Category: 67-51-6

COA of Formula: C5H8N2. In 2020.0 INORG CHEM published article about DENSITY-FUNCTIONAL THEORY; RHENIUM(I) TRICARBONYL COMPLEXES; TRANSITION-METAL-COMPLEXES; EFFECTIVE CORE POTENTIALS; PROTON RESPONSIVE LIGAND; ACID-BASE PROPERTIES; EXCITED-STATE; RE(I) COMPLEXES; CHARGE-TRANSFER; CARBON-DIOXIDE in [Merillas, Beatriz; Cuellar, Elena; Martin-Alvarez, Jose M.; Miguel, Daniel; Villafane, Fernando] Univ Valladolid, Fac Ciencias, GIR MIOMeT IU Cinquima Quim Inorgan, Campus Miguel Delibes, Valladolid 47011, Spain; [Diez-Varga, Alberto; Torroba, Tomas; Garcia-Herbosa, Gabriel] Univ Burgos, Fac Ciencias, Dept Quim, Burgos 09001, Spain; [Fernandez, Sergio; Lloret-Fillol, Julio] Barcelona Inst Sci & Technol, Inst Chem Res Catalonia ICIQ, Tarragona 43007, Spain; [Lloret-Fillol, Julio] Catalan Inst Res & Adv Studies ICREA, Barcelona 08010, Spain in 2020.0, Cited 100.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.

Cationic fac-[Re(CO)(3)(pz*H)(pypzH)]OTf (pz*H = pyrazole, pzH; 3,5-dimethylpyrazole, dmpzH; indazole, indzH; 3-(2-pyridyl)pyrazole, pypzH) were obtained from fac[ReBr(CO)(3)(pypzH)] by halide abstraction with AgOTf and subsequent addition of the corresponding pyrazole. Successive deprotonation with Na2CO3 and NaOH gave neutral fac[Re(CO)(3)(pz*H)(pypz)] and anionic Na{fac-[Re(CO)(3)(pz*)(pypz)]} complexes, respectively. Cationic fac-[Re(CO)(3)(pz*H)(pypzH)]OTf, neutral complexes fac-[Re(CO)(3)(pz*H)(pypz)], and fac-[Re(CO)(3)(pypz)(2)Na] were subjected to photophysical and electrochemical studies. They exhibit phosphorescent decays from a prevalently (MLCT)-M-3 excited state with quantum yields (F) in the range between 0.03 and 0.58 and long lifetimes (tau from 220 to 869 ns). The electrochemical behavior in Ar atmosphere of cationic and neutral complexes indicates that the oxidation processes assigned to Re-I -> Re-II occurs at lower potentials for the neutral complex compared to cationic complex. The reduction processes occur at the ligands and do not depend on the charge of the complexes. The electrochemical behavior in CO2 saturated media is consistent with CO2 electrocatalyzed reduction, where the values of the catalytic activity [i(cat)(CO2)/i(cat)(Ar)] ranged from 2.7 to 11.5 (compared to 8.1 for fac-[Re(CO)(3)Cl(bipy)] studied as a reference). Controlled potential electrolysis for the pyrazole cationic (3a) and neutral (4a) complexes after 1 h affords CO in faraday yields of 61 and 89%, respectively. These values are higher for indazole complexes and may be related to the acidity of the coordinated pyrazole.

About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Merillas, B; Cuellar, E; Diez-Varga, A; Torroba, T; Garcia-Herbosa, G; Fernandez, S; Lloret-Fillol, J; Martin-Alvarez, JM; Miguel, D; Villafane, F or concate me.. COA of Formula: C5H8N2

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

In 2020.0 ANGEW CHEM INT EDIT published article about DIELS-ALDER; ENANTIOSELECTIVE FLUORINATION; CRYSTAL-STRUCTURE; CATION; PROPIOLOYLPYRAZOLES; CYCLOADDITION; ACYLPYRAZOLES; DESIGN; ROUTE; SET in [Ishihara, Kazuaki; Nishimura, Kazuki; Yamakawa, Katsuya] Nagoya Univ, Grad Sch Engn, Chikusa Ku, B2-3 611,Furo Cho, Nagoya, Aichi 4648603, Japan in 2020.0, Cited 49.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. Application In Synthesis of 3,5-Dimethyl-1H-pyrazole

Catalytic enantioselective alpha-fluorination reactions of carbonyl compounds are among the most powerful and efficient synthetic methods for constructing optically active alpha-fluorinated carbonyl compounds. Nevertheless, alpha-fluorination of alpha-nonbranched carboxylic acid derivatives is still a big challenge because of relatively high pK(a)values of their alpha-hydrogen atoms and difficulty of subsequent synthetic transformation without epimerization. Herein we show that chiral copper(II) complexes of 3-(2-naphthyl)-l-alanine-derived amides are highly effective catalysts for the enantio- and site-selective alpha-fluorination ofN-(alpha-arylacetyl) andN-(alpha-alkylacetyl) 3,5-dimethylpyrazoles. The substrate scope of the transformation is very broad (25 examples including a quaternary alpha-fluorinated alpha-amino acid derivative). alpha-Fluorinated products were converted into the corresponding esters, secondary amides, tertiary amides, ketones, and alcohols with almost no epimerization in high yield.

About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Ishihara, K; Nishimura, K; Yamakawa, K or concate me.. Application In Synthesis of 3,5-Dimethyl-1H-pyrazole

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

COA of Formula: C5H8N2. I found the field of Chemistry very interesting. Saw the article The development of a Cu(I)/pyrazolylpyridineamine catalyst system for the hydroxylation of aryl halides published in 2020.0, Reprint Addresses Swarts, AJ (corresponding author), North West Univ, Focus Area Chem Resource Beneficiat, Catalysis & Synth Res Grp, 11 Hoffman St, ZA-2520 Potchefstroom, South Africa.. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole.

A catalyst system comprising of pyrazolylpyridineamine/Cu(I)/CsOH is reported. for the hydroxylation of aryl iodides and bromides with moderate to outstanding yields, without the use of an inert atmosphere. A comprehensive parameter optimisation study established optimum component concentrations: [Cu(MeCN)(4)]BF4 and 2-(1H-pyrazol-1-yl)-N-(pyridine-2-ylmethyl)ethan-1-amine (L01) (2 mol %), substrate (1 mmol), CsOH (4 mmol) and DMSO:H2O (1:1, 3 mL). Monitoring substrate conversion as a function of time revealed an induction period of 90 min, which could be eliminated through the initial in situ formation of the proposed [(L01)Cu-OH] intermediate. Eliminating the induction period resulted in complete conversion within one hour, with turnover numbers exceeding that of the benchmark catalyst system operating at an optimal catalyst loading of 0.05 mol %.

COA of Formula: C5H8N2. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Marais, L; Vosloo, HCM; Swarts, AJ or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

In 2020.0 EUR UROL FOCUS published article about RESISTANCE in [Cimino, Sebastiano; Verze, Paolo; Venturino, Luca; Alessio, Paolo; Migliara, Alfonso; Imbimbo, Ciro; Mirone, Vincenzo; Russo, Giorgio Ivan; Morgia, Giuseppe] Univ Catania, Dept Urol, Urol Sect, Catania, Italy; [Cimino, Sebastiano; Verze, Paolo; Venturino, Luca; Alessio, Paolo; Migliara, Alfonso; Imbimbo, Ciro; Mirone, Vincenzo; Russo, Giorgio Ivan; Morgia, Giuseppe] Univ Naples Federico II, Dept Neurosci Reprod Sci & Odontostomatol, Naples, Italy in 2020.0, Cited 18.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. COA of Formula: C5H8N2

Background: Transrectal ultrasound-guided prostate biopsy (TRBx) or transperineal Bx (TPBx) are considered alternative approaches for the diagnosis of prostate cancer (PCa). However, urinary tract infection (UTI) or other complications could be more frequent in the TRBx approach. Objective: To determine the complication rate following different antimicrobial prophylaxis (AMP; fosfomycin trometamol [FT] vs beta-lactame or fluorochinolones [FQ]) in patients undergoing TRBx or TPBx. Design, setting, and participants: The analyses were based on prospectivelycollected data of a cohort of patients who underwent TRBx or TPBx for elevated prostate-specific antigen (PSA; >= 4 ng/ml) or clinical suspicion of PCa, between September 2016 and March 2017. Patients received a single dose of 3 g oral FT (group A) or, alternatively, FQ or beta-lactame (group B). Intervention:TRBx versus TPBx. Outcome measurements and statistical analysis: Adjustment variables consisted of age, PSA, biopsy technique (TPBx vs TRBx), and antibiotic prophylaxis (FT vs beta-lactame or FQ) using 1:1 propensity-score matching. Overall, 526 patients were considered, of whom 258 received FT (group A) and the other 258 received beta-lactame or FQ (group B). Results and limitations: Overall complications occurred in 390 (75.58%) and major complications in 67/516 (12.98%). Lower prevalence of UTIs was detected in group A (34.1%) compared with that in group B (43.4%; p = 0.03), while similar rates of haematuria (54.7% vs 55.4%), haemospermia (39.5% vs 33.0%), and acute urinary retention (11.6% vs 9.3%) were detected in groups A and B. We found that group B (odds ratio [OR]: 1.54; p = 0.03), I grade haematuria (OR: 6.17; p < 0.01), and II grade haematuria (OR: 5.13; p < 0.01) were significantly associated with increased risk of UTIs. Conclusions: AMP with fluoroquinoles or beta-lactam antibiotics increased the rate of UTIs, when compared with FT, in patients undergoing TRBx or TPBx. The appearance of haematuria or haemospermia is associated with UTIs, suggesting the possibility of tailoring the strategy for prophylaxis in this category of patients. Patient summary: In this study, comparing complications after transrectal ultrasound-guided prostate biopsy versus transperineal biopsy, prophylaxis with fluoroquinoles or beta-lactam antibiotics increased the rate of urinary tract infections when compared with fosfomycin trometamol, regardless of the type of biopsy approach. (C) 2018 European Association of Urology. Published by Elsevier B.V. All rights reserved. COA of Formula: C5H8N2. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Cimino, S; Verze, P; Venturino, L; Alessio, P; Migliara, A; Imbimbo, C; Mirone, V; Russo, GI; Morgia, G or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Name: 3,5-Dimethyl-1H-pyrazole. In 2020.0 CHEM-EUR J published article about LANTHANIDE COMPLEXES; UNIQUE EMISSION; METAL; CHEMISTRY; SILYLAMIDE; OXIDATION; BEARING; LUMINESCENCE; COORDINATION; EQUILIBRIUM in [Werner, Daniel; Bayer, Uwe; Schaedle, Dorothea; Anwander, Reiner] Univ Tubingen EKUT, Inst Anorgan Chem, Morgenstelle 18, D-72076 Tubingen, Germany in 2020.0, Cited 104.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.

The cerium(IV) pyrazolate complexes [Ce(Me(2)pz)(4)](2)and [Ce(Me(2)pz)(4)(thf)] initiate beta-hydride abstraction of the bis(dimethylsilyl)amido moiety, to afford a heteroleptic cerium(IV) species containing a dimethylpyrazolyl-substituted silylamido ligand, namely [Ce(Me(2)pz)(3)(bpsa)] (bpsa=bis((3,5-dimethylpyrazol-1-yl)dimethylsilyl)amido; Me(2)pz =3,5-dimethylpyrazolato), along with some cerium(III) species. Remarkably, the nucleophilic attack of the pyrazolyl at the silicon atom and concomitant Si-H-bond cleavage is restricted to the tetravalent cerium oxidation state and appears to proceed via the formation of a transient cerium(IV) hydride, which engages in immediate redox chemistry. When [Ce(Me(2)pz)(4)](2)is treated with [Li{N(SiMe3)(2)}], that is, in the absence of the SiH functionality, any redox chemistry did not occur. Instead, the ceric ate complex [LiCe2(Me(2)pz)(9)] and the stable mixed-ligand ceric species [Ce(Me(2)pz)(2){N(SiMe3)(2)}(2)] were obtained.

Name: 3,5-Dimethyl-1H-pyrazole. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Werner, D; Bayer, U; Schadle, D; Anwander, R or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

In 2019 TETRAHEDRON published article about C-H AMINATION; CARBON-NITROGEN BONDS; 1-NAPHTHYLAMINE DERIVATIVES; 8-AMINOQUINOLINE AMIDES; C5-H PHOSPHONATION; ARYL HALIDES; ACTIVATION; QUINOLINES; STRATEGY; SCOPE in [Ma, Yueyue; Shi, Yaqi; Yang, Fan; Wu, Yangjie] Zhengzhou Univ, Key Lab Appl Chem Henan Univ, Henan Key Lab Chem Biol & Organ, Coll Chem & Mol Engn, Zhengzhou 450052, Henan, Peoples R China; [Wu, Yusheng] TetranovBiophann LLC, Zhengzhou 450001, Henan, Peoples R China; [Wu, Yusheng] Collaborat Innovat Ctr New Drug Res & Safety Eval, Zhengzhou 450001, Henan, Peoples R China in 2019, Cited 35. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. HPLC of Formula: C5H8N2

A practical and efficient protocol for Ag/Ru-cocatalyzed regioselective C-H amination of 8-hydroxyquinoline esters with pyrazoles was developed, This reaction proceeded smoothly via a photoredox-mediated direct C-H/N-H oxidative coupling process. The remarkable features of this reaction include the wide substrate scope, mild reaction conditions and high regioselectivity at the C4 site of the quinolinyl moiety. (C) 2019 Elsevier Ltd. All rights reserved.

HPLC of Formula: C5H8N2. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Ma, YY; Shi, YQ; Yang, F; Wu, YS; Wu, YJ or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Authors Zhang, FL; Zhou, PC; Zhang, SL; Li, YY; Zhang, QF; Guo, WL; Huang, J; Wang, WY; Dong, Z; Wei, B; Wei, DH; Cao, GX; Zhai, B in ELSEVIER published article about in [Zhang, Fuli; Zhang, Shulin; Li, Yuanyang; Zhang, Quanfeng; Guo, Wenlong; Huang, Jing; Wang, Wenyu; Dong, Zhen; Cao, Guangxiu; Zhai, Bin] Shangqiu Normal Univ, Coll Chem & Chem Engn, Engn Tech Res Ctr Optoelect Funct Mat Henan Prov, Key Lab Biomol Recognit & Sensing Henan Prov, Shangqiu 476000, Peoples R China; [Zhou, Pengchao; Wei, Bin] Shanghai Univ, Sch Mechatron Engn & Automat, Key Lab Adv Display & Syst Applicat, Minist Educ, Shanghai 200072, Peoples R China; [Wei, Donghui] Zhengzhou Univ, Coll Chem & Mol Engn, Zhengzhou 450001, Peoples R China in 2021.0, Cited 66.0. Recommanded Product: 3,5-Dimethyl-1H-pyrazole. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6

In this work, we report three deep-blue emitting cationic iridium complexes Ir1-Ir3 with 2′,6′-difluoro-2,3′-bipyridine cyclometalated ligand and pyrazole-type ancillary ligands. Synthesis, crystal structure, photophysical and electrochemical properties of Ir1-Ir3 are studied in detail. Ir1-Ir3 exhibit efficient phosphorescence emissions at 439, 438 and 437 nm with CIE 1931 coordinates of (0.14, 0.12), (0.14, 0.12) and (0.14, 0.13), and luminescence quantum yields of 0.35, 0.27 and 0.50 in CH2Cl2 solutions, respectively, which are among the highest levels of ever reported cationic iridium(III) complexes emitting deep-blue light. High luminescence quantum yields, excellent color purity and short lifetimes demonstrates the great potential of Ir1-Ir3 for lightemitting electrochemical cells (LECs) and solution-processable organic light-emitting diodes (OLEDs) as efficient blue emitters.

About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Zhang, FL; Zhou, PC; Zhang, SL; Li, YY; Zhang, QF; Guo, WL; Huang, J; Wang, WY; Dong, Z; Wei, B; Wei, DH; Cao, GX; Zhai, B or concate me.. Recommanded Product: 3,5-Dimethyl-1H-pyrazole

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

An article Atroposelective Synthesis of Axially Chiral N-Arylpyrroles by Chiral-at-Rhodium Catalysis WOS:000537136800001 published article about ACID; ALCOHOLS; LIGANDS in [Ye, Chen-Xi; Han, Feng; Xie, Xiulan; Ivlev, Sergei; Meggers, Eric] Philipps Univ Marburg, Fachbereich Chem, Hans Meerwein Str 4, D-35043 Marburg, Germany; [Chen, Shuming; Houk, K. N.] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA in 2020.0, Cited 29.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. HPLC of Formula: C5H8N2

A transformation of fluxional into configurationally stable axially chiral N-arylpyrroles was achieved with a highly atroposelective electrophilic aromatic substitution catalyzed by a chiral-at-metal rhodium Lewis acid. Specifically, N-arylpyrroles were alkylated with N-acryloyl-1H-pyrazole electrophiles in up to 93 % yield and with up to >99.5 % ee, and follow-up conversions reveal the synthetic utility of this new method. DFT calculations elucidate the origins of the observed excellent atroposelectivity.

