Category: pyrazoles-derivatives

Product Details of 86-92-0. Recently I am researching about ENANTIOSELECTIVE ADDITION; TERTIARY ALCOHOLS; PYRAZOLONE DERIVATIVES; ORGANOZINC REAGENTS; ALKYLZINC REAGENTS; ALPHA-KETOESTERS; KETONES; DIETHYLZINC; HYDROXYLATION; DIMETHYLZINC, Saw an article supported by the Fundamental Research Funds for the Central UniversitiesFundamental Research Funds for the Central Universities [YJ201853, YJ201805]; National Natural Science FoundationNational Natural Science Foundation of China (NSFC) [21907072]. Published in WILEY-V C H VERLAG GMBH in WEINHEIM ,Authors: Wang, RH; Li, YL; He, HJ; Xiao, YC; Chen, FE. The CAS is 86-92-0. Through research, I have a further understanding and discovery of 3-Methyl-1-p-tolyl-5-pyrazolone

The catalytic enantioselective diorganozinc additions to cyclic diketones including pyrazolin-4,5-diones and isatins have been developed. In the presence of morpholine-containing chiral amino alcohol ligand, the corresponding chiral cyclic tertiary alcohols were produced in good to excellent yields (up to 97 %) and enantioselectivities (up to 95 % ee). The notable feature of this protocol includes its mild reaction conditions, Lewis acid additives free and broad functional group tolerance.

Product Details of 86-92-0. Welcome to talk about 86-92-0, If you have any questions, you can contact Wang, RH; Li, YL; He, HJ; Xiao, YC; Chen, FE or send Email.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

Novakova-Jiresova, A; Kopeckova, K; Boublikova, L; Chloupkov, R; Melichar, B; Petruzelka, L; Finek, J; Fiala, O; Grell, P; Batko, S; Linke, Z; Kiss, I; Prausov, J; Buchler, T in [Novakova-Jiresova, Alena; Boublikova, Ludmila; Buchler, Tomas] Charles Univ Prague, Fac Med 1, Dept Oncol, Videnska 800, Prague 14059, Czech Republic; [Novakova-Jiresova, Alena; Boublikova, Ludmila; Buchler, Tomas] Charles Univ Prague, Thomayer Hosp, Videnska 800, Prague 14059, Czech Republic; [Kopeckova, Katerina; Batko, Stanislav; Linke, Zdenek; Prausov, Jana] Charles Univ Prague, Univ Hosp Motol, Dept Oncol, Prague, Czech Republic; [Chloupkov, Renata] Masaryk Univ, Fac Med, Inst Biostat & Anal, Brno, Czech Republic; [Melichar, Bohuslav] Palacky Univ Med, Dept Oncol, Olomouc, Czech Republic; [Melichar, Bohuslav] Teaching Hosp, Olomouc, Czech Republic; [Petruzelka, Lubos] Charles Univ Prague, Gen Fac Hosp, Dept Oncol, Prague, Czech Republic; [Finek, Jindrich; Fiala, Ondrej] Charles Univ Prague, Med Sch, Dept Oncol & Radiotherapy, Plzen, Czech Republic; [Finek, Jindrich; Fiala, Ondrej] Charles Univ Prague, Univ Hosp Pilsen, Plzen, Czech Republic; [Fiala, Ondrej] Charles Univ Prague, Fac Med Pilsen, Biomed Ctr, Plzen, Czech Republic; [Grell, Peter; Kiss, Igor] Masaryk Mem Canc Inst, Dept Comprehens Canc Care, Brno, Czech Republic published Regorafenib for Metastatic Colorectal Cancer: An Analysis of a Registry-Based Cohort of 555 Patients in 2020, Cited 30. Recommanded Product: 83-10-3. The Name is 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid. Through research, I have a further understanding and discovery of 83-10-3.

Purpose: Regorafenib is an oral multikinase inhibitor approved for the therapy of previously treated metastatic colorectal carcinoma (mCRC). The aim of the present study was to analyze the outcomes of treatment with regorafenib in real-world clinical practice based on data from a national registry. Methods: The CORECT registry, the Czech non-interventional database of patients with mCRC treated with targeted agents, searched for patients with metastatic CRC treated with regorafenib. In total, 555 evaluable patients were identified. Results: The median age at diagnosis was 61.7 years. All patients had disease progression on or after previous systemic treatment. Most patients were treated with an initial dose of 160 mg daily (n = 463; 83.6%). The median duration of treatment was 2.7 months (range 0.023.4 months). By the data cut-off date, 472 patients (85%) had completed treatment with regorafenib and were evaluable for treatment response evaluation. Partial response was reported in 13 patients (2.8%) and disease stabilization in 130 patients (27.5%). Median progression-free survival (PFS) and overall survival (OS) were 3.5 months (95% confidence interval [CI] 3.2-3.7 months) and 9.3 months (95% CI 8.3-10.3 months), respectively. The 6-month OS rate was 67.7% (95% CI 63.4-72.1%). Multivariable analysis showed that female gender, longer interval from diagnosis of metastatic disease, MO stage at diagnosis, and Eastern Cooperative Oncology Group performance status (ECOG PS) 0 were associated with longer PFS, while higher body-mass index (BMI), longer interval from diagnosis of metastatic disease, and ECOG PS of 0 were associated with longer OS. Conclusion: OS of patients treated with regorafenib in the real-world clinical practice in this cohort exceeded that reported in randomized trials. Regorafenib is a safe and active treatment option for a subgroup of patients with mCRC who are progressing after other systemic therapies and maintain good performance status.

Recommanded Product: 83-10-3. Welcome to talk about 83-10-3, If you have any questions, you can contact Novakova-Jiresova, A; Kopeckova, K; Boublikova, L; Chloupkov, R; Melichar, B; Petruzelka, L; Finek, J; Fiala, O; Grell, P; Batko, S; Linke, Z; Kiss, I; Prausov, J; Buchler, T or send Email.

Reference:
Patent; Shanghai Pharmaceutical Industry Institute; China Pharmaceutical Industry Zongyuan; Li Jianqi; Huang Daowei; Wang Wenya; Zhang Zhiguo; Jiang Ling; (45 pag.)CN107286140; (2017); A;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

In 2020.0 J MOL LIQ published article about ENTHALPIES; VAPORIZATION in [Herrera-Castro, Filiberto; Alfonso Torres, Luis] Ctr Invest & Estudios Avanzados, Dept Quim, Av IPN 2508, Ciudad De Mexico 07360, Mexico in 2020.0, Cited 20.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. COA of Formula: C5H8N2

The study of the relationship between intermolecular interactions present in the solvation process and the magnitude of thermodynamic properties is extended from imidazole to pyrazole derivatives. The enthalpies of solution of pyrazole, 3,5-dimethylpyrazole and 3,4,5-trimethylpyrazole were calorimetrically determined in the solvents water, methanol and acetonitrile. The enthalpy of solution values for the three compounds in the three solvents are endothermic and spontaneous with an increase in entropy. As in the case with imidazole derivatives, the formation of a solution of pyrazole derivatives creates liquids that are more structured thermodynamically. The enthalpy of sublimation for 3,4,5-trimethylpyrazole, which is not available in the literature, was determined by the Knudsen effusion method. The combination of these thermodynamic properties has allowed the corresponding enthalpies of solvation to be obtained for the three pyrazole derivatives in the three selected solvents. With the use of the Pierotti equations and the enthalpies of solvation, the enthalpies of cavity formation were calculated along with the corresponding solute-solvent enthalpies of interaction. The infrared spectra and molecular volumes, as estimated through the electronic density, were used to obtain molecular insights into the solvation sensible sites within the studied solute molecules. The discussion of the solvation process and enthalpies of interaction of the pyrazole derivatives is based on the molecular structural features of solutes, specific intermolecular interactions and protic or aprotic nature of the solvents. The use of any empirical parameters in the discussion of the results was avoided. (C) 2020 Elsevier B.V. All rights reserved.

COA of Formula: C5H8N2. Welcome to talk about 67-51-6, If you have any questions, you can contact Herrera-Castro, F; Torres, LA or send Email.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

An article Association of Childhood Abuse with Incident Systemic Lupus Erythematosus in Adulthood in a Longitudinal Cohort of Women WOS:000522652200008 published article about POSTTRAUMATIC-STRESS-DISORDER; POPULATION-BASED SAMPLE; EMOTIONAL ABUSE; ELEVATED RISK; LIFE; ADVERSITY; HEALTH; MALTREATMENT; VICTIMIZATION; RECOLLECTIONS in [Feldman, Candace H.; Malspeis, Susan; Leatherwood, Cianna; Costenbader, Karen H.] Brigham & Womens Hosp, Dept Med, Div Rheumatol Immunol & Allergy, 75 Francis St, Boston, MA 02115 USA; [Feldman, Candace H.; Malspeis, Susan; Leatherwood, Cianna; Costenbader, Karen H.] Harvard Med Sch, Boston, MA 02115 USA; [Kubzansky, Laura; Roberts, Andrea L.] Harvard TH Chan Sch Publ Hlth, Boston, MA USA in 2019.0, Cited 49.0. SDS of cas: 67-51-6. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6

Objective. Exposure to severe stressors may alter immune function and augment inflammation and cytokine release, increasing risk of autoimmune disease. We examined whether childhood abuse was associated with a heightened risk of incident systemic lupus erythematosus (SLE). Methods. Data were drawn from the Nurses’ Health Study II, a cohort of US female nurses enrolled in 1989, followed with biennial questionnaires. We measured childhood physical and emotional abuse with the Physical and Emotional Abuse Subscale of the Childhood Trauma Questionnaire and sexual abuse with the Sexual Maltreatment Scale of the Parent-Child Conflict Tactics Scale, both administered in 2001. We identified incident SLE (>= 4 American College of Rheumatology 1997 classification criteria) through 2015. We used multivariable Cox regression models to evaluate the association between childhood abuse and SLE, accounting for potential confounders (e.g., parental education, occupation, home ownership) and mediators [e.g., depression, posttraumatic stress disorder (PTSD)]. Results. Among 67,516 women, there were 94 cases of incident SLE. In adjusted models, exposure to the highest versus lowest physical and emotional abuse was associated with 2.57 times greater risk of SLE (95% CI 1.30-5.12). We found that 17% (p < 0.0001) of SLE risk associated with abuse could be explained by depression and 23% (p < 0.0001) by PTSD. We did not observe a statistically significant association with sexual abuse (HR 0.84, 95% CI 0.40-1.77, highest vs lowest exposure). Conclusion. We observed significantly increased risk of SLE among women who had experienced childhood physical and emotional abuse compared with women who had not. Exposure to childhood adversity may contribute to development of SLE. SDS of cas: 67-51-6. Welcome to talk about 67-51-6, If you have any questions, you can contact Feldman, CH; Malspeis, S; Leatherwood, C; Kubzansky, L; Costenbader, KH; Roberts, AL or send Email.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Authors Milne, IA; Graham, JMR in CAMBRIDGE UNIV PRESS published article about in [Milne, I. A.] Univ Western Australia, Oceans Grad Sch, Crawley 6009, Australia; [Graham, J. M. R.] Imperial Coll London, Dept Aeronaut, London SW7 2AZ, England in 2019, Cited 13. Computed Properties of C12H12N2O3. The Name is 1,5-Dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxylic acid. Through research, I have a further understanding and discovery of 83-10-3

The changes in spectra and intensities of the streamwise component of turbulent velocity are calculated in the inflow of a turbine rotor. The flow is initially calculated in the limit when the turbulence is of small scale compared with the rotor diameter. Rapid distortion theory (RDT), Batchelor & Proudman (Q. J. Mech. Appl. Maths, vol. 7 (1), 1954, pp. 83-103) (BP), for small-scale turbulence is combined with the effect of the fluctuating potential flow field on the turbulence caused by the direct interaction of the incident turbulence with the rotor as a sheet of resistance. A second computation is then carried out for turbulence of larger length scale. The results of the calculations are compared with velocity measurements in the inflow of both a commercial wind turbine and a tidal turbine rotor.

Computed Properties of C12H12N2O3. Welcome to talk about 83-10-3, If you have any questions, you can contact Milne, IA; Graham, JMR or send Email.

Reference:
Patent; Shanghai Pharmaceutical Industry Institute; China Pharmaceutical Industry Zongyuan; Li Jianqi; Huang Daowei; Wang Wenya; Zhang Zhiguo; Jiang Ling; (45 pag.)CN107286140; (2017); A;,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

An article Synthesis and photophysical properties of butterfly-shaped dinuclear Pt(II) complex having NHC-based chelate ligands WOS:000471754200006 published article about PHOSPHORESCENT MOLECULAR BUTTERFLIES; AGGREGATION-INDUCED EMISSION; WHITE-LIGHT EMISSION; PLATINUM(II) COMPLEXES; HETEROPOLYNUCLEAR COMPLEXES; QUANTUM YIELDS; EFFICIENT; LUMINESCENCE; HYDROGEN; AG in [Moon, Sangjoon; Horiuchi, Shinnosuke; Sakuda, Eri; Arikawa, Yasuhiro; Umakoshi, Keisuke] Nagasaki Univ, Grad Sch Engn, Div Chem & Mat Sci, Bunkyo Machi, Nagasaki 8528521, Japan; [Ito, Akitaka] Kochi Univ Technol, Grad Sch Engn, 185 Miyanokuchi, Kochi 7821502, Japan in 2019.0, Cited 48.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. Quality Control of 3,5-Dimethyl-1H-pyrazole

A butterfly-shaped dinuclear Pt(II) complex having pyridyl-NHC chelate ligands and bridging Me(2)pz ligands was synthesized. The crystal structure of the Pt-2 complex showed short intramolecular Pt center dot center dot center dot Pt distance (3.129 angstrom) and unique packing structure containing one-dimensional infinite pore that was filled with solvent molecules. The absorbance was proportional to the concentration of Pt-2 complex and no significant bands appeared even in high concentration (up to 100 mu M). The Pt-2 complex showed bluish-green emission (lambda(max) = 459 nm) in the solid state at 298 K (lambda(ex) = 330 nm). TD-DFT calculation revealed that the lowest-energy absorption bands are mainly assigned to the combination of metal-to-ligand charge transfer (MLCT) and ligand-to-ligand charge transfer (LLCT) transitions.

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Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Recommanded Product: 3-Methyl-1-p-tolyl-5-pyrazolone. In 2019 ORG LETT published article about ALLYLIC DEAROMATIZATION REACTION; STEREOCONTROLLED CONSTRUCTION; MICHAEL ADDITION; ALKYLATION; ACID; PYRAZOLIN-5-ONES; PYRAZOL-5-ONES; ALCOHOLS; BEARING in [Wu, Gengxin; Xu, Haohan; Liu, Ziran; Liu, Yonghong; Yang, Xiang; Huang, Yan] Xinjiang Univ, Coll Chem & Chem Engn, Key Lab Oil & Gas Fine Chem, Minist Educ & Xinjiang Uyghur Autonomous Reg, Urumqi 830000, Xinjiang, Peoples R China; [Zhang, Xulong] Xinjiang Uygur Autonomous Reg Prod Qual Supervis, Urumqi 830000, Xinjiang, Peoples R China in 2019, Cited 46. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0.

In this letter, an efficient one-pot asymmetric sequential reaction is achieved by organo/transition metal relay catalysis in constructing two consecutive C-C bonds, which involves enantioselective amino squaramide catalytic Mannich-type addition of pyrazolones to isatin-derived ketimines and a subsequent palladium catalyzed diastereoselective allylic alkylation of pyrazolones with allylic acetates. An array of novel pyrazolone-aminooxindole-propylene structural motifs are obtained in a high level of yield and with excellent enantio- and diastereoselectivity (up to 95% yield, >20:1 dr, >99% ee). This methodology features the formation of vicinal quarternary carbon-stereocenters, and the second all-carbon tetrasubstituted stereogenic center is induced by joint action of the achiral palladium catalysis and the chiral environment generated from the Mannich step. Moreover, the usefulness of this methodology is highlighted by converting the allylic product into the carbonyl compound.

Recommanded Product: 3-Methyl-1-p-tolyl-5-pyrazolone. Bye, fridends, I hope you can learn more about C11H12N2O, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

In 2020.0 APPL ORGANOMET CHEM published article about CRYSTAL-STRUCTURES; COPPER(II)-ASSISTED HYDROLYSIS; CARBONYL-COMPLEXES; RHODIUM COMPLEXES; 2,4,6-TRIS(2-PYRIDYL)-1,3,5-TRIAZINE; COPPER; 2,4,6-TRIS(2-PYRIMIDYL)-1,3,5-TRIAZINES; RUTHENIUM(II); FUNCTIONALS; MONONUCLEAR in [Soliman, Saied M.; El-Faham, Ayman] Alexandria Univ, Fac Sci, Dept Chem, POB 426, Alexandria 21321, Egypt; [El-Faham, Ayman] King Saud Univ, Coll Sci, Dept Chem, POB 2455, Riyadh 11451, Saudi Arabia; [El Silk, Sobhy E.] Tanta Univ, Fac Sci, Bot Dept, Bacteriol Unit, Tanta 31527, Egypt in 2020.0, Cited 70.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. Application In Synthesis of 3,5-Dimethyl-1H-pyrazole

Two unexpected one-dimensional coordination polymers, [Cu(PT)(H2O)Cl](n) 1 and [Cu-2(BPT)(ClO4)(3)(H2O)(4)](n)center dot 2nH(2)O 2, of symmetrical triazine-based ligands were synthesized by Cu(II)-mediated hydrolysis of the 2,4-bis(3,5-dimethyl-1H-pyrazol-1-yl)-6-methoxy-1,3,5-triazine (MBPT) pincer ligand. The reaction of Cu(ClO4)(2)center dot 6H(2)O with MBPT proceeded via hydrolysis of the methoxy group to produce the dicompartmental 4,6-bis(3,5-dimethyl-1H-pyrazol-1-yl)-1,3,5-triazin-2(1H)-one ligand (HBPT) that then undergoes in situ complexation with Cu(II) to afford 2. In case of CuCl2, the reaction proceeds further with C-N cleavage of one pyrazolyl unit leading to the formation of 6-(3,5-dimethyl-1H-pyrazol-1-yl)-1,3,5-triazine-2,4(1H,3H)-dione ligand (HPT) that also undergoes in situ complexation with Cu(II) affording 1. The role of Cu(II) is to increase the Lewis acid reactivity of the water molecule where similar hydrolytic reactions for MBPT were observed in acidic medium in presence of an aqueous HCl (1:1 v/v) solution. The molecular and supramolecular structures of complexes 1 and 2 were investigated using X-ray diffraction of single crystal, Hirshfeld analysis, and density functional theory calculations. The Cl center dot center dot center dot H (11.7%) and O center dot center dot center dot H (24.7%) contacts are the most important in 1, whereas the molecular packing of 2 is controlled mainly by the O center dot center dot center dot H (58.7%) hydrogen bonds. Complex 2 showed better activity against Escherichia coli, Bacillus subtilis, and Candida albicans compared with the standard antibiotics amoxicillin, tetracycline, and ampicillin. In general, complexes 1 and 2 showed good antimicrobial activity than these antibiotics and have the advantage to be used as both antibacterial and antifungal agents.

Application In Synthesis of 3,5-Dimethyl-1H-pyrazole. About 3,5-Dimethyl-1H-pyrazole, If you have any questions, you can contact Soliman, SM; El-Faham, A; El Silk, SE or concate me.

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics

Shaikh, I; Jadeja, RN; Patel, R in [Shaikh, Irfan; Jadeja, R. N.] Maharaja Sayajirao Univ Baroda, Fac Sci, Dept Chem, Vadodara 390002, India; [Patel, Rajesh] Veer Narmad South Gujarat Univ, Dept Biosci, Surat 395007, India published Three mixed ligand mononuclear Zn(II) complexes of 4-acyl pyrazolones: Synthesis, characterization, crystal study and anti-malarial activity in 2020, Cited 33. Application In Synthesis of 3-Methyl-1-p-tolyl-5-pyrazolone. The Name is 3-Methyl-1-p-tolyl-5-pyrazolone. Through research, I have a further understanding and discovery of 86-92-0.

Three novel mixed ligand Zn(II) complexes {complex 1 = [Zn(L1)(2)(bpy)], complex 2 = [Zn(L2)(2)(bPY)], complex 3 = [Zn(L2)(2)(phen)], where bpy = 2,2′-bipyridine and phen = 1,10-phenanthroline} of 4-(4-chlorobenzoyl)-2-(3-chlorophenyl)-5-methyl-2,4-dihydro-3H-pyrazol-3-one (HL1) and 4-(4-chlorobenzoyl)-5-methyl-2-(p-tolyl)-2,4-dihydro-3H-pyrazol-3-one (HL2) were synthesized and characterized by H-1 and C-13 NMR, FTIR, TG-DTA, UV-Vis, elemental analysis, molar conductance and single crystal X-ray structure determination. Based on analytical and spectroscopic techniques, all the three Zn(II) complexes were found to have a distorted octahedral geometry. The ligands and the complexes were screened for antimalarial activity against plasmodium falciparum. The zinc(II) complexes showed greater antimalarial activity than their parent ligands. (C) 2020 Elsevier Ltd. All rights reserved.

Application In Synthesis of 3-Methyl-1-p-tolyl-5-pyrazolone. Bye, fridends, I hope you can learn more about C11H12N2O, If you have any questions, you can browse other blog as well. See you lster.

Reference:
Article; Zhang, Yong; Nie, Long-Jun; Luo, Liang; Mao, Jia-Xin; Liu, Jin-Xiang; Xu, Guo-Hai; Chen, Deliang; Luo, Hai-Qing; Tetrahedron; vol. 76; 7; (2020);,
Pyrazole – Wikipedia,
Pyrazoles – an overview | ScienceDirect Topics

An article Synthesis and photoinitiating ability of substituted 4,5-di-tert-alkyl-o-benzoquinones in radical polymerization WOS:000647018700020 published article about TRANSITION-METAL-COMPLEXES; O-QUINONE; ELECTROCHEMICAL TRANSFORMATIONS; CATECHOL; 1,2-BENZOQUINONES; METHACRYLATE; DERIVATIVES; TRIPTYCENE; REDUCTION in [Zherebtsov, M. A.; Zhiganshina, E. R.; Lenshina, N. A.; Kovylin, R. S.; Baranov, E., V; Shushunova, N. Yu; Shurygina, M. P.; Arsenyev, M., V; Chesnokov, S. A.; Cherkasov, V. K.] Russian Acad Sci, GA Razuvaev Inst Organometall Chem, 49 Ul Tropinina, Nizhnii Novgorod 603600, Russia; [Zherebtsov, M. A.; Arsenyev, M., V; Cherkasov, V. K.] NI Lobachevsky Nizhny Novgorod State Univ, 23 Prosp Gagarina, Nizhnii Novgorod 603950, Russia in 2021.0, Cited 60.0. The Name is 3,5-Dimethyl-1H-pyrazole. Through research, I have a further understanding and discovery of 67-51-6. Application In Synthesis of 3,5-Dimethyl-1H-pyrazole

New tri- and tetraalkyl-substituted o-benzoquinones were synthesized based on 5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2,3-diol derivatives. The new compounds were characterized by spectroscopic and electrochemical methods. The reactivity of o-benzoquinones was evaluated in the photoreduction and initiation of photopolymerization of oligocarbonate dimethacrylate (OCM-2) in the presence of N,N-dimethylcyclohexylamine and in the inhibition of MMA polymerization. The introduction of the methyl substituent into the benzene ring has a weak effect on the inhibitory activity of o-benzoquinone, whereas the (3,5-dimethylpyrazol-1-yl)methyl substituent enhances the inhibitory effect of 4,5-di-tert-alkyl-substituted o-benzoquinone.

Welcome to talk about 67-51-6, If you have any questions, you can contact Zherebtsov, MA; Zhiganshina, ER; Lenshina, NA; Kovylin, RS; Baranov, EV; Shushunova, NY; Shurygina, MP; Arsenyev, MV; Chesnokov, SA; Cherkasov, VK or send Email.. Application In Synthesis of 3,5-Dimethyl-1H-pyrazole

Reference:
Pyrazole – Wikipedia,
,Pyrazoles – an overview | ScienceDirect Topics