Category: 930-36-9

Li, Weipeng published the artcileCooperative Au/Ag Dual-Catalyzed Cross-Dehydrogenative Biaryl Coupling: Reaction Development and Mechanistic Insight, Synthetic Route of 930-36-9, the publication is Journal of the American Chemical Society (2019), 141(7), 3187-3197, database is CAplus and MEDLINE.

In the presence of (Me₂S)AuCl and AgOAc, pyrazoles such as 1-phenylpyrazole underwent chemoselective and regioselective oxidative dehydrogenative coupling reactions with fluorinated arenes and pyridines such as 2,3,5,6-tetrafluoropyridine mediated by PhI(OAc)₂ in 1,4-dioxane to yield (fluoroaryl)pyrazoles such as I. The mechanism of the oxidative coupling reaction was studied by determination of the reaction kinetics, kinetic isotope effects, and deuterium exchange, by generation and preparation of gold and silver complexes as potential intermediates, and by DFT calculations of transition state structures and energies for arene metalation, transmetalation, and reductive elimination reactions. Silver acetate is determined to be is the actual catalyst for C-H activation of electron-poor arenes, rather than gold(I) complexes. A mechanism of gold/silver dual catalysis is proposed, in which silver is responsible for the activation of electron-poor fluoroarenes via a concerted metalation-deprotonation pathway, and gold is responsible for the activation of electron-rich pyrazoles via an electrophilic aromatic substitution process. Kinetic studies reveal that C-H activation of pyrazoles by fluoroarylgold complexes is most likely the rate-limiting step.

Journal of the American Chemical Society published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, Synthetic Route of 930-36-9.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Zhu, Xinrui published the artcileOne-step preparation of ammonium-specified pyrazolium ionic liquids unveil the more popular pathway for the CO₂ fixation: Integrated experimental and theoretical studies, COA of Formula: C4H6N2, the publication is Journal of Molecular Liquids (2021), 115435, database is CAplus.

Amino-specified pyrazolium ionic liquid (APEPzBr) is synthesized by two steps. It is interesting that the product of the first step ([EPzPNH₃]Br₂) could also catalyze the coupling reaction of carbon dioxide and epoxides under 70°C along with 0.5 MPa CO₂ pressure, which is even more benign than APEPzBr. It is attributed to the strong ability of [EPzPNH₃]Br₂ to absorb CO2 along with robust electrophilic activation, which is testified by d. functional theory and ¹³C NMR measurement. The difference between [EPzPNH₃]Br₂ and APEPzBr is further elucidated by electron localization function (ELF) and atoms in mols. (AIM).

Journal of Molecular Liquids published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C19H42F6NP, COA of Formula: C4H6N2.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Dong, Dawei published the artcileCrosslinked anion exchange membranes with regional intensive ion clusters prepared from quaternized branched polyethyleneimine/quaternized polysulfone, Product Details of C4H6N2, the publication is International Journal of Hydrogen Energy (2022), 47(59), 24991-25006, database is CAplus.

A series of anion exchange membranes (AEMs) with regionally dense ion clusters are prepared by crosslinking quaternized polysulfone (QPSU) with quaternized branched polyethyleneimine (QBPEI). For the as-prepared QPSU/QBPEI AEMs, the hydrophilic QBPEI forms locally aggregated ion clusters in the QPSU matrix, which can promote the formation of an obvious microphase separation structure in the membrane. The QPSU/QBPEI-3 AEM with an ion exchange capacity of 1.88 meq/g exhibits the best performance, achieving a reasonably high ionic conductivity of 66.14 mS/cm at 80°C and showing good oxidation stability and alkali resistance. Finally, the maximum power d. of a single H₂/O₂ fuel cell with QPSU/QBPEI-3 AEM reaches 75.34 mW/cm² at 80°C. The above results indicate that QBPEI with a dendritic structure and abundant anionic conductive groups has a good application prospect in the preparation of AEMs with locally aggregated ion clusters and microphase separation structures.

International Journal of Hydrogen Energy published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, Product Details of C4H6N2.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Cai, Dongren published the artcileDesign and synthesis of novel Bronsted-Lewis acidic ionic liquid and its application in biodiesel production from soapberry oil, Related Products of pyrazoles-derivatives, the publication is Energy Conversion and Management (2018), 318-327, database is CAplus.

With the combination of mol. simulation and relevant experiments, the efficient Bronsted-Lewis acidic ionic liquid (IL) was designed and synthesized for biodiesel production from soapberry oil. In mol. simulation, 4-methylthiazole (MT) is proved to be the best matrix for IL preparation via electrostatic potential anal. and proton affinity anal., and it also is verified by experiments In orthogonal experiment, the relationship in catalytic activity between Bronsted-Lewis acidic IL and corresponding materials (Bronsted acidic IL and metal chloride) was revealed. Meanwhile, [Ps-MTH][CF₃SO₃] and FeCl₃ are verified as the best materials for preparation of Bronsted-Lewis acidic IL, and [Ps-MTH][CF₃SO₃]-FeCl₃(x = 0.65) is determined as the most efficient catalyst in the end. The Lewis acidity, Bronsted acidity and interaction of [Ps-MTH][CF₃SO₃] and FeCl₃ in [Ps-MTH][CF₃SO₃]-FeCl₃(x = 0.65) were characterized by FT-IR. And the catalytic mechanism of transesterification catalyzed by prepared IL was clarified. In order to maximize the biodiesel yield, optimization of process variables was conducted using Box-Behnken response surface methodol. The 97.04% of high biodiesel yield is obtained under the optimum conditions: reaction temperature was 127 °C, molar ratio (methanol to soapberry oil) was 27.96:1, catalyst amount was 3.06 mmol and reaction time was 8 h. Furthermore, [Ps-MTH][CF₃SO₃]-FeCl₃(x = 0.65) presents good catalytic activity in different transesterification for biodiesel production And its catalytic activity decreases from 97.04% to 93.59% after being used for 5 times, which reflects good reusability. The main properties of soapberry biodiesel were also measured and compared to the ASTM D6751 standard

Energy Conversion and Management published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, Related Products of pyrazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Hou, Zhong-Wei published the artcileElectrophotocatalytic C-H Azolation of Arenes, HPLC of Formula: 930-36-9, the publication is ChemElectroChem (2021), 8(9), 1571-1573, database is CAplus.

An electrophotocatalytic method was developed for the dehydrogenative cross coupling of arenes with azoles employing a bicatalytic system consisting of acridinium dye and (2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO). The reactions were conducted in a simple undivided cell with visible-light irradiation and requires no external chem. oxidant.

ChemElectroChem published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, HPLC of Formula: 930-36-9.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Abu Talip, Ruwaida Asyikin published the artcileUnderstanding the physicochemical and transport properties of pyrazolium based ionic liquids bearing iodide and triiodide anions, Category: pyrazoles-derivatives, the publication is Journal of Molecular Liquids (2022), 118270, database is CAplus.

Ionic liquids (ILs) particularly imidazolium-based ILs have been widely used in various industrial applications such as solvent or catalyst for synthesis, as electrolyte in energy devices, and as solvent for extraction and separation The extensive phys. and chem. properties data available on the imidazolium-based ILs have made them easier to be incorporated into variety of applications compared to other types of ionic liquids Ionic liquids composed of pyrazolium derivative as cation having the same heteroaromatic ring structure with imidazolium derivative except for the position of the nitrogen atoms, may result in unique phys. and chem. properties, yet have been minimally explored. The main objective of this study is to investigate the physicochem. and transport properties of pyrazolium-based ILs to fully comprehend their potential for further development for a specific task or application. In this study, three alkylpyrazolium iodides ILs as well as corresponding three alkylpyrazolium triiodides ILs were synthesized and characterized. The NMR anal. showed that the formation of alkylpyrazolium triiodides ILs from their resp. iodide precursors has resulted the resonance to be more deshielded due to lesser electron d. experienced by the acidic protons of pyrazolium cation due to the weakly localized charge in triiodide anion. The effect of different anions and the alkyl chain of the pyrazolium cation moiety has a pronounced effect on the phys. and transport properties of the synthesized ILs. It is found that the pyrazolium ionic liquids with triiodide anion demonstrated high thermal stability, low viscosity, and high ionic conductivity as compared to the iodide analogs.

Journal of Molecular Liquids published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, Category: pyrazoles-derivatives.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Almendros, Pedro published the artcileTransition metal-free controlled synthesis of bis[(trifluoromethyl)sulfonyl]ethyl-decorated heterocycles, Recommanded Product: 1-Methylpyrazole, the publication is Organic Chemistry Frontiers (2018), 5(21), 3163-3169, database is CAplus.

Several heterocycles reacted with shelf-stable 2-(2-fluoropyridinium-1-yl)-1,1-bis[(trifluoromethyl)sulfonyl]ethan-1-ide, a latent Tf₂C=CH₂ source, to give rise in a mild and controllable way to adducts via direct C-H bis[(trifluoromethyl)sulfonyl]ethylation reactions. This metal- and irradiation-free protocol is convenient. Besides, the volatile side-product 2-fluoropyridine can be smoothly eliminated under vacuum, which facilitates purification The substrate scope survey discloses that exquisite chemo- and regioselectivities are achieved in a variety of heterocyclic systems. Of particular interest are the late-stage structural modification of known pharmaceuticals, such as the marketed drugs phenazone (antipyrine) and edaravone, and the development of a water soluble fluorescent dye.

Organic Chemistry Frontiers published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, Recommanded Product: 1-Methylpyrazole.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Milner, Phillip J. published the artcileIn-Depth Assessment of the Palladium-Catalyzed Fluorination of Five-Membered Heteroaryl Bromides, Application of 1-Methylpyrazole, the publication is Organometallics (2015), 34(19), 4775-4780, database is CAplus and MEDLINE.

A thorough investigation of the challenging Pd-catalyzed fluorination of five-membered heteroaryl bromides is presented. Crystallog. studies and d. functional theory (DFT) calculations suggest that the challenging step of this transformation is C-F reductive elimination of five-membered heteroaryl fluorides from Pd(II) complexes. On the basis of these studies, we have found that various heteroaryl bromides bearing Ph groups in the ortho position can be effectively fluorinated under catalytic conditions. Highly activated 2-bromoazoles, such as 8-bromocaffeine, are also viable substrates for this reaction.

Organometallics published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, Application of 1-Methylpyrazole.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Kara, Belguzar Yasemin published the artcileA practical and highly efficient reductive dehalogenation of aryl halides using heterogeneous Pd/AlO(OH) nanoparticles and sodium borohydride, Application In Synthesis of 930-36-9, the publication is Tetrahedron (2016), 72(39), 5898-5902, database is CAplus.

The reductive dehalogenation of aryl halides was performed by using com. available aluminum oxy-hydroxide-supported palladium (Pd/AlO(OH)) nanoparticles of about 3 nm size (0.5 weight % Pd) with sodium borohydride. The dehalogenated products were obtained with absolute conversion in a mixture of H₂O/MeOH (volume/volume=1/1) under ultrasonic conditions at room temperature All aryl halides were successfully converted to halogen-free compounds within 1.5-4 h with yields of over 95%. The one-pot catalytic method is presented as a new process for the reductive dehalogenation of halogenated compounds This method is quite simple, highly efficient and eco-friendly, and has an exceptional recovery rate.

Tetrahedron published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C4H6N2, Application In Synthesis of 930-36-9.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics

Zhang, Shaoke published the artcileTowards a practical perfluoroalkylation of (hetero)arenes with perfluoroalkyl bromides using cobalt nanocatalysts, Computed Properties of 930-36-9, the publication is Catalysis Science & Technology (2020), 10(6), 1731-1738, database is CAplus.

A convenient methodol. for perfluoroalkylation including trifluoromethylation of (hetero)arenes with perfluoroalkyl bromides was developed. Key for the success is the use of a specific cobalt-based nanocatalyst, which can be recycled at least up to 4 times. The scope of this first cobalt-catalyzed perfluoroalkylation is presented.

Catalysis Science & Technology published new progress about 930-36-9. 930-36-9 belongs to pyrazoles-derivatives, auxiliary class Pyrazole, name is 1-Methylpyrazole, and the molecular formula is C14H26O2, Computed Properties of 930-36-9.

Referemce:
https://en.wikipedia.org/wiki/Pyrazole,
Pyrazoles – an overview | ScienceDirect Topics