HPLC of Formula: C5H8N2. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Ye, CX; Chen, SM; Han, F; Xie, XL; Ivlev, S; Houk, KN; Meggers, E or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Recommanded Product: 67-51-6. In 2020.0 J ANAL APPL PYROL published article about DAIRY MANURE; PY-GC/MS; TG-FTIR; COMBUSTION; CONVERSION; BIOOIL; TEMPERATURE; MECHANISM; KINETICS; LIGNIN in [He, Sirong; Cao, Congcong; Wang, Jinglan; Cheng, Zhanjun; Yan, Beibei] Tianjin Univ, Sch Environm Sci & Engn, Tianjin 300072, Peoples R China; [Yang, Jiuzhong; Pan, Yang] Univ Sci & Technol China, Natl Synchrotron Radiat Lab, Hefei 230029, Anhui, Peoples R China; [Cheng, Zhanjun; Yan, Beibei] Tianjin Univ, Tianjin Engn Res Ctr Organ Wastes Safe Disposal &, Tianjin Key Lab Biomass Waste Utilizat, Key Lab Efficient Utilizat Low & Medium Energy, Tianjin 300072, Peoples R China; [Chen, Guanyi] Tianjin Univ Commerce, Sch Mech Engn, Tianjin 300134, Peoples R China in 2020.0, Cited 38.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6.

Cattle manure is a kind of abundant agriculture waste but potential renewable resource to be converted into fuel by pyrolysis. The pyrolysis behavior of cattle manure was analyzed by three methods in this work: thermogravimetric analyzer (TG), pyrolysis-gas chromatography/mass spectrometry (Py-GC/MS) and pyrolysis photoionization time-of-flight mass spectrometry (Py-PI-TOFMS). The pyrolysis process of cattle manure included four stages, dehydration stage, lignocellulose decomposition stage, lignin and protein decomposition stage, char and mineral matter decomposition stage. The products were mainly classified into six groups: ketones, aldehydes, phenolic compounds, acids, hydrocarbons and N-containing compounds. Based on the time-evolved profiles and temperature-programmed profiles, the characteristics of these major products were analyzed and discussed. Maillard reaction has great effects on the pyrolysis process of cattle manure because cellulose can easily react with protein to produce abundant Amadori products and then generate cyclopentanes and furanmethanol. In addition, some Amadori products and amino acids can also be cyclized to generate N-heterocycle compounds like pyrroles and pyrazines. The decomposition of lignin basic units with more methoxy groups require higher reaction temperature, and the removal of hydroxy and methoxy group on phenols mainly occurred at around 350 degrees C. Furthermore, primary decomposition pathways of cattle manure were also proposed and discussed.

Recommanded Product: 67-51-6. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact He, SR; Cao, CC; Wang, JL; Yang, JZ; Cheng, ZJ; Yan, BB; Pan, Y; Chen, GY or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Recently I am researching about 2+2 PHOTOCYCLOADDITION REACTIONS; PHOTOREDOX CATALYSIS; BRONSTED ACID; THIOXANTHONE; ALKYLATION; ELECTRON; ACTIVATION; AMINATION; THIOUREA, Saw an article supported by the ICSN; CNRSCentre National de la Recherche Scientifique (CNRS)European Commission; China Scholarship CouncilChina Scholarship Council. Published in AMER CHEMICAL SOC in WASHINGTON ,Authors: Lyu, JY; Claraz, A; Vitale, MR; Allain, C; Masson, G. The CAS is 67-51-6. Through research, I have a further understanding and discovery of 3,5-Dimethyl-1H-pyrazole. Recommanded Product: 3,5-Dimethyl-1H-pyrazole

Chiral phosphoric acid based organocatalysis and visible-light photocatalysis have both emerged as promising technologies for the sustainable production of fine chemicals. In this context, we have envisioned the design and the synthesis of a new class of chimeric catalytic entities that would feature both catalytic capabilities. Given their multitask nature, such catalysts would be particularly attractive for the development of new catalytic transformations, tandem processes in particular. Toward this goal, several BINOL-based chiral phosphoric acid backbones presenting one or two visible-light-sensitive thioxanthone moieties have been prepared and studied. The utility of these new photoactive chiral organocatalysts is then demonstrated in the enantioselective tandem three-component electrophilic amination of enecarbamates. Of note, the C-1-symmetric organo/photocatalyst has shown a better catalytic activity than those presenting a C-2 symmetry.

Recommanded Product: 3,5-Dimethyl-1H-pyrazole. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Lyu, JY; Claraz, A; Vitale, MR; Allain, C; Masson, G or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics