JZ; Cheng, ZJ; Yan, BB; Pan, Y; Chen, GY. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole

Cattle manure is a kind of abundant agriculture waste but potential renewable resource to be converted into fuel by pyrolysis. The pyrolysis behavior of cattle manure was analyzed by three methods in this work: thermogravimetric analyzer (TG), pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS) and pyrolysis photoionization time-of-flight mass spectrometry (Py-PI-TOFMS). The pyrolysis process of cattle manure included four stages, dehydration stage, lignocellulose decomposition stage, lignin and protein decomposition stage, char and mineral matter decomposition stage. The products were mainly classified into six groups: ketones, aldehydes, phenolic compounds, acids, hydrocarbons and N-containing compounds. Based on the time-evolved profiles and temperature-programmed profiles, the characteristics of these major products were analyzed and discussed. Maillard reaction has great effects on the pyrolysis process of cattle manure because cellulose can easily react with protein to produce abundant Amadori products and then generate cyclopentanes and furanmethanol. In addition, some Amadori products and amino acids can also be cyclized to generate N-heterocycle compounds like pyrroles and pyrazines. The decomposition of lignin basic units with more methoxy groups require higher reaction temperature, and the removal of hydroxy and methoxy group on phenols mainly occurred at around 350 degrees C. Furthermore, primary decomposition pathways of cattle manure were also proposed and discussed.

COA of Formula: C5H8N2. Welcome to talk about 67-51-6, If you have any questions, you can contact He, SR; Cao, CC; Wang, JL; Yang, JZ; Cheng, ZJ; Yan, BB; Pan, Y; Chen, GY or send Email.

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Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

An article Pyrazole-chalcone derivatives as selective COX-2 inhibitors: design, virtual screening, and in vitro analysis WOS:000472968400011 published article about DRUG DISCOVERY; CARDIOVASCULAR SAFETY; BIOLOGICAL-ACTIVITIES; LIBRARIES; BIOAVAILABILITY; COMBINATORIAL; PREDICTION in [Macarini, Anelise F.; Rizzi, Gerusa W.; Correa, Rogerio] Univ Vale Itajai, Nucleo Invest Quim Farmaceut NIQFAR, Rua Uruguai 458, BR-88302901 Itajai, SC, Brazil; [Macarini, Anelise F.; Correa, Rogerio] Univ Vale Itajai UNIVALI, Programa Posgrad Ciencias Farmaceut, Rua Uruguai 458, BR-88302901 Itajai, SC, Brazil; [Sobrinho, Thales U. C.; Correa, Rogerio] Univ Vale Itajai, Curso Engn Quim, Escola Mar Ciencia & Tecnol, Rua Uruguai 458, BR-88302901 Itajai, SC, Brazil in 2019.0, Cited 49.0. COA of Formula: C5H8N2. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6

In the process of research and development of new drugs, in silico analyzes are widely used. They address the pharmacokinetics of the molecules in study and can predict the binding mode and affinity, using a docking software. This approach can optimize the development of new drugs, reducing costs, time, and resources. In this study, a library of 300 pyrazole-chalcone derivatives were designed, the in silico ADMET (absorption, distribution, metabolism, excretion, and toxicity) properties were evaluated, and a structure-based virtual screening was performed using AutoDock Vina. The docking results exhibited that the derivatives binding mode at the COX-2 active site is similar to celecoxib, the reference drug, and presented similar binding energy. Six compounds were synthetized and tested for in vitro inhibition of the COX-1 and COX-2 isoenzymes and the selectivity index (SI) was calculated. The compound 2a11 showed the best activity for COX-2 (IC50COX-2=0.73M) whereas the control, celecoxib, resulted IC50COX-2=0.88M. All the other compounds synthetized presented better potency for COX-2 inhibition than the control. Compound 2a23 exhibited the higher SI, of 280.17 (IC50COX-1=210.13M/ IC50COX-2=0.75M), while celecoxib was 246.88 (IC50COX-1=217.26M/ IC50COX-2=0.88M). These results corroborate with a possible anti-inflammatory activity and COX-2 selectivity of the new compounds synthetized.

COA of Formula: C5H8N2. Welcome to talk about 67-51-6, If you have any questions, you can contact Macarini, AF; Sobrinho, TUC; Rizzi, GW; Correa, R or send Email.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

I found the field of Science & Technology – Other Topics very interesting. Saw the article Three host peculiarities of a cycloalkane-based micelle toward large metal-complex guests published in 2020.0. Recommanded Product: 3,5-Dimethyl-1H-pyrazole, Reprint Addresses Yoshizawa, M (corresponding author), Tokyo Inst Technol, Inst Innovat Res, Lab Chem & Life Sci, Midori Ku, 4259 Nagatsuta, Yokohama, Kanagawa 2268503, Japan.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole

Linear alkanes are essential building blocks for natural and artificial assemblies in water. As compared with typical, linear alkane-based micelles and recent aromatic micelles, we herein develop a cycloalkane-based micelle, consisting of bent amphiphiles with two cyclohexyl frameworks. This uncommon type of micelle, with a spherical core diameter of similar to 2nm, forms in water in a spontaneous and quantitative manner. The cycloalkane-based, hydrophobic cavity displays peculiar host abilities as follows: (i) highly efficient uptake of sterically demanding Zn(II)-tetraphenylporphyrin and rubrene dyes, (ii) selective uptake of substituted Cu(II)-phthalocyanines and spherical nanocarbons, and (iii) uptake-induced solution-state emission of [Au(I)-dimethylpyrazolate](3) in water. These host functions toward the large metal-complex and other guests studied herein remain unaccomplished by previously reported micelles and supramolecular containers.

Recommanded Product: 3,5-Dimethyl-1H-pyrazole. Welcome to talk about 67-51-6, If you have any questions, you can contact Hanafusa, M; Tsuchida, Y; Matsumoto, K; Kondo, K; Yoshizawa, M or send Email.

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Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

An article Energetically significant unconventional pi-pi contacts involving fumarate in a novel coordination polymer of Zn(II): In-vitro anticancer evaluation and theoretical studies WOS:000471754200001 published article about METAL-ORGANIC FRAMEWORKS; CRYSTAL-STRUCTURE; SUPRAMOLECULAR ASSOCIATION; STRUCTURAL-CHARACTERIZATION; LIGANDS SYNTHESIS; HOLE INTERACTION; ZINC-COMPLEXES; DNA-BINDING; PYRAZOLE; CU(II) in [Gogoi, Anshuman; Das, Amal; Bhattacharyya, Manjit K.] Cotton Univ, Dept Chem, Gauhati 781001, Assam, India; [Frontera, Antonio] Univ Illes Balears, Dept Quim, Crta Valldemossa Km 7-7, Palma De Mallorca 07122, Baleares, Spain; [Verma, Akalesh K.] Cotton Univ, Dept Zool, Cell & Biochem Technol Lab, Gauhati 781001, Assam, India in 2019.0, Cited 96.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. HPLC of Formula: C5H8N2

A new fumarato bridged Zn(II) coordination polymer viz. catena[mu-fumaratobis(3,5-dimethylpyrazole)zinc(II) trihydrate],{[Zn-2(mu-fum)(2)(Hdmpz)(4)]center dot 3H(2)O}(n) (1) (where, fum = fumarate, Hdmpz = 3,5-dimethylpyrazole) has been synthesized in purely aqueous medium at room temperature. The compound is structurally characterized by single crystal X-ray diffraction, FT-IR, electronic spectroscopy, PXRD and TGA. The zig-zag polymeric chain of 1 self assembles into a 2D supramolecular network via C-H center dot center dot center dot pi, C-H center dot center dot center dot C, N-H-center dot center dot center dot O and C-H center dot center dot center dot O interactions. Particularly relevant in 1, since in addition to the aforementioned non-covalent interactions, the electron rich pi-system of fumarate is involved in energetically significant unconventional pi-pi contacts with the electron poor pi-cloud of Hdmpz, which have been analyzed by DFT calculations and characterized using the non-covalent interaction (NCI) plot index. The strong H-bond agrees well with the MEP analysis since it is established between the H-bond donor involving NH group of Hdmpz and the H-bond acceptor involving O-atom of carboxylate moiety. The compound has been investigated for anticancer activities considering cell cytotoxicity, apoptosis and molecular docking as parameters in Dalton’s lymphoma (DL) malignant cancer cell line and results were compared with cisplatin (reference drug) under the same experimental conditions. Interestingly, negligible cytotoxic effect was observed against normal cells (PBMC) in comparison to the cancer cells (DL). The treatment of the compound caused appearance of apoptotic cells as evident by fluorescence based nuclear morphology study. The in silica study reveals that the compound interacts with the antiapoptotic proteins such as bcl-2, bcl-XL and Mcl-1 which may lead to apoptotic cell death.

Welcome to talk about 67-51-6, If you have any questions, you can contact Gogoi, A; Das, A; Frontera, A; Verma, AK; Bhattacharyya, MK or send Email.. HPLC of Formula: C5H8N2

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

I found the field of Chemistry very interesting. Saw the article Metal-free, Mild, and Selective Synthesis of Bis(pyrazolyl)alkanes by Nucleophile-Catalyzed Condensation published in 2021. Name: 3,5-Dimethyl-1H-pyrazole, Reprint Addresses Comito, RJ (corresponding author), Univ Houston, Houston, TX 77004 USA.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole

Bis(pyrazolyl)alkanes are a prolific class of ligands for catalysis, accessible by the condensation between bis(pyrazolyl)methanones and carbonyls. In this report, we describe a nucleophile-catalyzed innovation on this condensation that avoids the transition metals, high temperatures, reagent excess, and air-sensitive reagents common among the existing protocols. Significantly, this method accommodates sterically hindered and electronically diverse pyrazoles and aldehydes, applicable for systematic ligand optimization. Furthermore, our scope includes azoles and bridging functional groups previously unreported for this reaction, promising for new heteroscorpionate catalysts. We provide the first direct evidence for an elusive reaction intermediate and characterize the most complete mechanism for this condensation.

Name: 3,5-Dimethyl-1H-pyrazole. Bye, fridends, I hope you can learn more about C5H8N2, If you have any questions, you can browse other blog as well. See you lster.

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Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

An article Monomeric zinc ferrocene carboxylate [Zn(FcCOO)(3,5-dmp)(2)Cl] derived from 3,5-dimethylpyrazole: structural, optical, electrochemical and antimicrobial studies WOS:000609159900008 published article about BIOORGANOMETALLIC CHEMISTRY; CRYSTAL-STRUCTURE; METAL-COMPLEXES; AMINO-ACIDS; DERIVATIVES; PYRAZOLE in [Champaka, Gurudevaru; Senthilkumar, Kabali; David, Ezhumalai; Palanisami, Nallasamy] Vellore Inst Technol, Ctr Funct Mat, Dept Chem, Sch Adv Sci, Vellore 632014, Tamil Nadu, India; [Shanmugan, Swaminathan] SRM Inst Sci & Technol, Dept Chem, Fac Engn & Technol, Kancheepuram 603203, Tamil Nadu, India in 2021.0, Cited 40.0. Safety of 3,5-Dimethyl-1H-pyrazole. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6

Monomeric zinc ferrocene carboxylate [Zn(FcCOO)(3,5-dmp)(2)Cl] (1) has been synthesized from a reaction between the zinc chloride, sodium salt of ferrocene carboxylic acid (FcCOONa) and 3,5-dimethylpyrazole (3,5-dmp) at room temperature. Compound 1 was further characterized by elemental analysis, H-1 NMR, FT-IR, absorption, emission spectroscopic techniques, and molecular structure was confirmed by single-crystal X-ray diffraction studies. The molecular structure of compound 1 crystallized in triclinic system with P (1) over bar space group and the central Zn2+ ion is in a distorted tetrahedral geometry with -FeN2OCl coordination environment. Compound 1 was further stabilized with the aid of inter and intramolecular hydrogen bonding and pi-pi interaction between cyclopentadienyl ring of ferrocene and aromatic heterocyclic five membered 3,5-dimethylpyrazole. Compound 1 exhibits broad emission band, indicating ligandto-metal charger transfer (LMCT) or metal-to-ligand charger transfer (MLCT) nature. The electrochemical property of compound 1 revealed that one-electron anodic and cathodic peaks corresponding to the redox responsible of ferrocene/ferrocenium (FeII <-> Fe-III) moiety. Among the different strains of bacteria, the antibacterial activity of compound 1 showed comparatively a significant activity against gram negative bacterium Proteus vulgaris. (C) 2020 Elsevier B.V. All rights reserved.

Safety of 3,5-Dimethyl-1H-pyrazole. Bye, fridends, I hope you can learn more about C5H8N2, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

An article Crystal structure of bis{(3,5-dimethylpyrazol-1-yl)dihydro[3-(pyridin-2-yl)pyrazol-1-yl]borato}iron(II) WOS:000569355400017 published article about SPIN-CROSSOVER; MAGNETIC-PROPERTIES; IRON(II) COMPLEXES; STATE; POLYMORPHISM; TEMPERATURE; TRANSITION; PYRAZOLYL; CHEMISTRY; CONTACT in [Ossinger, Sascha; Naether, Christian; Tuczek, Felix] Christian Albrechts Univ Kiel, Inst Anorgan Chem, Max Eyth Str 2, D-24118 Kiel, Germany in 2020.0, Cited 44.0. Recommanded Product: 67-51-6. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6

The structure determination of [Fe(C13H15BN5)(2)] was undertaken as part of a project on the modification of the recently published spin-crossover (SCO) complex [Fe{H2B(pz)(pypz)}(2)] (pz = pyrazole, pypz = pyridylpyrazole). To this end, a new ligand was synthesized in which two additional methyl groups are present. Its reaction with iron trifluoromethanesulfonate led to a pure sample of the title compound, as proven by X-ray powder diffraction. The asymmetric unit consists of one complex molecule in a general position. The Fe-II atom is coordinated by two tridentate N-binding {H2B(3,5-(CH3)(2)-pz)(pypz)}(-) ligands. The Fe-N bond lengths range between 2.1222 (13) and 2.3255 (15) angstrom, compatible with Fe-II in the high-spin state, which was also confirmed by magnetic measurements. Other than a very weak C-H center dot center dot center dot N non-classical hydrogen bond linking individual molecules into rows extending parallel to [010], there are no remarkable intermolecular interactions.

Welcome to talk about 67-51-6, If you have any questions, you can contact Ossinger, S; Nather, C; Tuczek, F or send Email.. Recommanded Product: 67-51-6

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

I found the field of Crystallography very interesting. Saw the article Crystal structure of bis{(3,5-dimethylpyrazol-1-yl)dihydro[3-(pyridin-2-yl)pyrazol-1-yl]borato}iron(II) published in 2020.0. Application In Synthesis of 3,5-Dimethyl-1H-pyrazole, Reprint Addresses Ossinger, S (corresponding author), Christian Albrechts Univ Kiel, Inst Anorgan Chem, Max Eyth Str 2, D-24118 Kiel, Germany.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole

The structure determination of [Fe(C13H15BN5)(2)] was undertaken as part of a project on the modification of the recently published spin-crossover (SCO) complex [Fe{H2B(pz)(pypz)}(2)] (pz = pyrazole, pypz = pyridylpyrazole). To this end, a new ligand was synthesized in which two additional methyl groups are present. Its reaction with iron trifluoromethanesulfonate led to a pure sample of the title compound, as proven by X-ray powder diffraction. The asymmetric unit consists of one complex molecule in a general position. The Fe-II atom is coordinated by two tridentate N-binding {H2B(3,5-(CH3)(2)-pz)(pypz)}(-) ligands. The Fe-N bond lengths range between 2.1222 (13) and 2.3255 (15) angstrom, compatible with Fe-II in the high-spin state, which was also confirmed by magnetic measurements. Other than a very weak C-H center dot center dot center dot N non-classical hydrogen bond linking individual molecules into rows extending parallel to [010], there are no remarkable intermolecular interactions.

About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Ossinger, S; Nather, C; Tuczek, F or concate me.. Application In Synthesis of 3,5-Dimethyl-1H-pyrazole

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Fu, H; Wang, XY; Sang, HN; Fan, RY; Han, YF; Zhang, JL; Liu, ZZ in [Fu, Hui; Wang, Xinyu; Sang, Haina; Fan, Ruoyao; Han, Yufen; Zhang, Jialu; Liu, Zhenzhen] China Univ Petr, Coll Sci, Qingdao 266580, Peoples R China published The study of bicyclic amidine-based ionic liquids as promising carbon dioxide capture agents in 2020.0, Cited 35.0. Category: pyrazoles-derivatives. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.

CO2 capture by ionic liquids has been successfully achieved, indicating that the adsorption of CO2 plays an important role in the activation and transformation of CO2. In this work, highly efficient capture of CO2 is investigated with several novel ILs, which were prepared from bicyclic amidine (DBN) with pyrazole derivatives. Among the kinds of DBN-based ILs, it is found that the optimal absorption capacity (0.93 mol CO2/mol IL) can be achieved by [DBNH][3-MethylPyr] at 40 degrees C and atmospheric pressure. In view of analysis, the significant increase in CO2 capacity was affected by the reactivity of activated nitrogen, steric hindrance and the type of substituents. On the basis of the spectroscopic investigation and Density Functional Theory (DFT) calculation, the absorption mechanism was illustrated, it was verified that anions can react with CO2 to form carbamates. Meanwhile, charge analysis reasonably elucidated the diversity of absorption capacity in various ILs. It suggested that electric-charge distribution of activated nitrogen in pyrazole ring system can play an important role in determining the reaction of ILs with CO2. Consequently, DBN-based ILs can be excellent candidates for CO2 capture. (C) 2020 Elsevier B.V. All rights reserved.

Category: pyrazoles-derivatives. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Fu, H; Wang, XY; Sang, HN; Fan, RY; Han, YF; Zhang, JL; Liu, ZZ or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics